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The map label for this gene is lspA [H]

Identifier: 154246149

GI number: 154246149

Start: 2466313

End: 2466846

Strand: Reverse

Name: lspA [H]

Synonym: Xaut_2206

Alternate gene names: 154246149

Gene position: 2466846-2466313 (Counterclockwise)

Preceding gene: 154246150

Following gene: 154246148

Centisome position: 46.47

GC content: 66.1

Gene sequence:

>534_bases
ATGGGCCGACGCCACATCCTCTTCGGCCTTCTCGTCGCGGTCCTCGTCCTGGTGGTGGACCAGGCGACCAAGAGCCTCGT
CCTCGCCTGGTCGCGCCAGTGGGTGGATCCGCTCCACACGGTGGCGCCGGGGCTGGATTTCGTGGCGCTGTGGAACAGCG
GCATCAGCTACGGCCTGTTCCCGCAGGGCGAGACCGGGCGCTGGGTGCTGGTGGCCATCAAGGTGGCCGCCGCCCTGCTC
TTCACCGTCTGGCTGACGCGATCGCGGGGGCGGCTGGAAGCCTTCTCCCTCGGCCTTCTCATCGGCGGCGCCATCGGCAA
TGCGGTGGACCGGGTGGTCTATGGCGCGGTGTTCGACTTCGTCTCGCTCCACGCCATGGGCTACCGCTGGTACGTATTCA
ACGTGGCCGATGTGGCCGTGGTTGTAGGGGTGGGGCTGCTTCTTTATGATGCGTTTTTAGGTCGCGCCTCAAAATTGCCG
CCCTCGGTCCCGCCAATGGCGGCGAAATCCGAAGCTGAGCGTGAGCGAAGCTGA

Upstream 100 bases:

>100_bases
GAGGTGGGCACCGATCCGCAGTTCCCGGACGTGACCCCGCGCGACGCGGACGCCTTGCGGGAATTTTTCGCCGCCCAGAC
GGCGGCGCAGTGAGGTGACG

Downstream 100 bases:

>100_bases
GCGCGAGCTCTGAAGGGCTGCCCAAAGGCCTCAGGGAAACCAGACGTCGGGGAAACAGGAACCATGCGCGTGAGCTCGAA
TTTTTCACGCGGCGTCGCCG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MGRRHILFGLLVAVLVLVVDQATKSLVLAWSRQWVDPLHTVAPGLDFVALWNSGISYGLFPQGETGRWVLVAIKVAAALL
FTVWLTRSRGRLEAFSLGLLIGGAIGNAVDRVVYGAVFDFVSLHAMGYRWYVFNVADVAVVVGVGLLLYDAFLGRASKLP
PSVPPMAAKSEAERERS

Sequences:

>Translated_177_residues
MGRRHILFGLLVAVLVLVVDQATKSLVLAWSRQWVDPLHTVAPGLDFVALWNSGISYGLFPQGETGRWVLVAIKVAAALL
FTVWLTRSRGRLEAFSLGLLIGGAIGNAVDRVVYGAVFDFVSLHAMGYRWYVFNVADVAVVVGVGLLLYDAFLGRASKLP
PSVPPMAAKSEAERERS
>Mature_176_residues
GRRHILFGLLVAVLVLVVDQATKSLVLAWSRQWVDPLHTVAPGLDFVALWNSGISYGLFPQGETGRWVLVAIKVAAALLF
TVWLTRSRGRLEAFSLGLLIGGAIGNAVDRVVYGAVFDFVSLHAMGYRWYVFNVADVAVVVGVGLLLYDAFLGRASKLPP
SVPPMAAKSEAERERS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=154, Percent_Identity=31.1688311688312, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19224; Mature: 19093

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRHILFGLLVAVLVLVVDQATKSLVLAWSRQWVDPLHTVAPGLDFVALWNSGISYGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
PQGETGRWVLVAIKVAAALLFTVWLTRSRGRLEAFSLGLLIGGAIGNAVDRVVYGAVFDF
CCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLHAMGYRWYVFNVADVAVVVGVGLLLYDAFLGRASKLPPSVPPMAAKSEAERERS
HHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
GRRHILFGLLVAVLVLVVDQATKSLVLAWSRQWVDPLHTVAPGLDFVALWNSGISYGLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
PQGETGRWVLVAIKVAAALLFTVWLTRSRGRLEAFSLGLLIGGAIGNAVDRVVYGAVFDF
CCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLHAMGYRWYVFNVADVAVVVGVGLLLYDAFLGRASKLPPSVPPMAAKSEAERERS
HHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA