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The map label for this gene is 154246104

Identifier: 154246104

GI number: 154246104

Start: 2422470

End: 2423051

Strand: Reverse

Name: 154246104

Synonym: Xaut_2161

Alternate gene names: NA

Gene position: 2423051-2422470 (Counterclockwise)

Preceding gene: 154246105

Following gene: 154246103

Centisome position: 45.64

GC content: 68.73

Gene sequence:

>582_bases
ATGGTGAAGCTGAACAAGATCTACACGCGCACCGGCGACGACGGCACAACTGGCCTTGGCACCGGCGCGCGGGTACCCAA
ATACGACCTGCGCGTAGACGCCTACGGCGCGGTGGACGAGACCAACGCCGCCATCGGCCTCGCCCGCCTGCATCTTTCGG
GCGAAGTGGTGCTCGATGCCATGCTCATGCGTGTGCAGAATGATCTGTTCGATCTCGGCGCCGACCTGTGCGTGCCCCCC
AAGGCGGACGAGGCGGCGGGCGCGGCGCTGCGTGTCATTCCAGCGCAGGTGAGCCGGCTGGAAAGCGACATCGACCTGCT
GAATGCCGAGCTGTCGCCCCTCACCTCCTTCATCCTGCCGGCGGGATCGCCGGCATCCGCCCACCTGCATTTCGCCCGCA
CCGTCTGCCGGCGCGCCGAGCGCATCATGGTGGAGTTGTCGCACCAGCCGGACGAGAGCGTGGGCGGGCCGGCCATCCAC
TATGTGAACCGCCTGTCGGACCTGCTGTTCGTGGCCGGCCGCTACGCCAACGCCCGCGGCGCCGCCGACGTGCTCTGGGT
GCCGGGAGCCAGCCGCACCTGA

Upstream 100 bases:

>100_bases
GTTCCAGTTCGGCGCCATCATCCTGGTGATGATCACCATCTTCGCCATGGGGCGGTGAGCTGGGTCGGCACGCTCGGACG
CTGAGAGGAACTGCAGCCAG

Downstream 100 bases:

>100_bases
CGCCGAGCCGGACCCACGAGACGGCCTCCAAGCAAGTGATGAGAGCGCACCCTCCGCCCACCGGCGGGGTGGCGCGTCCC
GGATCGTCACTCCGGCGCAT

Product: ATP--cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MVKLNKIYTRTGDDGTTGLGTGARVPKYDLRVDAYGAVDETNAAIGLARLHLSGEVVLDAMLMRVQNDLFDLGADLCVPP
KADEAAGAALRVIPAQVSRLESDIDLLNAELSPLTSFILPAGSPASAHLHFARTVCRRAERIMVELSHQPDESVGGPAIH
YVNRLSDLLFVAGRYANARGAADVLWVPGASRT

Sequences:

>Translated_193_residues
MVKLNKIYTRTGDDGTTGLGTGARVPKYDLRVDAYGAVDETNAAIGLARLHLSGEVVLDAMLMRVQNDLFDLGADLCVPP
KADEAAGAALRVIPAQVSRLESDIDLLNAELSPLTSFILPAGSPASAHLHFARTVCRRAERIMVELSHQPDESVGGPAIH
YVNRLSDLLFVAGRYANARGAADVLWVPGASRT
>Mature_193_residues
MVKLNKIYTRTGDDGTTGLGTGARVPKYDLRVDAYGAVDETNAAIGLARLHLSGEVVLDAMLMRVQNDLFDLGADLCVPP
KADEAAGAALRVIPAQVSRLESDIDLLNAELSPLTSFILPAGSPASAHLHFARTVCRRAERIMVELSHQPDESVGGPAIH
YVNRLSDLLFVAGRYANARGAADVLWVPGASRT

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=179, Percent_Identity=40.7821229050279, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI115534154, Length=179, Percent_Identity=35.7541899441341, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20574; Mature: 20574

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLNKIYTRTGDDGTTGLGTGARVPKYDLRVDAYGAVDETNAAIGLARLHLSGEVVLDA
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHEEEEEEECCHHHHHHH
MLMRVQNDLFDLGADLCVPPKADEAAGAALRVIPAQVSRLESDIDLLNAELSPLTSFILP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
AGSPASAHLHFARTVCRRAERIMVELSHQPDESVGGPAIHYVNRLSDLLFVAGRYANARG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
AADVLWVPGASRT
CCEEEECCCCCCC
>Mature Secondary Structure
MVKLNKIYTRTGDDGTTGLGTGARVPKYDLRVDAYGAVDETNAAIGLARLHLSGEVVLDA
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHEEEEEEECCHHHHHHH
MLMRVQNDLFDLGADLCVPPKADEAAGAALRVIPAQVSRLESDIDLLNAELSPLTSFILP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
AGSPASAHLHFARTVCRRAERIMVELSHQPDESVGGPAIHYVNRLSDLLFVAGRYANARG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
AADVLWVPGASRT
CCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]