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The map label for this gene is dapE [H]

Identifier: 154246036

GI number: 154246036

Start: 2353572

End: 2354663

Strand: Reverse

Name: dapE [H]

Synonym: Xaut_2093

Alternate gene names: 154246036

Gene position: 2354663-2353572 (Counterclockwise)

Preceding gene: 154246042

Following gene: 154246035

Centisome position: 44.35

GC content: 69.05

Gene sequence:

>1092_bases
GTGACGCCGCACGCGGACGATGCGCTGGAGCTGGTGGCGAAAAGGCTGGAGGCCGCTGGGTACCGCGTGGAGCGCCTGAC
CTTCGAGACCGGCGGCGTGCCCATCCCCAATCTCTACGCCCGTATCGGCACCGACGGCCCGAACCTGTGCTTCGCCGGGC
ATGTGGACGTGGTACCCGAGGGAGATGCCACCCAATGGCACCACGCCCCCTTCGCCGGCACGGTTGAGGACGGCGTGCTC
CATGGGCGTGGGGCGGTGGACATGAAGGGGGCGGTGGCCGCCTTCCTCGCCGCCGCGCTCGCCTTCGGCCGGCCGCAGCG
CGGCAGCCTCTCCTTCCTCATCACCGGCGACGAGGAAGGCCCGGCGCTGGACGGCACCGTGAAGGTGGTGGAGTGGCTGA
AGGCCAGGGGCGAGACCATCGACCATTGCGTGCTGGGCGAGCCCACCAACCCCGATGCCCTGGGCGATGCCTTCAAGGTC
GGCCGGCGCGGCAGCCTCTCCGGCATCCTCACCGTGAAGGGCGTGCAGGGGCACGTGGCCTATCCGCACCTTGCCGACAA
TCCCATTCCGCGCCTCCTGAAGCTCATCGGCGACCTGACCGCCGCCCCCCTCGACCACGGCTCGGATTTCTTCCCGCCCT
CCAACCTGGAGGTGGTCTCGGTGGACGTGGGCAATCCGGTATTCAACCTGATCCCCGCGCAGGCCACCGCCCGCTTCAAC
GTGCGCTTCAACGACCTGTTCTCGCTGGAGAGCCTGAAGTCCGAGATCATCCGCCGCCTCGACGGCGCCGGCCTCACCTA
CGACCTCGCATTCCAGACCGGGGCGAGCCAGAGCTTCCTCACCGCCCCCGGCCCGTTCACGGACCTCGTCGCCAGCGCGG
TGGAAGAGGTGACCGGGCGCCGGCCCGAGCCCTCCACCTCGGGCGGCACCTCGGATGCGCGCTTCATCAAGGACATCTGC
CCGGTGGTGGAATTCGGCCTCGTGGGCCGCACCATGCACAAGGTGGACGAGGCGACGCCGGTCAAGGACATCGAGGCTCT
CACCGCCATCTACGGCCGCATCATCGCCCGCTATTTCTCAACCTTCGCGTGA

Upstream 100 bases:

>100_bases
CCAGGCTGCACCTTCCGACCCCATTGCCGCCCCGATTGCCGCCTCCCCGGCCACCCCCGATCCGGTGGCGCTGGCCGCCG
AGCTGATCCGCGCGCCTTCG

Downstream 100 bases:

>100_bases
GTTCGCATGATGCCCGGTGAAACGACACTCGACGAAGACTTCTCCCGCCTCGACGTGGACGGCCGCGACATTGCCGTGCG
CAGCGTGGCCGGCGCGACGC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTPHADDALELVAKRLEAAGYRVERLTFETGGVPIPNLYARIGTDGPNLCFAGHVDVVPEGDATQWHHAPFAGTVEDGVL
HGRGAVDMKGAVAAFLAAALAFGRPQRGSLSFLITGDEEGPALDGTVKVVEWLKARGETIDHCVLGEPTNPDALGDAFKV
GRRGSLSGILTVKGVQGHVAYPHLADNPIPRLLKLIGDLTAAPLDHGSDFFPPSNLEVVSVDVGNPVFNLIPAQATARFN
VRFNDLFSLESLKSEIIRRLDGAGLTYDLAFQTGASQSFLTAPGPFTDLVASAVEEVTGRRPEPSTSGGTSDARFIKDIC
PVVEFGLVGRTMHKVDEATPVKDIEALTAIYGRIIARYFSTFA

Sequences:

>Translated_363_residues
MTPHADDALELVAKRLEAAGYRVERLTFETGGVPIPNLYARIGTDGPNLCFAGHVDVVPEGDATQWHHAPFAGTVEDGVL
HGRGAVDMKGAVAAFLAAALAFGRPQRGSLSFLITGDEEGPALDGTVKVVEWLKARGETIDHCVLGEPTNPDALGDAFKV
GRRGSLSGILTVKGVQGHVAYPHLADNPIPRLLKLIGDLTAAPLDHGSDFFPPSNLEVVSVDVGNPVFNLIPAQATARFN
VRFNDLFSLESLKSEIIRRLDGAGLTYDLAFQTGASQSFLTAPGPFTDLVASAVEEVTGRRPEPSTSGGTSDARFIKDIC
PVVEFGLVGRTMHKVDEATPVKDIEALTAIYGRIIARYFSTFA
>Mature_362_residues
TPHADDALELVAKRLEAAGYRVERLTFETGGVPIPNLYARIGTDGPNLCFAGHVDVVPEGDATQWHHAPFAGTVEDGVLH
GRGAVDMKGAVAAFLAAALAFGRPQRGSLSFLITGDEEGPALDGTVKVVEWLKARGETIDHCVLGEPTNPDALGDAFKVG
RRGSLSGILTVKGVQGHVAYPHLADNPIPRLLKLIGDLTAAPLDHGSDFFPPSNLEVVSVDVGNPVFNLIPAQATARFNV
RFNDLFSLESLKSEIIRRLDGAGLTYDLAFQTGASQSFLTAPGPFTDLVASAVEEVTGRRPEPSTSGGTSDARFIKDICP
VVEFGLVGRTMHKVDEATPVKDIEALTAIYGRIIARYFSTFA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=361, Percent_Identity=42.9362880886427, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1790395, Length=200, Percent_Identity=30, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 38596; Mature: 38465

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHADDALELVAKRLEAAGYRVERLTFETGGVPIPNLYARIGTDGPNLCFAGHVDVVPE
CCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHEECCCCCCEEEECCEEECCC
GDATQWHHAPFAGTVEDGVLHGRGAVDMKGAVAAFLAAALAFGRPQRGSLSFLITGDEEG
CCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
PALDGTVKVVEWLKARGETIDHCVLGEPTNPDALGDAFKVGRRGSLSGILTVKGVQGHVA
CCCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEE
YPHLADNPIPRLLKLIGDLTAAPLDHGSDFFPPSNLEVVSVDVGNPVFNLIPAQATARFN
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHEEECCCCEEEEE
VRFNDLFSLESLKSEIIRRLDGAGLTYDLAFQTGASQSFLTAPGPFTDLVASAVEEVTGR
EEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCC
RPEPSTSGGTSDARFIKDICPVVEFGLVGRTMHKVDEATPVKDIEALTAIYGRIIARYFS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TFA
HCC
>Mature Secondary Structure 
TPHADDALELVAKRLEAAGYRVERLTFETGGVPIPNLYARIGTDGPNLCFAGHVDVVPE
CCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHEECCCCCCEEEECCEEECCC
GDATQWHHAPFAGTVEDGVLHGRGAVDMKGAVAAFLAAALAFGRPQRGSLSFLITGDEEG
CCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
PALDGTVKVVEWLKARGETIDHCVLGEPTNPDALGDAFKVGRRGSLSGILTVKGVQGHVA
CCCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEE
YPHLADNPIPRLLKLIGDLTAAPLDHGSDFFPPSNLEVVSVDVGNPVFNLIPAQATARFN
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHEEECCCCEEEEE
VRFNDLFSLESLKSEIIRRLDGAGLTYDLAFQTGASQSFLTAPGPFTDLVASAVEEVTGR
EEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCC
RPEPSTSGGTSDARFIKDICPVVEFGLVGRTMHKVDEATPVKDIEALTAIYGRIIARYFS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TFA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA