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The map label for this gene is zraR [H]

Identifier: 154246012

GI number: 154246012

Start: 2327927

End: 2328691

Strand: Reverse

Name: zraR [H]

Synonym: Xaut_2069

Alternate gene names: 154246012

Gene position: 2328691-2327927 (Counterclockwise)

Preceding gene: 154246024

Following gene: 154246011

Centisome position: 43.86

GC content: 72.55

Gene sequence:

>765_bases
ATGACCCTGCCCCTGCTTCTGGTCGAAGATGACCCTGTCGAGGCGCGCCGCCTCTCGTCGGCCCTCGCCGGCCTTGGCTA
CGAGGTGACGCTGGCCGAGGATGGCGACGCGGCGCTGGACCAGCTGGCCGCCGGCACCTTCGACGTGGTGCTGTTGGATC
TGGTGGTGCCGGGCCTCGACGGCATGGGCGTGCTCGACGCCATGGCGGCGCGCGGACTTGCGGTTCCGGTGGTGGTGCAG
GTGACGGCGGCCGGGCTCGATGCCGCCTCGGGCGCCATTCGCGCCGGCGCGCGGGATTTCGTGGTGAAGCCGGCCGGGGC
GCTGCGCCTGCAGGTGGCCCTTGCCAATGCGGTGGCCCTCGGCCGCGCCGCCCCGCCGACGACCCGGCCCGCGCGGACCC
AGCCAGACAACGCACAGCCGGACAATGTGGTGGCCTTCACCCCCGCGTCCGGCCCATTCGTCGTTGCGCCGCCCCCGCTC
CGCGACAGCGGGACGGAATCCCCCCTGCCCCCGCTTCTGCGGACCGAAAGCCTGGCTTACGCCCGCCTCGACGCTGCCGG
CCATGCCCGCCGGCTGGAGCAGATCGAGGCCGAGGCCATCCGCTTTGCCTGCCACCTCTATGGCGGGCGCATGGCGGAGG
TGGCCCGCCGCCTCGGCATCGGCCGCTCCACCCTCTACCGCAAGCTCGCTGAACTGGATGCCGATACGGTAGGCGGCAAC
CGCGATGTGGAACCAGATGCCGCGCGGTTTGTTGCCGCTGAGTGA

Upstream 100 bases:

>100_bases
GGGCCGGGGCGGCCAGGGCGGAGGTGCTCAGGGGTTCTTAACCATCGCCCGCCAAGCTCCCGGTGATTCTCTCTTCCGTC
CTGCCGCAAGCGATTCCTGA

Downstream 100 bases:

>100_bases
CAAGGCAGTGAAAACCTTGGCCCGCTCAAGCTTGTGAGTTGATCGGAACGCCGGAGCACGGCACCAACGGGCGGGGCTGT
GGCGAGGAGAAGGCCATGTT

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTLPLLLVEDDPVEARRLSSALAGLGYEVTLAEDGDAALDQLAAGTFDVVLLDLVVPGLDGMGVLDAMAARGLAVPVVVQ
VTAAGLDAASGAIRAGARDFVVKPAGALRLQVALANAVALGRAAPPTTRPARTQPDNAQPDNVVAFTPASGPFVVAPPPL
RDSGTESPLPPLLRTESLAYARLDAAGHARRLEQIEAEAIRFACHLYGGRMAEVARRLGIGRSTLYRKLAELDADTVGGN
RDVEPDAARFVAAE

Sequences:

>Translated_254_residues
MTLPLLLVEDDPVEARRLSSALAGLGYEVTLAEDGDAALDQLAAGTFDVVLLDLVVPGLDGMGVLDAMAARGLAVPVVVQ
VTAAGLDAASGAIRAGARDFVVKPAGALRLQVALANAVALGRAAPPTTRPARTQPDNAQPDNVVAFTPASGPFVVAPPPL
RDSGTESPLPPLLRTESLAYARLDAAGHARRLEQIEAEAIRFACHLYGGRMAEVARRLGIGRSTLYRKLAELDADTVGGN
RDVEPDAARFVAAE
>Mature_253_residues
TLPLLLVEDDPVEARRLSSALAGLGYEVTLAEDGDAALDQLAAGTFDVVLLDLVVPGLDGMGVLDAMAARGLAVPVVVQV
TAAGLDAASGAIRAGARDFVVKPAGALRLQVALANAVALGRAAPPTTRPARTQPDNAQPDNVVAFTPASGPFVVAPPPLR
DSGTESPLPPLLRTESLAYARLDAAGHARRLEQIEAEAIRFACHLYGGRMAEVARRLGIGRSTLYRKLAELDADTVGGNR
DVEPDAARFVAAE

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=33.8983050847458, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=145, Percent_Identity=29.6551724137931, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 26326; Mature: 26195

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPLLLVEDDPVEARRLSSALAGLGYEVTLAEDGDAALDQLAAGTFDVVLLDLVVPGLD
CCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCC
GMGVLDAMAARGLAVPVVVQVTAAGLDAASGAIRAGARDFVVKPAGALRLQVALANAVAL
CCHHHHHHHHCCCCCEEEEEEECCCCCHHCCHHHCCCCCEEECCCCCEEEEHHHHHHHHH
GRAAPPTTRPARTQPDNAQPDNVVAFTPASGPFVVAPPPLRDSGTESPLPPLLRTESLAY
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHCCHHH
ARLDAAGHARRLEQIEAEAIRFACHLYGGRMAEVARRLGIGRSTLYRKLAELDADTVGGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
RDVEPDAARFVAAE
CCCCCCHHHEEECC
>Mature Secondary Structure 
TLPLLLVEDDPVEARRLSSALAGLGYEVTLAEDGDAALDQLAAGTFDVVLLDLVVPGLD
CCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCC
GMGVLDAMAARGLAVPVVVQVTAAGLDAASGAIRAGARDFVVKPAGALRLQVALANAVAL
CCHHHHHHHHCCCCCEEEEEEECCCCCHHCCHHHCCCCCEEECCCCCEEEEHHHHHHHHH
GRAAPPTTRPARTQPDNAQPDNVVAFTPASGPFVVAPPPLRDSGTESPLPPLLRTESLAY
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHCCHHH
ARLDAAGHARRLEQIEAEAIRFACHLYGGRMAEVARRLGIGRSTLYRKLAELDADTVGGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
RDVEPDAARFVAAE
CCCCCCHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]