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The map label for this gene is ribD [H]

Identifier: 154245980

GI number: 154245980

Start: 2295576

End: 2296424

Strand: Reverse

Name: ribD [H]

Synonym: Xaut_2037

Alternate gene names: 154245980

Gene position: 2296424-2295576 (Counterclockwise)

Preceding gene: 154245983

Following gene: 154245979

Centisome position: 43.26

GC content: 70.55

Gene sequence:

>849_bases
ATGGCGTTCCTGCTCCACATGCTCCATCTCTACGGCGGGCGAGAACCGATGGATGACACGACCCGGCGGCGGTCGCCGCA
TCAGGCGACGACCTCCCCTGAAGTGGCGATATATCATCCCATTCACAAGGGCGAACGGCCCTTCGTGGTGGCTCAGCTCG
GCCAGTCGCTGGACGGGCGGATCGCGACGCCCTCCGGCGAATCCAAATATATCAATGGCCCGCACGCCCTCGACCACCTG
CACGCCCTGCGCGCCGACGTGGACGCCGTGGTGGTGGGGGTCGGCACCGTTGTCGCCGACGACCCGCTGCTCACGGTCCG
CCGGGTGGCGGGCCGCAGCCCGGCACGGGTCATCATCGATCCCTCCGGCCGCGCCGATCCGGCCGCCCGCTGCTTCGCGC
CGGACGGCGCGCGCCGACTCGTCCTGCGCCGAACCGGGGTCGCCGCGCCCGTTGCCGAAGGGGTAGAAGTCGTTGCCATG
GAGGGGGCGGGCGCCTTCGAACCAGCAGCAATGCTGGACGCTCTTGCCGCCCGCGGCCTGACCCGCATCCTGGTGGAGGG
CGGGGCGCACACGCTCTCGGCCTTCCTGGAGGCCGGATGCCTTGATGCCCTTCACGTTTTCGTGTCCCCGGTCATCCTCG
GCGCCGGCCGGATCGGACTGACGCGCAAGGCGTGCGACACTCTGGCTGACGCCTTGCGGCCCGCCGCGCGGGCGCATGTG
TTTCCGGACGGGGACGTGCTGTTCGCGTGCGATCTCGCCCGAGCCGGGGAGGCCCAAGCCGACGATGCCCAATCCAGAAA
TTCCCAATCAAACCCCGCCCGCACCCGCCGCCTACGGGCGGCCGGCTAG

Upstream 100 bases:

>100_bases
AACCACCGTTGTCATGAAGACCCCTTACAGGCAGAGGCGGCGCCGCAATGCGCCAGAAAAAGATCCACAAACGCAGCAGG
GTCGTAACAAACGACGGCGT

Downstream 100 bases:

>100_bases
GGCGCTGCACTGGATCATGGCGCTGCTGGTCCTCGCCGTGATCCCCGCCGGCTTCACCATGATGAACCTGCCGTCGGGGC
CGGCGCAGGACTGGTTCTTC

Product: deaminase-reductase domain-containing protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MAFLLHMLHLYGGREPMDDTTRRRSPHQATTSPEVAIYHPIHKGERPFVVAQLGQSLDGRIATPSGESKYINGPHALDHL
HALRADVDAVVVGVGTVVADDPLLTVRRVAGRSPARVIIDPSGRADPAARCFAPDGARRLVLRRTGVAAPVAEGVEVVAM
EGAGAFEPAAMLDALAARGLTRILVEGGAHTLSAFLEAGCLDALHVFVSPVILGAGRIGLTRKACDTLADALRPAARAHV
FPDGDVLFACDLARAGEAQADDAQSRNSQSNPARTRRLRAAG

Sequences:

>Translated_282_residues
MAFLLHMLHLYGGREPMDDTTRRRSPHQATTSPEVAIYHPIHKGERPFVVAQLGQSLDGRIATPSGESKYINGPHALDHL
HALRADVDAVVVGVGTVVADDPLLTVRRVAGRSPARVIIDPSGRADPAARCFAPDGARRLVLRRTGVAAPVAEGVEVVAM
EGAGAFEPAAMLDALAARGLTRILVEGGAHTLSAFLEAGCLDALHVFVSPVILGAGRIGLTRKACDTLADALRPAARAHV
FPDGDVLFACDLARAGEAQADDAQSRNSQSNPARTRRLRAAG
>Mature_281_residues
AFLLHMLHLYGGREPMDDTTRRRSPHQATTSPEVAIYHPIHKGERPFVVAQLGQSLDGRIATPSGESKYINGPHALDHLH
ALRADVDAVVVGVGTVVADDPLLTVRRVAGRSPARVIIDPSGRADPAARCFAPDGARRLVLRRTGVAAPVAEGVEVVAME
GAGAFEPAAMLDALAARGLTRILVEGGAHTLSAFLEAGCLDALHVFVSPVILGAGRIGLTRKACDTLADALRPAARAHVF
PDGDVLFACDLARAGEAQADDAQSRNSQSNPARTRRLRAAG

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=214, Percent_Identity=32.7102803738318, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 29677; Mature: 29546

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLLHMLHLYGGREPMDDTTRRRSPHQATTSPEVAIYHPIHKGERPFVVAQLGQSLDGR
CHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEHEECCCCCCCE
IATPSGESKYINGPHALDHLHALRADVDAVVVGVGTVVADDPLLTVRRVAGRSPARVIID
EECCCCCCCCCCCCHHHHHHHHHHHCHHEEEEECCHHCCCCCHHHHHHHHCCCCCEEEEC
PSGRADPAARCFAPDGARRLVLRRTGVAAPVAEGVEVVAMEGAGAFEPAAMLDALAARGL
CCCCCCCCCEECCCCCHHEEHHHHCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHHHCCH
TRILVEGGAHTLSAFLEAGCLDALHVFVSPVILGAGRIGLTRKACDTLADALRPAARAHV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
FPDGDVLFACDLARAGEAQADDAQSRNSQSNPARTRRLRAAG
CCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
AFLLHMLHLYGGREPMDDTTRRRSPHQATTSPEVAIYHPIHKGERPFVVAQLGQSLDGR
HHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEHEECCCCCCCE
IATPSGESKYINGPHALDHLHALRADVDAVVVGVGTVVADDPLLTVRRVAGRSPARVIID
EECCCCCCCCCCCCHHHHHHHHHHHCHHEEEEECCHHCCCCCHHHHHHHHCCCCCEEEEC
PSGRADPAARCFAPDGARRLVLRRTGVAAPVAEGVEVVAMEGAGAFEPAAMLDALAARGL
CCCCCCCCCEECCCCCHHEEHHHHCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHHHCCH
TRILVEGGAHTLSAFLEAGCLDALHVFVSPVILGAGRIGLTRKACDTLADALRPAARAHV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
FPDGDVLFACDLARAGEAQADDAQSRNSQSNPARTRRLRAAG
CCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]