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The map label for this gene is ctpC [H]

Identifier: 154245955

GI number: 154245955

Start: 2269447

End: 2271336

Strand: Direct

Name: ctpC [H]

Synonym: Xaut_2012

Alternate gene names: 154245955

Gene position: 2269447-2271336 (Clockwise)

Preceding gene: 154245952

Following gene: 154245958

Centisome position: 42.75

GC content: 74.87

Gene sequence:

>1890_bases
ATGCCCGGGGCGGCACGGACTGTGATGGGCGTCGGCCTGGCGCGCAACCGCTACCTCCTGCTCACGGCGGCCGTGCTGCC
GCTGGTCACCGGCCTCGGCCTGCTGGTGGCGGGGCAGGATCGCGCGGCGTTCTTTGCCTTCGTGGCCGGCACCGTGCCGG
TGCTCGCGGTGCTGGTGTTCGACATCGCGCGGGCGCTGGGGGAAGGCCGGTTCGGCCTCGACCTGCTGGCGGCCCTGTCC
ATGGCCACGGCGCTGGCCTTCGGCGAGCCGCTGGCGGGTAACGTGGTCGCCCTGATGTATGCCGGCGGCCAGCAACTGGA
GCGCTTCGCCGAGGGCCGCGCCCGGAGGGAGATGACCGCGCTCGCCGCCCGCGCCCCCCGCTCGGCCCTGCTGCGGGAGG
GCGACACGCTCCGGGAGGTGCCCATCGGCGCGCTGAAGGCGGGCAACCTCATCGTGGTGCGGCAGGGCGACACGATCCCC
GCCGACGGGCGCATCTGCGGCGGGCCGGCGGTGCTCGACCAGTCCTCCCTGACAGGTGAGGCGCACCCGGTGCGGCTGGA
GGAGGGGGAGGAGGCGCCGTCGGGCGCCGTCAACGTGGGCGGCGCCTTCGACGTGCGGGTGCTCAGGTCCGCGGATGAGA
GCACCTATGCGGCCATCGTGCGTCTTGTAGAGGCGGCGGCCGCCAGCCGCGCCCCCATGGCGCGCCTCGCCGATCGCTAT
GCGCTCGGCTTCCTGGTGGTGTCGCTGGGGCTGGCGCTGGCTGCGGCGTTCCTCTCCGGCGATCCGCGCCGGGCTTTGGC
GGTGCTGGTGGTGGCGACCCCGTGCCCGCTCATCCTCGCGGTGCCGGTGGCGCTCATGGCCGGCCTGTCGCGGGCCGCCA
AACGCGGCGTGCTGGTGAAGAGCGGCGGCGCGCTGGAGAAGCTGGCCGCCGTGCGGGCGCTGGTGATCGACAAGACCGGG
ACCCTCACCCACGGCAGGGCCCAGCTTCAGGAGATCCGCACCGCGCCGGACTTCGCCCCCGACGAGGTGTTGCGCCTTGC
CGCCGCCCTCGACCAGGCCTCCAGCCATGTGGTGGCGGCGGCTCTGGTGGCGGCGGCCAAAGCCCGCGGCCTCGCCCTCG
CCGTGCCGGAGGGCGTGGCGGAAGAGGGCGGCGTCGGTGTCACCGGGCGGGTGGAAGGCCGGGAGGTGGCCGTGGGCGGC
TGCAGTTTCGTCGCGGCGCGGGCCACCAGCGACGGGGACGCCCTGCGTGCCTGCCTGCCGGCGGCGAGCGCGGTGGTCGC
GGTCGGCATCGACGGATGCTTTGCCGGCCTGCTCATTCTCGCCGACCAGGTGCGGGACGATGCGGGGGAGATGGTGCGGG
CCCTTCGGGCCGGCGGGGTGGACCACATCGTCCTCGCTTCGGGCGACCGCGCGGAAGCGGTGGAGGCGTTGGGCCGCAGC
CTCGGCCTCGACAGCTGGGTGGGCGACCTTCAGCCCGGCGGCAAGGTCTCCCACGTCACCGATGCCCGTGCCCGCGCCCA
TGCCCGGCGCGACTCGGGCACGGTGATGATGGTGGGCGACGGGGTCAACGACGCCCCGGCTTTGGCCGCTGCCGATGTGG
GCGTGGCGCTGGGCGCGCGCGGCGCCGCCGCCTCTGCCGAGGTGGCGGACGTGGTGCTGCTGGTGGACCGGCTGGATCGG
CTCGGCGAGGCCATGGCCATTGCCCGACGGGCGCTCGCCATCGCACGGCAGAGCGTGTTCGTGGGCATCGCCCTGTCGCT
CATCGGCATGCTGGCGGCCGCCTTCGGCTTTCTGGAGCCGGTGGCCGGCGCCCTGCTGCAGGAGGCCATCGACGTGGCGG
TGATCCTCAACGCCCTCCGGGTGCTGATCCCCGGGCCGGGGGAGGGGTGA

Upstream 100 bases:

>100_bases
CCAAATTAGAATATTTCTAATATCAATAGACGAACGATATCCGCAACGGCAATGCGACCGCATGGCCAAACGCCGGATGG
CTACCGGCGAGGAGAGATGC

Downstream 100 bases:

>100_bases
GGGCGCACCCACCGGGCATTGCTTGAATAAAAAAAGGCCGATGGCATGAGGCATGAAAAAGCCGGCCGCCCCTTCGGACG
GCCGGCCCTTTATCGGTCGC

Product: heavy metal translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MPGAARTVMGVGLARNRYLLLTAAVLPLVTGLGLLVAGQDRAAFFAFVAGTVPVLAVLVFDIARALGEGRFGLDLLAALS
MATALAFGEPLAGNVVALMYAGGQQLERFAEGRARREMTALAARAPRSALLREGDTLREVPIGALKAGNLIVVRQGDTIP
ADGRICGGPAVLDQSSLTGEAHPVRLEEGEEAPSGAVNVGGAFDVRVLRSADESTYAAIVRLVEAAAASRAPMARLADRY
ALGFLVVSLGLALAAAFLSGDPRRALAVLVVATPCPLILAVPVALMAGLSRAAKRGVLVKSGGALEKLAAVRALVIDKTG
TLTHGRAQLQEIRTAPDFAPDEVLRLAAALDQASSHVVAAALVAAAKARGLALAVPEGVAEEGGVGVTGRVEGREVAVGG
CSFVAARATSDGDALRACLPAASAVVAVGIDGCFAGLLILADQVRDDAGEMVRALRAGGVDHIVLASGDRAEAVEALGRS
LGLDSWVGDLQPGGKVSHVTDARARAHARRDSGTVMMVGDGVNDAPALAAADVGVALGARGAAASAEVADVVLLVDRLDR
LGEAMAIARRALAIARQSVFVGIALSLIGMLAAAFGFLEPVAGALLQEAIDVAVILNALRVLIPGPGEG

Sequences:

>Translated_629_residues
MPGAARTVMGVGLARNRYLLLTAAVLPLVTGLGLLVAGQDRAAFFAFVAGTVPVLAVLVFDIARALGEGRFGLDLLAALS
MATALAFGEPLAGNVVALMYAGGQQLERFAEGRARREMTALAARAPRSALLREGDTLREVPIGALKAGNLIVVRQGDTIP
ADGRICGGPAVLDQSSLTGEAHPVRLEEGEEAPSGAVNVGGAFDVRVLRSADESTYAAIVRLVEAAAASRAPMARLADRY
ALGFLVVSLGLALAAAFLSGDPRRALAVLVVATPCPLILAVPVALMAGLSRAAKRGVLVKSGGALEKLAAVRALVIDKTG
TLTHGRAQLQEIRTAPDFAPDEVLRLAAALDQASSHVVAAALVAAAKARGLALAVPEGVAEEGGVGVTGRVEGREVAVGG
CSFVAARATSDGDALRACLPAASAVVAVGIDGCFAGLLILADQVRDDAGEMVRALRAGGVDHIVLASGDRAEAVEALGRS
LGLDSWVGDLQPGGKVSHVTDARARAHARRDSGTVMMVGDGVNDAPALAAADVGVALGARGAAASAEVADVVLLVDRLDR
LGEAMAIARRALAIARQSVFVGIALSLIGMLAAAFGFLEPVAGALLQEAIDVAVILNALRVLIPGPGEG
>Mature_628_residues
PGAARTVMGVGLARNRYLLLTAAVLPLVTGLGLLVAGQDRAAFFAFVAGTVPVLAVLVFDIARALGEGRFGLDLLAALSM
ATALAFGEPLAGNVVALMYAGGQQLERFAEGRARREMTALAARAPRSALLREGDTLREVPIGALKAGNLIVVRQGDTIPA
DGRICGGPAVLDQSSLTGEAHPVRLEEGEEAPSGAVNVGGAFDVRVLRSADESTYAAIVRLVEAAAASRAPMARLADRYA
LGFLVVSLGLALAAAFLSGDPRRALAVLVVATPCPLILAVPVALMAGLSRAAKRGVLVKSGGALEKLAAVRALVIDKTGT
LTHGRAQLQEIRTAPDFAPDEVLRLAAALDQASSHVVAAALVAAAKARGLALAVPEGVAEEGGVGVTGRVEGREVAVGGC
SFVAARATSDGDALRACLPAASAVVAVGIDGCFAGLLILADQVRDDAGEMVRALRAGGVDHIVLASGDRAEAVEALGRSL
GLDSWVGDLQPGGKVSHVTDARARAHARRDSGTVMMVGDGVNDAPALAAADVGVALGARGAAASAEVADVVLLVDRLDRL
GEAMAIARRALAIARQSVFVGIALSLIGMLAAAFGFLEPVAGALLQEAIDVAVILNALRVLIPGPGEG

Specific function: Involved In Export Of Lead, Cadmium, Zinc And Mercury. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=663, Percent_Identity=26.0935143288084, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI55743071, Length=335, Percent_Identity=28.6567164179104, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI55743073, Length=196, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI83700225, Length=238, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4502271, Length=309, Percent_Identity=26.2135922330097, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI297374799, Length=244, Percent_Identity=25.4098360655738, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI22748667, Length=301, Percent_Identity=24.9169435215947, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI153946397, Length=239, Percent_Identity=25.5230125523013, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI118498343, Length=254, Percent_Identity=25.5905511811024, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI237681111, Length=249, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI21361181, Length=249, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI237681109, Length=249, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI1789879, Length=618, Percent_Identity=32.2006472491909, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1786691, Length=548, Percent_Identity=32.4817518248175, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1786914, Length=511, Percent_Identity=27.2015655577299, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI2367363, Length=287, Percent_Identity=29.2682926829268, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17556548, Length=650, Percent_Identity=26.4615384615385, Blast_Score=148, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17559224, Length=248, Percent_Identity=25.4032258064516, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997262, Length=254, Percent_Identity=27.5590551181102, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997275, Length=254, Percent_Identity=27.5590551181102, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997269, Length=254, Percent_Identity=27.5590551181102, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=544, Percent_Identity=27.5735294117647, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319772, Length=574, Percent_Identity=25.4355400696864, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321430, Length=560, Percent_Identity=26.7857142857143, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6325221, Length=584, Percent_Identity=26.541095890411, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221329854, Length=416, Percent_Identity=29.0865384615385, Blast_Score=129, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.3 [C]

Molecular weight: Translated: 63610; Mature: 63478

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGAARTVMGVGLARNRYLLLTAAVLPLVTGLGLLVAGQDRAAFFAFVAGTVPVLAVLVF
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
DIARALGEGRFGLDLLAALSMATALAFGEPLAGNVVALMYAGGQQLERFAEGRARREMTA
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
LAARAPRSALLREGDTLREVPIGALKAGNLIVVRQGDTIPADGRICGGPAVLDQSSLTGE
HHHHCCHHHHHHCCCCHHHCCCCEECCCCEEEEECCCCCCCCCEEECCCHHCCCCCCCCC
AHPVRLEEGEEAPSGAVNVGGAFDVRVLRSADESTYAAIVRLVEAAAASRAPMARLADRY
CCCEECCCCCCCCCCCEECCCCEEHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALGFLVVSLGLALAAAFLSGDPRRALAVLVVATPCPLILAVPVALMAGLSRAAKRGVLVK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEE
SGGALEKLAAVRALVIDKTGTLTHGRAQLQEIRTAPDFAPDEVLRLAAALDQASSHVVAA
CCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALVAAAKARGLALAVPEGVAEEGGVGVTGRVEGREVAVGGCSFVAARATSDGDALRACLP
HHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCEEEECCCCEEEEECCCCHHHHHHHHH
AASAVVAVGIDGCFAGLLILADQVRDDAGEMVRALRAGGVDHIVLASGDRAEAVEALGRS
HHHHHEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
LGLDSWVGDLQPGGKVSHVTDARARAHARRDSGTVMMVGDGVNDAPALAAADVGVALGAR
CCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
GAAASAEVADVVLLVDRLDRLGEAMAIARRALAIARQSVFVGIALSLIGMLAAAFGFLEP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGALLQEAIDVAVILNALRVLIPGPGEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PGAARTVMGVGLARNRYLLLTAAVLPLVTGLGLLVAGQDRAAFFAFVAGTVPVLAVLVF
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
DIARALGEGRFGLDLLAALSMATALAFGEPLAGNVVALMYAGGQQLERFAEGRARREMTA
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
LAARAPRSALLREGDTLREVPIGALKAGNLIVVRQGDTIPADGRICGGPAVLDQSSLTGE
HHHHCCHHHHHHCCCCHHHCCCCEECCCCEEEEECCCCCCCCCEEECCCHHCCCCCCCCC
AHPVRLEEGEEAPSGAVNVGGAFDVRVLRSADESTYAAIVRLVEAAAASRAPMARLADRY
CCCEECCCCCCCCCCCEECCCCEEHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALGFLVVSLGLALAAAFLSGDPRRALAVLVVATPCPLILAVPVALMAGLSRAAKRGVLVK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEE
SGGALEKLAAVRALVIDKTGTLTHGRAQLQEIRTAPDFAPDEVLRLAAALDQASSHVVAA
CCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALVAAAKARGLALAVPEGVAEEGGVGVTGRVEGREVAVGGCSFVAARATSDGDALRACLP
HHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCEEEECCCCEEEEECCCCHHHHHHHHH
AASAVVAVGIDGCFAGLLILADQVRDDAGEMVRALRAGGVDHIVLASGDRAEAVEALGRS
HHHHHEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
LGLDSWVGDLQPGGKVSHVTDARARAHARRDSGTVMMVGDGVNDAPALAAADVGVALGAR
CCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
GAAASAEVADVVLLVDRLDRLGEAMAIARRALAIARQSVFVGIALSLIGMLAAAFGFLEP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGALLQEAIDVAVILNALRVLIPGPGEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]