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The map label for this gene is slyA [H]

Identifier: 154245932

GI number: 154245932

Start: 2246412

End: 2246906

Strand: Direct

Name: slyA [H]

Synonym: Xaut_1989

Alternate gene names: 154245932

Gene position: 2246412-2246906 (Clockwise)

Preceding gene: 154245929

Following gene: 154245933

Centisome position: 42.31

GC content: 71.31

Gene sequence:

>495_bases
ATGGCTGCTCCGTCTCCCACTCCCGTCGCCGCCCCGCGCCCCGCGCCGAGCGAACCGCCCCTTGGCTTCGTCCTCGTGGA
TGCGGCGCGGCTTTATCGTGCGCGGATCGACCGGGCCTTCGAGGGCGCCGGCCTTGGCCTCACCGCCGGGGAGGCGCGCA
CGCTGGCCTATGTGGATTTCCATCCAGGCCTCAGGCAATCGGCGCTGGCCGAGAAGATGAATGTGGAGCCCATGACCCTG
GTGGGCTTCCTCGACCGGCTGGAGGCCGCCGGCCTCGTCACCCGCGAAACCGACCCGAAGGACCGCCGCGCCAAGATCGT
GGCGCTCACGCCCGAGGCGACGCCCTACCTTGCCGGGGTGCTCTCTGCGGCGGCCACCGCGCGAGGTGAGGCCACCTGCG
GCTTCACGGACGCCGAGCAGGCTCTGCTGCGGGACCTGCTGCTGCGGCTGCGCGACAACCTCGCGCGGGAGCATCGCTTG
AGGGACGAGAAATGA

Upstream 100 bases:

>100_bases
GGAGACAGGTGAGCGAACCGGCCCCTCATCCCGATTTCATCCCGCAGGCGGGCATCTCTCCCTTGATAGTAAGGTTTACT
GACTATATTGTCACCTTATC

Downstream 100 bases:

>100_bases
GCGCCGTCCCGCACAGAACCGCCCCTGCGCCGGCCGTCGGGGTTTCGGCCGCGCCGCTCATGAGCGAGCGGGAAGTGTCC
GTCATCGGCGCGCTCATGGT

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MAAPSPTPVAAPRPAPSEPPLGFVLVDAARLYRARIDRAFEGAGLGLTAGEARTLAYVDFHPGLRQSALAEKMNVEPMTL
VGFLDRLEAAGLVTRETDPKDRRAKIVALTPEATPYLAGVLSAAATARGEATCGFTDAEQALLRDLLLRLRDNLAREHRL
RDEK

Sequences:

>Translated_164_residues
MAAPSPTPVAAPRPAPSEPPLGFVLVDAARLYRARIDRAFEGAGLGLTAGEARTLAYVDFHPGLRQSALAEKMNVEPMTL
VGFLDRLEAAGLVTRETDPKDRRAKIVALTPEATPYLAGVLSAAATARGEATCGFTDAEQALLRDLLLRLRDNLAREHRL
RDEK
>Mature_163_residues
AAPSPTPVAAPRPAPSEPPLGFVLVDAARLYRARIDRAFEGAGLGLTAGEARTLAYVDFHPGLRQSALAEKMNVEPMTLV
GFLDRLEAAGLVTRETDPKDRRAKIVALTPEATPYLAGVLSAAATARGEATCGFTDAEQALLRDLLLRLRDNLAREHRLR
DEK

Specific function: Transcription regulator that either activates or represses expression of target genes. Required to activate expression of virulent genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=138, Percent_Identity=34.0579710144928, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17656; Mature: 17525

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPSPTPVAAPRPAPSEPPLGFVLVDAARLYRARIDRAFEGAGLGLTAGEARTLAYVDF
CCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEEC
HPGLRQSALAEKMNVEPMTLVGFLDRLEAAGLVTRETDPKDRRAKIVALTPEATPYLAGV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCHHHHHH
LSAAATARGEATCGFTDAEQALLRDLLLRLRDNLAREHRLRDEK
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAPSPTPVAAPRPAPSEPPLGFVLVDAARLYRARIDRAFEGAGLGLTAGEARTLAYVDF
CCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEEC
HPGLRQSALAEKMNVEPMTLVGFLDRLEAAGLVTRETDPKDRRAKIVALTPEATPYLAGV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCHHHHHH
LSAAATARGEATCGFTDAEQALLRDLLLRLRDNLAREHRLRDEK
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10385201; 11939575 [H]