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The map label for this gene is metX

Identifier: 154245853

GI number: 154245853

Start: 2158995

End: 2160215

Strand: Direct

Name: metX

Synonym: Xaut_1909

Alternate gene names: 154245853

Gene position: 2158995-2160215 (Clockwise)

Preceding gene: 154245847

Following gene: 154245854

Centisome position: 40.67

GC content: 68.22

Gene sequence:

>1221_bases
ATGACTTCTTTCGTCCAACAGGATGTCGCCCTGCAAGACTCCGCCGGAGCCTCCGTCCTCCAGGCGCGGCGCGAGGCGGA
CGACCCCCACTCCCCGGTGGCGCGCTTCGGCGCCCGCAACCCGCTCAAGCTCGACGCGGGGGTGGAGCTGTCGCACCTGC
AGATCGCCTACCAGACCTATGGCGAGCCCAATGCCGCACGCTCCAACGCCATCCTGGTGTGCCACGCGCTGACCGGCGAC
CAGCATGCGGCCAGCCTCAATCCCGTCACCGGCAAGCCGGGCTGGTGGGAGACGCTGGTCGGCCCCGGCAAGCCCATCGA
CACCGAGCGCTTCTACGTCATCTGCGCCAATGTGCTCGGCGGCTGCATGGGCACCACCGGGCCGGCCTCCACCAATCCCC
TGACCGGCCAGCCCTATGGGCTCGACATGCCGGTGGTGACCATCCGCGACATGGTCAACGCCCAGGCCATGCTGCTGGAT
CACCTCGGCATCGACAAGCTGTTGTGCGTGGCTGGCGGCTCCATGGGCGGCATGCAGGTGCTGCAATGGGCGGCGAGCTA
TCCCGAGCGGGTGTTCTCGGCCCTGCCCATTGCCACCGGCGCGCGCCATTCGGCGCAGAACATCGCCTTCCACGAGGTGG
GCCGGCAGGCGGTGATGGCCGATCCCGACTGGCGCGGCGGGCGCTATCTCGCGGAGGGGGTGACGCCCCATCGCGGGCTC
GCCGTGGCGCGCATGGCGGCCCACATCACCTACATGTCGGACCAGTCCCTGCACAACAAGTTCGGCCGGCGCCTGCAGAA
CCGCGACATGCCCACCTTCGGCTTCGATGCCGACTTCCAGGTGGAAAGCTATCTGCGGCACCAGGGCGAAAGCTTCGTGC
AGCGCTTCGATCCCAACTCCTATCTCTACGTGACCCGCGCCATGGATTATTTCGACCTCGCCGCCGACCATGGCGGCGTG
CTGGCCAATGCCTTCCGGGGCTCGAAGACGCGCTTCTGCGTGGTCTCCTTCACCTCGGACTGGCTGTTCCCCACCGAGGA
TTCGCGCGCCATCGTCCATGCGCTCAACGCCTCGGGAGCGAACGTGTCCTTCACCGAGATCGATAGCGACAAGGGCCACG
ACGCCTTCCTGCTGCACGAGCCGGAGCTGACCGCCATCACCCGCGGCTTCCTCGACAGCGCGGCGCGGGCCTTCGGCCTG
CCGGCGGCACGGCAGGCCTGA

Upstream 100 bases:

>100_bases
CGCTGCACGGCTTTCTGCCGCGCGCGGCCTGTTCCGCTCCGTTTCCACGGTGCCTGTGCCTGCGCTTGACAGGTGCGCGC
CCGCGTCGCTTGGTTCGCCC

Downstream 100 bases:

>100_bases
GATGGCGCTCAGCGAACCGGTGCTGGACGAGGGCGTGGTGCGCCTGCAGGGCGGGCGCGTCGATCTCGTGGTCGTGGCGG
AGATGGTGGCGCCGGGCTCG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTSFVQQDVALQDSAGASVLQARREADDPHSPVARFGARNPLKLDAGVELSHLQIAYQTYGEPNAARSNAILVCHALTGD
QHAASLNPVTGKPGWWETLVGPGKPIDTERFYVICANVLGGCMGTTGPASTNPLTGQPYGLDMPVVTIRDMVNAQAMLLD
HLGIDKLLCVAGGSMGGMQVLQWAASYPERVFSALPIATGARHSAQNIAFHEVGRQAVMADPDWRGGRYLAEGVTPHRGL
AVARMAAHITYMSDQSLHNKFGRRLQNRDMPTFGFDADFQVESYLRHQGESFVQRFDPNSYLYVTRAMDYFDLAADHGGV
LANAFRGSKTRFCVVSFTSDWLFPTEDSRAIVHALNASGANVSFTEIDSDKGHDAFLLHEPELTAITRGFLDSAARAFGL
PAARQA

Sequences:

>Translated_406_residues
MTSFVQQDVALQDSAGASVLQARREADDPHSPVARFGARNPLKLDAGVELSHLQIAYQTYGEPNAARSNAILVCHALTGD
QHAASLNPVTGKPGWWETLVGPGKPIDTERFYVICANVLGGCMGTTGPASTNPLTGQPYGLDMPVVTIRDMVNAQAMLLD
HLGIDKLLCVAGGSMGGMQVLQWAASYPERVFSALPIATGARHSAQNIAFHEVGRQAVMADPDWRGGRYLAEGVTPHRGL
AVARMAAHITYMSDQSLHNKFGRRLQNRDMPTFGFDADFQVESYLRHQGESFVQRFDPNSYLYVTRAMDYFDLAADHGGV
LANAFRGSKTRFCVVSFTSDWLFPTEDSRAIVHALNASGANVSFTEIDSDKGHDAFLLHEPELTAITRGFLDSAARAFGL
PAARQA
>Mature_405_residues
TSFVQQDVALQDSAGASVLQARREADDPHSPVARFGARNPLKLDAGVELSHLQIAYQTYGEPNAARSNAILVCHALTGDQ
HAASLNPVTGKPGWWETLVGPGKPIDTERFYVICANVLGGCMGTTGPASTNPLTGQPYGLDMPVVTIRDMVNAQAMLLDH
LGIDKLLCVAGGSMGGMQVLQWAASYPERVFSALPIATGARHSAQNIAFHEVGRQAVMADPDWRGGRYLAEGVTPHRGLA
VARMAAHITYMSDQSLHNKFGRRLQNRDMPTFGFDADFQVESYLRHQGESFVQRFDPNSYLYVTRAMDYFDLAADHGGVL
ANAFRGSKTRFCVVSFTSDWLFPTEDSRAIVHALNASGANVSFTEIDSDKGHDAFLLHEPELTAITRGFLDSAARAFGLP
AARQA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=224, Percent_Identity=41.9642857142857, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 44025; Mature: 43894

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFVQQDVALQDSAGASVLQARREADDPHSPVARFGARNPLKLDAGVELSHLQIAYQTY
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCEEECCCCEEHHEEEEEECC
GEPNAARSNAILVCHALTGDQHAASLNPVTGKPGWWETLVGPGKPIDTERFYVICANVLG
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEHHHHH
GCMGTTGPASTNPLTGQPYGLDMPVVTIRDMVNAQAMLLDHLGIDKLLCVAGGSMGGMQV
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCHHHH
LQWAASYPERVFSALPIATGARHSAQNIAFHEVGRQAVMADPDWRGGRYLAEGVTPHRGL
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHH
AVARMAAHITYMSDQSLHNKFGRRLQNRDMPTFGFDADFQVESYLRHQGESFVQRFDPNS
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCC
YLYVTRAMDYFDLAADHGGVLANAFRGSKTRFCVVSFTSDWLFPTEDSRAIVHALNASGA
EEEEEECCHHHHHHCCCCCEEEHHCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCC
NVSFTEIDSDKGHDAFLLHEPELTAITRGFLDSAARAFGLPAARQA
CEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSFVQQDVALQDSAGASVLQARREADDPHSPVARFGARNPLKLDAGVELSHLQIAYQTY
CCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCEEECCCCEEHHEEEEEECC
GEPNAARSNAILVCHALTGDQHAASLNPVTGKPGWWETLVGPGKPIDTERFYVICANVLG
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEHHHHH
GCMGTTGPASTNPLTGQPYGLDMPVVTIRDMVNAQAMLLDHLGIDKLLCVAGGSMGGMQV
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCHHHH
LQWAASYPERVFSALPIATGARHSAQNIAFHEVGRQAVMADPDWRGGRYLAEGVTPHRGL
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHH
AVARMAAHITYMSDQSLHNKFGRRLQNRDMPTFGFDADFQVESYLRHQGESFVQRFDPNS
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCC
YLYVTRAMDYFDLAADHGGVLANAFRGSKTRFCVVSFTSDWLFPTEDSRAIVHALNASGA
EEEEEECCHHHHHHCCCCCEEEHHCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCC
NVSFTEIDSDKGHDAFLLHEPELTAITRGFLDSAARAFGLPAARQA
CEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]