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The map label for this gene is speF [H]

Identifier: 154244592

GI number: 154244592

Start: 718948

End: 721305

Strand: Reverse

Name: speF [H]

Synonym: Xaut_0640

Alternate gene names: 154244592

Gene position: 721305-718948 (Counterclockwise)

Preceding gene: 154244593

Following gene: 154244591

Centisome position: 13.59

GC content: 66.12

Gene sequence:

>2358_bases
ATGGACTATTTCAAGCGATTCAACTTCCTGTTCGCGACCCCGGTGTTCGACGCCGAGGATCTGGAGGGCGCCCGCTACAA
CCAGATCGTCGCGGAGATCGAGCGTTCCGGCTTCGAGGTGGTGAAGGCGCGCAACCTCGAAGACGCCGAGATCGCGGTGC
AGACCGATGCCGCCATCGGCTGCATGCTGGTGGACTGGGGCAAGAAGGGGCTGGAGGGCAAGACCGCCGCCCTCATCAAC
CTGATGCGCCGGCGCGGCCTCGACTTCCCCATCCTCCTGCTGATCCGCCGCAAGCGCTTCGAGGATGTGCCGGTGGAGGT
GCTGGACTTCATCGACGGCTACGTCTTCCTCTCCGAGGAAACCCCCGCCTTCATCGCCAAGAACCTCATCAGCCGGCTCA
AGCAATATGCCGAGACGCTGAAGACCCCCTTCTTCGGCGCGCTGGTGGACTATGCCGAAGAGGGCAACCAGCTGTGGACC
TGCCCCGGGCACAATGGCGGCGTGTTCTATTCCCGCAGCCCCATCGGCCGGGTGTTCATGGAGCATCTGGGCGAGGCGGT
GTTCCGCGACGACCTCGACAATTCCGTGCTCGACCTCGGCGACCTCCTGACCCACGAGGGCCCGGCGCTGGCGGCGCAGA
AGGAGGCGGCGAAGATCTTCGGCGCCGAGAAGACCTATTTCGTCCTCAACGGCACCTCCACCTCCAACAAGGTTGCGCTT
TCGGCCCTCGTCACCGACGGCGACCTGGTGCTGTTCGACCGCAACAACCACAAGGCCGCCCACCACGGCGCGCTGATGAT
CTCCGGCGGCATCCCGGTCTATGTGCCCACCGTGCGCAACGCCCATGGCCTCATCGGCCCCATGGACTTCGCCGCGCTGG
ACGAGACCGCCCTGCGCGAGCGCATCCGCACCCATCCCCTGGTGAAGGATCCGGACGCGTGGCAGAAACCGCGCCCGTTC
CGGGTGGCGGTGGTGGAGCAGTGCACCTATGACGGCACCATCCACAATGCCGAGATGATCCTCAAGGCCATCGGCCACCT
CACCGACTACATCCTGTTCGACGAGGCCTGGGCGGGCTTCATGAAGTTCCACCCGCTCTATGCCGGCCGCTTCGCCATGG
GCCTTGCCGACCTCGGCCCCGACGCGCCGGGCATCATCGCCACCCAGTCGACCCACAAGCAGCTGGCGAGCTTCTCGCAG
GCCTCCCAGATCCACATGAAGGACCGGCACATCACCGGCCAGAAGCGGCGGGTGGAGCACCGGCGCTTCAACGAGAGCTT
CATGCAGCACGCCTCCACCTCGCCCTTCTATCCCTTGTTCGCCTCCCTCGACGTGGGCGCGCAGATGATGAAGGGCCGGT
CCGGTGAAGTGCTGTGGGACGACACCATCCGCCTCGGCATCGAGCTCAGGAAGAAGATCCGAGCCGTGCGCCGCGAGTTC
GAGGAGAAGGAGCTTCGCCCCGAGCGCCGCTGGTTCTTCGAGCCGTTCGTGCCGGACCGGGTGGCCATCCCCGACGTGTC
GAGCCCCGGCGCGGTGCATGAGGTGCCGTGGGAAAGCGTCGCCACCGATCTCCTCGCCACCAACCCCGCCTTCTGGCACC
TGACCCCCGGCGCGTCCTGGCATGGCTTCGAGGGCATGGCGGCGGGTTTCGCCATGACCGACCCCAACAAGCTGACCCTT
CTGACCCCCGGCTTCGACCGCGCCACCGGCGCCTATGCCGAGCACGGCATCCCGGCGCCCGTGGTGGCGCAATATCTGCG
CGAGAACCGCATCGTCGCCGAGAAGAACGACCTTAATTCCCTGCTGTTCCTGCTCACCCCTGGGGTGGAGGCATCGAAGG
CGGGCACGCTCATCTCCGGCCTCGTCGCCTTCAAGAAGCTGCATGACGAGAATGCGCTTCTGGAAGAGGCGATCCCGGAA
TTTTTCCGCCGTCGTCCCGCCCGCTATGGGGGCGTGCGGCTGCGCGACCTGTGCGGGGAGATGCACCGCTTCTTCCGCGC
CGCGAATGTGAGCGCACTCCAGGCCATGCAATTTTCCGCCGCGCACCTGCCGGACATCGCGCTGTCGCCCCACGACGCGG
CCCGCTGCCTGGTGCGCAACGACGTGGACTACCTGCCCATCGACGCCATCTCCGGCCGCATCGCGACCACGCCCTTCGTG
GTCTATCCGCCGGGCATCGCCACCATCGTGCCGGGCGAGCGGCTGACCGAGCGGGCCAAGCCCATGATCGACTATCTCAA
GATGTTCGAAGCGAGCTTCAACACCTTCCCCGGCTTCGACGTGGAGATCCAGGGCCTGTATCGCGAGACGGATGCATCCG
GCCGCGTGCGGCTCCATACTTACGTCGTCGCGGAATAG

Upstream 100 bases:

>100_bases
GGGGCAGGAGCGGGGGCGGACGGAGGATGGCCACACTTCTGTCGCCGGCTTGTCATGGAAGGAGTCGACATCTCCCGCCG
GATCAGATCGGGTGCCCCAC

Downstream 100 bases:

>100_bases
GCTTTGGTCAGCTTGGGAGTGTCGGATCCATCCATGGAGCAGGAGCAAGCTGTCGTCGTCCGCCCCTCGCGGGAAGCGGA
CGTGGATGCCATGCTGGCGA

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MDYFKRFNFLFATPVFDAEDLEGARYNQIVAEIERSGFEVVKARNLEDAEIAVQTDAAIGCMLVDWGKKGLEGKTAALIN
LMRRRGLDFPILLLIRRKRFEDVPVEVLDFIDGYVFLSEETPAFIAKNLISRLKQYAETLKTPFFGALVDYAEEGNQLWT
CPGHNGGVFYSRSPIGRVFMEHLGEAVFRDDLDNSVLDLGDLLTHEGPALAAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
SALVTDGDLVLFDRNNHKAAHHGALMISGGIPVYVPTVRNAHGLIGPMDFAALDETALRERIRTHPLVKDPDAWQKPRPF
RVAVVEQCTYDGTIHNAEMILKAIGHLTDYILFDEAWAGFMKFHPLYAGRFAMGLADLGPDAPGIIATQSTHKQLASFSQ
ASQIHMKDRHITGQKRRVEHRRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRAVRREF
EEKELRPERRWFFEPFVPDRVAIPDVSSPGAVHEVPWESVATDLLATNPAFWHLTPGASWHGFEGMAAGFAMTDPNKLTL
LTPGFDRATGAYAEHGIPAPVVAQYLRENRIVAEKNDLNSLLFLLTPGVEASKAGTLISGLVAFKKLHDENALLEEAIPE
FFRRRPARYGGVRLRDLCGEMHRFFRAANVSALQAMQFSAAHLPDIALSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
VYPPGIATIVPGERLTERAKPMIDYLKMFEASFNTFPGFDVEIQGLYRETDASGRVRLHTYVVAE

Sequences:

>Translated_785_residues
MDYFKRFNFLFATPVFDAEDLEGARYNQIVAEIERSGFEVVKARNLEDAEIAVQTDAAIGCMLVDWGKKGLEGKTAALIN
LMRRRGLDFPILLLIRRKRFEDVPVEVLDFIDGYVFLSEETPAFIAKNLISRLKQYAETLKTPFFGALVDYAEEGNQLWT
CPGHNGGVFYSRSPIGRVFMEHLGEAVFRDDLDNSVLDLGDLLTHEGPALAAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
SALVTDGDLVLFDRNNHKAAHHGALMISGGIPVYVPTVRNAHGLIGPMDFAALDETALRERIRTHPLVKDPDAWQKPRPF
RVAVVEQCTYDGTIHNAEMILKAIGHLTDYILFDEAWAGFMKFHPLYAGRFAMGLADLGPDAPGIIATQSTHKQLASFSQ
ASQIHMKDRHITGQKRRVEHRRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRAVRREF
EEKELRPERRWFFEPFVPDRVAIPDVSSPGAVHEVPWESVATDLLATNPAFWHLTPGASWHGFEGMAAGFAMTDPNKLTL
LTPGFDRATGAYAEHGIPAPVVAQYLRENRIVAEKNDLNSLLFLLTPGVEASKAGTLISGLVAFKKLHDENALLEEAIPE
FFRRRPARYGGVRLRDLCGEMHRFFRAANVSALQAMQFSAAHLPDIALSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
VYPPGIATIVPGERLTERAKPMIDYLKMFEASFNTFPGFDVEIQGLYRETDASGRVRLHTYVVAE
>Mature_785_residues
MDYFKRFNFLFATPVFDAEDLEGARYNQIVAEIERSGFEVVKARNLEDAEIAVQTDAAIGCMLVDWGKKGLEGKTAALIN
LMRRRGLDFPILLLIRRKRFEDVPVEVLDFIDGYVFLSEETPAFIAKNLISRLKQYAETLKTPFFGALVDYAEEGNQLWT
CPGHNGGVFYSRSPIGRVFMEHLGEAVFRDDLDNSVLDLGDLLTHEGPALAAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
SALVTDGDLVLFDRNNHKAAHHGALMISGGIPVYVPTVRNAHGLIGPMDFAALDETALRERIRTHPLVKDPDAWQKPRPF
RVAVVEQCTYDGTIHNAEMILKAIGHLTDYILFDEAWAGFMKFHPLYAGRFAMGLADLGPDAPGIIATQSTHKQLASFSQ
ASQIHMKDRHITGQKRRVEHRRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRAVRREF
EEKELRPERRWFFEPFVPDRVAIPDVSSPGAVHEVPWESVATDLLATNPAFWHLTPGASWHGFEGMAAGFAMTDPNKLTL
LTPGFDRATGAYAEHGIPAPVVAQYLRENRIVAEKNDLNSLLFLLTPGVEASKAGTLISGLVAFKKLHDENALLEEAIPE
FFRRRPARYGGVRLRDLCGEMHRFFRAANVSALQAMQFSAAHLPDIALSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
VYPPGIATIVPGERLTERAKPMIDYLKMFEASFNTFPGFDVEIQGLYRETDASGRVRLHTYVVAE

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=713, Percent_Identity=43.4782608695652, Blast_Score=581, Evalue=1e-167,
Organism=Escherichia coli, GI87082193, Length=708, Percent_Identity=43.7853107344633, Blast_Score=575, Evalue=1e-165,
Organism=Escherichia coli, GI221142684, Length=746, Percent_Identity=32.4396782841823, Blast_Score=431, Evalue=1e-121,
Organism=Escherichia coli, GI1790573, Length=746, Percent_Identity=30.4289544235925, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1786384, Length=745, Percent_Identity=30.8724832214765, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 87663; Mature: 87663

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFKRFNFLFATPVFDAEDLEGARYNQIVAEIERSGFEVVKARNLEDAEIAVQTDAAIG
CCHHHHCCEEEECCCCCHHHCCCCHHHHHHHHHHHCCHHEEHHCCCCCCEEEEEECCCEE
CMLVDWGKKGLEGKTAALINLMRRRGLDFPILLLIRRKRFEDVPVEVLDFIDGYVFLSEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCEEEECCC
TPAFIAKNLISRLKQYAETLKTPFFGALVDYAEEGNQLWTCPGHNGGVFYSRSPIGRVFM
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCEEEECCCHHHHHH
EHLGEAVFRDDLDNSVLDLGDLLTHEGPALAAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEE
SALVTDGDLVLFDRNNHKAAHHGALMISGGIPVYVPTVRNAHGLIGPMDFAALDETALRE
EEEEECCCEEEEECCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHH
RIRTHPLVKDPDAWQKPRPFRVAVVEQCTYDGTIHNAEMILKAIGHLTDYILFDEAWAGF
HHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKFHPLYAGRFAMGLADLGPDAPGIIATQSTHKQLASFSQASQIHMKDRHITGQKRRVEH
HHHCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHEECCCCCCCHHHHHHH
RRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRAVRREF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
EEKELRPERRWFFEPFVPDRVAIPDVSSPGAVHEVPWESVATDLLATNPAFWHLTPGASW
HHHHCCCHHHEECCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCC
HGFEGMAAGFAMTDPNKLTLLTPGFDRATGAYAEHGIPAPVVAQYLRENRIVAEKNDLNS
CCCCCHHCCEEECCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHCCCEEECCCCCC
LLFLLTPGVEASKAGTLISGLVAFKKLHDENALLEEAIPEFFRRRPARYGGVRLRDLCGE
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MHRFFRAANVSALQAMQFSAAHLPDIALSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCEECCCEE
VYPPGIATIVPGERLTERAKPMIDYLKMFEASFNTFPGFDVEIQGLYRETDASGRVRLHT
EECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCEEEEEE
YVVAE
EEEEC
>Mature Secondary Structure
MDYFKRFNFLFATPVFDAEDLEGARYNQIVAEIERSGFEVVKARNLEDAEIAVQTDAAIG
CCHHHHCCEEEECCCCCHHHCCCCHHHHHHHHHHHCCHHEEHHCCCCCCEEEEEECCCEE
CMLVDWGKKGLEGKTAALINLMRRRGLDFPILLLIRRKRFEDVPVEVLDFIDGYVFLSEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCEEEECCC
TPAFIAKNLISRLKQYAETLKTPFFGALVDYAEEGNQLWTCPGHNGGVFYSRSPIGRVFM
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCEEEECCCHHHHHH
EHLGEAVFRDDLDNSVLDLGDLLTHEGPALAAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEE
SALVTDGDLVLFDRNNHKAAHHGALMISGGIPVYVPTVRNAHGLIGPMDFAALDETALRE
EEEEECCCEEEEECCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHH
RIRTHPLVKDPDAWQKPRPFRVAVVEQCTYDGTIHNAEMILKAIGHLTDYILFDEAWAGF
HHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKFHPLYAGRFAMGLADLGPDAPGIIATQSTHKQLASFSQASQIHMKDRHITGQKRRVEH
HHHCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHEECCCCCCCHHHHHHH
RRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRAVRREF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
EEKELRPERRWFFEPFVPDRVAIPDVSSPGAVHEVPWESVATDLLATNPAFWHLTPGASW
HHHHCCCHHHEECCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCC
HGFEGMAAGFAMTDPNKLTLLTPGFDRATGAYAEHGIPAPVVAQYLRENRIVAEKNDLNS
CCCCCHHCCEEECCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHCCCEEECCCCCC
LLFLLTPGVEASKAGTLISGLVAFKKLHDENALLEEAIPEFFRRRPARYGGVRLRDLCGE
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MHRFFRAANVSALQAMQFSAAHLPDIALSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCEECCCEE
VYPPGIATIVPGERLTERAKPMIDYLKMFEASFNTFPGFDVEIQGLYRETDASGRVRLHT
EECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCEEEEEE
YVVAE
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]