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The map label for this gene is ompR [H]

Identifier: 154244586

GI number: 154244586

Start: 713896

End: 714663

Strand: Reverse

Name: ompR [H]

Synonym: Xaut_0634

Alternate gene names: 154244586

Gene position: 714663-713896 (Counterclockwise)

Preceding gene: 154244587

Following gene: 154244583

Centisome position: 13.46

GC content: 70.44

Gene sequence:

>768_bases
ATGGTGGGGCAATCGAAGGGCGGGGAGACGGGCTGGCGCATCATCGTGGTGGACGACGAGGAAGCGCTGCGCGAGACCGT
GGCCGAATATCTCGCCGGCCAGGGATTTCGCGTGCGCTCGGCCGCGAGCGGGCGCGATCTCGACACTCTGCTGGCCGCCG
AGCCGGCTGACCTCATCCTCATGGACGTGCACATGCCGGGAGAGGATGGCCTCACCCTCGCCCGCCGCATCCGCTCCGCC
GCCGCGACGCCCATCATCATGCTGACCGCGGCCGACGACATCGTGGACCGCGTGGCGGGCCTTGAGGTCGGCGCCGACGA
TTATGTGGTGAAGCCCTTCGACCTGCGCGAGCTGAAGGCGCGCATCCGCGCCGTGCTGCGCCGCTACACCGCGGTCCCGC
CGCCCACGCACGAGCCACCTCCGGCGAACGGCGCCGTGCCCGCCGGTGCGGACCTGGTGCCGTGCGGCGTCGTCTTCCTG
GACATGGAGGCCCACTGCCTCGTCAGGCGCGACGGCACGCGGGAGATGCTCACCGCCATGGAGTTCGACCTGCTGCGTGT
GTTCCTGCAGAACCCCAACCGCGTCCTCACCCGCGACCGGCTGCTCGACCTTGCCCACGACCGGGACAACGAGCCGTTCG
ACCGCAGCATCGACGTGCGGGTGACGCGCCTGCGCAAGAAGATCGAAGCCGATCCGGCCAAGCCCCAGGCCATCAAGACG
GTGCGGGGCGTCGGCTACCTGTTCGTGCCCGGTCCCCGGGGCACATGA

Upstream 100 bases:

>100_bases
CTGCCCAACCTGCGCCTTGGCCATTCCGTTCAGGCAGCGTCCGCCCTAGAGTGCGCGCCCTGCGGGTATCTGGTGAGGGG
AGCGCTTCCGGCGCGCGAGC

Downstream 100 bases:

>100_bases
CGACACCTCCGGCCGGGGTCTCCGTGAACGGGAGGCTCCGGCCGGAGGATCGCACACGGAACGGCAGCGCGGGGATGCCG
CCGTCCGCGTTTCAGAGCGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MVGQSKGGETGWRIIVVDDEEALRETVAEYLAGQGFRVRSAASGRDLDTLLAAEPADLILMDVHMPGEDGLTLARRIRSA
AATPIIMLTAADDIVDRVAGLEVGADDYVVKPFDLRELKARIRAVLRRYTAVPPPTHEPPPANGAVPAGADLVPCGVVFL
DMEAHCLVRRDGTREMLTAMEFDLLRVFLQNPNRVLTRDRLLDLAHDRDNEPFDRSIDVRVTRLRKKIEADPAKPQAIKT
VRGVGYLFVPGPRGT

Sequences:

>Translated_255_residues
MVGQSKGGETGWRIIVVDDEEALRETVAEYLAGQGFRVRSAASGRDLDTLLAAEPADLILMDVHMPGEDGLTLARRIRSA
AATPIIMLTAADDIVDRVAGLEVGADDYVVKPFDLRELKARIRAVLRRYTAVPPPTHEPPPANGAVPAGADLVPCGVVFL
DMEAHCLVRRDGTREMLTAMEFDLLRVFLQNPNRVLTRDRLLDLAHDRDNEPFDRSIDVRVTRLRKKIEADPAKPQAIKT
VRGVGYLFVPGPRGT
>Mature_255_residues
MVGQSKGGETGWRIIVVDDEEALRETVAEYLAGQGFRVRSAASGRDLDTLLAAEPADLILMDVHMPGEDGLTLARRIRSA
AATPIIMLTAADDIVDRVAGLEVGADDYVVKPFDLRELKARIRAVLRRYTAVPPPTHEPPPANGAVPAGADLVPCGVVFL
DMEAHCLVRRDGTREMLTAMEFDLLRVFLQNPNRVLTRDRLLDLAHDRDNEPFDRSIDVRVTRLRKKIEADPAKPQAIKT
VRGVGYLFVPGPRGT

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=251, Percent_Identity=43.4262948207171, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=33.7552742616034, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=34.8739495798319, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=239, Percent_Identity=36.4016736401674, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786911, Length=237, Percent_Identity=35.4430379746835, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786784, Length=237, Percent_Identity=38.3966244725738, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786599, Length=239, Percent_Identity=35.1464435146443, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082012, Length=237, Percent_Identity=32.0675105485232, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=238, Percent_Identity=33.1932773109244, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=237, Percent_Identity=32.9113924050633, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790860, Length=239, Percent_Identity=33.0543933054393, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI2367329, Length=240, Percent_Identity=36.25, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789402, Length=235, Percent_Identity=30.2127659574468, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=30.5785123966942, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=39.6551724137931, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790437, Length=172, Percent_Identity=30.2325581395349, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=119, Percent_Identity=31.0924369747899, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=107, Percent_Identity=35.5140186915888, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28022; Mature: 28022

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGQSKGGETGWRIIVVDDEEALRETVAEYLAGQGFRVRSAASGRDLDTLLAAEPADLIL
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCEEE
MDVHMPGEDGLTLARRIRSAAATPIIMLTAADDIVDRVAGLEVGADDYVVKPFDLRELKA
EEEECCCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCEECCCCHHHHHH
RIRAVLRRYTAVPPPTHEPPPANGAVPAGADLVPCGVVFLDMEAHCLVRRDGTREMLTAM
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHH
EFDLLRVFLQNPNRVLTRDRLLDLAHDRDNEPFDRSIDVRVTRLRKKIEADPAKPQAIKT
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
VRGVGYLFVPGPRGT
HHCCEEEEECCCCCC
>Mature Secondary Structure
MVGQSKGGETGWRIIVVDDEEALRETVAEYLAGQGFRVRSAASGRDLDTLLAAEPADLIL
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCEEE
MDVHMPGEDGLTLARRIRSAAATPIIMLTAADDIVDRVAGLEVGADDYVVKPFDLRELKA
EEEECCCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCEECCCCHHHHHH
RIRAVLRRYTAVPPPTHEPPPANGAVPAGADLVPCGVVFLDMEAHCLVRRDGTREMLTAM
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHH
EFDLLRVFLQNPNRVLTRDRLLDLAHDRDNEPFDRSIDVRVTRLRKKIEADPAKPQAIKT
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
VRGVGYLFVPGPRGT
HHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]