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The map label for this gene is 154244437

Identifier: 154244437

GI number: 154244437

Start: 531517

End: 532557

Strand: Reverse

Name: 154244437

Synonym: Xaut_0480

Alternate gene names: NA

Gene position: 532557-531517 (Counterclockwise)

Preceding gene: 154244450

Following gene: 154244436

Centisome position: 10.03

GC content: 69.07

Gene sequence:

>1041_bases
ATGAAGGTGTGCATCTACGGAGCCGGAGCCATCGGCGGATATCTGGGCGCCCAGCTCGCCAGCGCCGGCGCCGAGGTGAG
CCTGGTGGCCCGCGGCGGCCATCTGGAAGCCATGCAGACCAACGGCCTGAAGCTGCTGATCAACGGCGAGGAGCGCGTGA
GCCATGTCCGCGCCACCGACGATCCCCGCGAGCTCGGCCCGCAGGATTACGTCATCATCGCCCTCAAGGGACATTCGGTG
CCGGGCGTGGTGGACCGGCTGCGCCCCCTCATGGGCAACGACACCGCCATCGTCACCGCCGTGAACGGTGTGCCCTACTG
GTATTTCTACAAGCATGGCGGCGCCCTCGAGAACCGGACCCTGTCCACCATCGATCCCGGCGCCCGCCAGTGGGAGGTGC
TGGGGCCTGAGCGCGCGCTCGGCTGCATCGTCTATCCGGCCACCGAGGTGGTGGCGCCGGGCGTGATCCAGCACATCTAC
GGCGACAAGTTCCCCCTCGGCGAGCCCTCGGGCGAGATCACGCCGCGGGTCACAGCCCTCAGCCAGATGATGGAGAAGGG
CGGCCTGCGCGCGCCGGTTTTGACCAACATCCGCGACGAGCTGTGGCTGAAGCTGTGGGGCAATCTCTGCTTCAACCCCA
TCAGCGCCCTCACCCACGCCACCCTCGACATCATCGCCGCCGATCCCGGCACCCGCGCCGTGGCCCGCTCCATGATGCTG
GAGGCCAAGGCCGTCGCCGAGAAGCTGGGCATCAACTTCCGGGTGGATGTGGAGCGGCGCATCAACGGCGCCGGCGCGGT
GGGCGCCCACAAGACCTCCATGCTGCAGGACCTCGAGCGCGATCGCCCCATGGAGATCGACCCGCTGGTGAGCGTGGTCC
AGGAAATGGCGCAGATGCTCGAACTGCCCACCCCCACCCTCGACGTGGTGCTGGCTCTGGTGCGCCAGCGCGCGGCCATG
GCCGGCCTCGGCGACATCCTCGCCGTGCCGCCGGTCACCGCCGCCGATCTCGTGCCCGCCAAGAAGGCTGCCGCGCACTG
A

Upstream 100 bases:

>100_bases
AATTTCCACTGCTATCGTGGGGACCATGGTTGCCAAGGGCGGAGCGTGCGCTCTAATCTGGCATACATAATACGCAATGA
ACGATCGGGAGGGATCTGCC

Downstream 100 bases:

>100_bases
GCCGGGCGAGGCTCCGGCCGGCGGCAACGCCCCGAAGCCCCTGCCCCAAGGTCATGACACACGCAAAAGAAAAGGCCGGG
TCTCGCCCGGCCTTTTTCGT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKVCIYGAGAIGGYLGAQLASAGAEVSLVARGGHLEAMQTNGLKLLINGEERVSHVRATDDPRELGPQDYVIIALKGHSV
PGVVDRLRPLMGNDTAIVTAVNGVPYWYFYKHGGALENRTLSTIDPGARQWEVLGPERALGCIVYPATEVVAPGVIQHIY
GDKFPLGEPSGEITPRVTALSQMMEKGGLRAPVLTNIRDELWLKLWGNLCFNPISALTHATLDIIAADPGTRAVARSMML
EAKAVAEKLGINFRVDVERRINGAGAVGAHKTSMLQDLERDRPMEIDPLVSVVQEMAQMLELPTPTLDVVLALVRQRAAM
AGLGDILAVPPVTAADLVPAKKAAAH

Sequences:

>Translated_346_residues
MKVCIYGAGAIGGYLGAQLASAGAEVSLVARGGHLEAMQTNGLKLLINGEERVSHVRATDDPRELGPQDYVIIALKGHSV
PGVVDRLRPLMGNDTAIVTAVNGVPYWYFYKHGGALENRTLSTIDPGARQWEVLGPERALGCIVYPATEVVAPGVIQHIY
GDKFPLGEPSGEITPRVTALSQMMEKGGLRAPVLTNIRDELWLKLWGNLCFNPISALTHATLDIIAADPGTRAVARSMML
EAKAVAEKLGINFRVDVERRINGAGAVGAHKTSMLQDLERDRPMEIDPLVSVVQEMAQMLELPTPTLDVVLALVRQRAAM
AGLGDILAVPPVTAADLVPAKKAAAH
>Mature_346_residues
MKVCIYGAGAIGGYLGAQLASAGAEVSLVARGGHLEAMQTNGLKLLINGEERVSHVRATDDPRELGPQDYVIIALKGHSV
PGVVDRLRPLMGNDTAIVTAVNGVPYWYFYKHGGALENRTLSTIDPGARQWEVLGPERALGCIVYPATEVVAPGVIQHIY
GDKFPLGEPSGEITPRVTALSQMMEKGGLRAPVLTNIRDELWLKLWGNLCFNPISALTHATLDIIAADPGTRAVARSMML
EAKAVAEKLGINFRVDVERRINGAGAVGAHKTSMLQDLERDRPMEIDPLVSVVQEMAQMLELPTPTLDVVLALVRQRAAM
AGLGDILAVPPVTAADLVPAKKAAAH

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 36948; Mature: 36948

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVCIYGAGAIGGYLGAQLASAGAEVSLVARGGHLEAMQTNGLKLLINGEERVSHVRATD
CEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCEEEEECCHHHHHHCCCCC
DPRELGPQDYVIIALKGHSVPGVVDRLRPLMGNDTAIVTAVNGVPYWYFYKHGGALENRT
CHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCE
LSTIDPGARQWEVLGPERALGCIVYPATEVVAPGVIQHIYGDKFPLGEPSGEITPRVTAL
ECCCCCCCCEEEEECCCHHCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
SQMMEKGGLRAPVLTNIRDELWLKLWGNLCFNPISALTHATLDIIAADPGTRAVARSMML
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCCHHHHHHHHHH
EAKAVAEKLGINFRVDVERRINGAGAVGAHKTSMLQDLERDRPMEIDPLVSVVQEMAQML
HHHHHHHHHCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ELPTPTLDVVLALVRQRAAMAGLGDILAVPPVTAADLVPAKKAAAH
HCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHCCCCHHHCCC
>Mature Secondary Structure
MKVCIYGAGAIGGYLGAQLASAGAEVSLVARGGHLEAMQTNGLKLLINGEERVSHVRATD
CEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCEEEEECCHHHHHHCCCCC
DPRELGPQDYVIIALKGHSVPGVVDRLRPLMGNDTAIVTAVNGVPYWYFYKHGGALENRT
CHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCE
LSTIDPGARQWEVLGPERALGCIVYPATEVVAPGVIQHIYGDKFPLGEPSGEITPRVTAL
ECCCCCCCCEEEEECCCHHCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
SQMMEKGGLRAPVLTNIRDELWLKLWGNLCFNPISALTHATLDIIAADPGTRAVARSMML
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCCHHHHHHHHHH
EAKAVAEKLGINFRVDVERRINGAGAVGAHKTSMLQDLERDRPMEIDPLVSVVQEMAQML
HHHHHHHHHCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ELPTPTLDVVLALVRQRAAMAGLGDILAVPPVTAADLVPAKKAAAH
HCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]