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The map label for this gene is lgrC [H]

Identifier: 154244382

GI number: 154244382

Start: 457377

End: 461594

Strand: Reverse

Name: lgrC [H]

Synonym: Xaut_0425

Alternate gene names: 154244382

Gene position: 461594-457377 (Counterclockwise)

Preceding gene: 154244383

Following gene: 154244381

Centisome position: 8.69

GC content: 68.33

Gene sequence:

>4218_bases
ATGAACGTCGTCACGGCCCCGATCCCGCTTGCCGTCGTCACCCAGCGCATCTGGCTGGAATGCAAGCGGGCCCCGGACAG
CTCGGCCTATTTCGTGCCGTTCGTCTATCGCCTGAACCCCGATATCGACCCCGACCGCCTGGAACAGGCCCTGCGCGAGA
CCATCGCCGCGCATCCCGCCCTGCGCTCGGTGATCCGGGAGGTGGAGGGCAAGCCCTACCAGGTGGTTCTGGATACACCG
GCGCGGGTGCTGGAGCGCTCCGATAGCTGGGAGTGGGCTATCACCAAGCCGTTCGACGTGGAGAACGGCCCCCTGTTCCG
GTTCGTGCTGTGCGGCGACATCTTCGTCCTCAACGGCAGCCACATGGTGCTCGACGGCGGCTCCATCATGCTGCTGATGG
AGGAGGTCGGCGCCCGCTATCACGGCGAGGCGGTGCCCGAGCCCGGCCCTGGCCCGGCAGCGTGGGACGCCCACGAGCGC
GCCTATCTGGACAGCCCCGACCACGAGGCCGACCGGGCCTATTGGATCGAGGCGCTGGCCCAGTCCGATTTCCACGCCGG
CCTGCCGACGCGGCGGGAGAGCTACCAGGGCGAGAAGGACGGCAATCTCTATTTCTCCCTGCGCCTGCCGCAGATGAATG
TCAGCCCGTTCATCACCACGCTGGCGCTGGTCCAGGCCCTGATCCACCGCTACACCGAGCAGGAGATGGTGGCGGTGCTC
TACCCCACGGACCTGCGCGGCAAGCCGTTCGCCCGCTCCATGGGCTCCTTCGTCAACACGCTGATCGCCACCGCGAGCTT
CACGCCGGAGCTGACCTTCGCCCAGTTGGTGCAGCAGGTGCAGGAACAGCGCCGCGCCACCCGCGAGCACGACCGCCTGT
CGTTCCAGGAGGTGATCGCCGGCCTGCGCAAGGCGCGCCCGTCCGATGGCATCCAATTGCCCAACGTCTCCGTATCCTGG
GCCAAGCCCCTGTGGCCGTTCACGCTAGGCACGCCGCTGCCGCTCGAGACGGTGGATTGCCAGAACGACCTCCTGTTCCT
CGCCTTCGCCGAGGGCGAGCGGCTGGACGTGCGGCTGCAATACCAGGCGGCCCAGTTCACCCGCCGCTTCGCCGAGGAGC
TAGCGGCCCACCTCTCCCTGCTCGCCGATGCGGTGAGCGCCCAGCCTGATGCGCCACTGTCGAAGCTGAGGCTCGCCACC
GAGGCGGAGGTGCAGCGGATCGAGACCGAGCGGACGCCGCAGCCCGCGCCCCGTCCCGACCTGCAACTGATCCACGACGC
CTTCTCCGACTGGGCCGAGCGCCAGCCGGACGCCCCTGCCCTGCTCATGCGTGAGCGGGTGGTGACCTATGGCGAGATGG
AGCGCCTGACCAACCGCATCGCCCACGGCCTGCGCCGGCGGGGCGTGAAGCCCAACACGCTGGTCGCGGTGATGATGGAG
AAGGGATGGGAGCAGGCGGTGGCCTGCATGGCCATCCTCAAGGCGGGTGCCGGCTACCTGCCCATCAATGCCGCCTGGCC
GCCCGAGCGCATGGATGCCGTGAACGCGCAAGGCGAGGTGGAGATCGTGCTGAGCCAGCAGCGCGTGCTCGACCGCCTCG
GCCGCCCCGGCCTCGCGGTGGACGACGACGCCCTGTGGGCGGACGAGCCGGACACCCGCCTGCCCTCCGTCAACGACATC
GGCGACATCTGCTACGTGCTGTTCACCTCTGGCTCCACCGGCAAGCCCAAGGGCGTGACGCTGACCCATTTCAGCGTCAT
GAACACCCTGCGCAACGCCAATGCGGAGCATGGCGTCGGGCCGGGCGACCGGTCGCTGCAGCTGTCGGATTTCAGCTTCG
ACCTCTCGGTCTACGACATCTTCGGCATGCTCTCCGCCGGTGCCGGCGTGGTGATCCCGGACGAGGACCGGCACCTGGAG
CCGCCGCACTGGGTGGAACTGGTACGCCAGCATCAGGCCACCATCTGGCTCAGCGTGCCCATGTATGTGGACATGTGGGT
GCAGTCGGGCGAGGCGCTGCCCACCATCCGCGTGTTCATGATGGGCGGCGACAAGATCCCCACCGACCTGCCGGACCGCA
TGCGCCCGCTCGCCCCAGACGCTGTGATCTGGAGCGTGGGCGGCCCCACCGAAACCTCCATCATCTCCAACTGGTACCGC
ATCGGCGCGGTGGACCCGATCTGGACCACCATCCCCTATGGCCGGGCCATGCCGAACCAGAAGATGCTGGTGCTTGACCC
CGGTCTCAACCACTGCCCGCCCTTCATGCCGGGGCGGATCTTCATGGGCGGCGTTTGCCTCGCGCGGGGCTACTGGCACG
ACGAAGAGAAGACCGCCGCCGCCTTCATCACCTATCCCGCCACTGGCGAGCGCATCTATTACACCGGCGACCTCGGCCGC
TGGCTCCCGGACGGGCAGGTGGAATTTCTCGGCCGGGCCGACTTCCAGGTGAAGGTGAACGGCTTCCGGGTGGAGCTGGG
CGAGATCGAGGGCGCCATCGAGGCGCTGCCGGGCGTGAAGGCCGCCATCGTGGACGGGCAGGACCAGCCCAACCGTAAGG
GCAAGTTCCTGGTGGCCTATGTGGTCTCGGAAGACGCGCTGGACGCCGCCGAGATGCGTGCCGCCCTGCAGGACAAGCTG
CCCTATTACATGATCCCGCGGGTGTTCGTGCCGCTGGAGCGCATCCCGCTCTCGGCCAATGGCAAGGTGGACCGCAAGGC
CCTGCCCCGTCCCGACGTGGCGCAGATGCCCGGCGAACTGCCCTACGTGCCGCCGCGCACCGAGACCGAGGCGGCGCTGG
TGGACATCTGGCAGGCCGTGCTGAAGCACGAGCCCATCGGCATCCACGACAATTTCTATGCGCTCGGCGGCGATTCGCTG
CTGGCGGTGCAGCTCGGCATCAAGGCGCGGGAGGTGGGGCTGCCGCTCGATCCCACCGCGCTCCAGCGCACCCCCACCAT
CGCCGAGCTGGTGCAGGGCCTTGCCCCGGTGAAGGCAGTGGATGCAAGCGAGGCGACAGGCGACGAGCCGCTGTCTCCCA
TGCAGCGCTACTACTTCACCTGGGCGACGGAACGGCCCCAGCAGTTCAACGTCTCCGCCGTGTTCCGCTGCGCGCTGGAG
CCGGAGCGGCTGCGCGACGCCCTCAAGACGCTGGTGGCGCACCACGACGCCCTGCGCCTCCGCTTCCATGACGGACGGCA
GTATTATGTGGAGACCGGCATCGAGGTGCCGCTGGAGTGCGCCGACATCCCGCTGGCGGATGTGGCCGCGCGGGCGGCGC
AGATGCAGGAGACCATCGACATCGCGCAGGGCCCCATCATGCGGGCCGGCCTGTTCACCACGGAAGACGGCCAGCGCCTG
GTGCTGATCTGCCATCATCTGGTGACCGACGGCCTCTCCTGGGGCGCGGTGGTCACCGACCTGCAGCGGGCCTATCTGGG
CCAGCCGCTGGCTCCGGCAGGCGGCACCTACAAGGCTTGGGTGGAAGGCCTCATCAGCTACGCCGCTACCCCGGAAGCCG
AGGCGCAATTCCCCTACTGGTTGGAACAGCAGGGCCCCACCTTCACCCCCGACAGCGACCAGCCCGGTGCCCGGCAGCGG
GACATCGTGACCTTCCAGAGCGTCATGCTCGACGAGACCCCGCACAATCCTTATGAGCGCGTCGCCGCCGCCCTGGTGGA
GGCCTCGGGCCAGGACAGGCTGATGCTGCACGTGGTGGGCCACGGGCGCGAGCCGGTGGTGGAGGGGGTGGACCCCACCC
GCATCTGCGGCTGGTTCACCACCCATACGCCCATCGTGCTGTCGGGCGGCCTTGCGGACGTAGCCGGGCAGCTTCACGCC
ATGCCCCGGCACGGCATCGCCCATGGCGCGCTGCGCGCCTATCATCCGCGCGGGGCGGAGCTGGCGGTGCAGGACCAAGT
GAAGATCCTGTACAATTTCTTCGGCGAGACCTGGGACGCGAGCTTCCACGGCGCGGTGTTCGAGAAGCCGGAAGAGGACC
TGCTCTACCTCAAGAACCACGCGTTCGCCGATAACCCGGCGGACTTCTGGCTGTATCTGGTGGCCGTCATCCATGAGGGC
AAGCTTCAGGTGCGGTTCCAGTACTCGTCCGTCAACTACAAGGAAGAAACCATCCGCGGCCTGGCCGACCGGATGCGGGA
GAGCCTGAAGGCGCACCTAAACGACCCCGTCGCAGCTCCGGTCGCCGCGCCGGCATGA

Upstream 100 bases:

>100_bases
AGGCCGGTTTCCTGCATCAATCCGGCCGCTCGCCTCGTCCCAACCCGCATCCGTCCCCCTCCGCACGGCAACCCCGCGCG
CCAGCATCGGGAAGACCTCG

Downstream 100 bases:

>100_bases
TCGCGCTCTATCTGCTGATCCTGGTGGATTCCATCAGCGCGACCGTCATCATCCCGCTGCTCGGTCCGCTGCTGATCGAC
CCGGCGACGCTGGTGTTCCT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1405; Mature: 1405

Protein sequence:

>1405_residues
MNVVTAPIPLAVVTQRIWLECKRAPDSSAYFVPFVYRLNPDIDPDRLEQALRETIAAHPALRSVIREVEGKPYQVVLDTP
ARVLERSDSWEWAITKPFDVENGPLFRFVLCGDIFVLNGSHMVLDGGSIMLLMEEVGARYHGEAVPEPGPGPAAWDAHER
AYLDSPDHEADRAYWIEALAQSDFHAGLPTRRESYQGEKDGNLYFSLRLPQMNVSPFITTLALVQALIHRYTEQEMVAVL
YPTDLRGKPFARSMGSFVNTLIATASFTPELTFAQLVQQVQEQRRATREHDRLSFQEVIAGLRKARPSDGIQLPNVSVSW
AKPLWPFTLGTPLPLETVDCQNDLLFLAFAEGERLDVRLQYQAAQFTRRFAEELAAHLSLLADAVSAQPDAPLSKLRLAT
EAEVQRIETERTPQPAPRPDLQLIHDAFSDWAERQPDAPALLMRERVVTYGEMERLTNRIAHGLRRRGVKPNTLVAVMME
KGWEQAVACMAILKAGAGYLPINAAWPPERMDAVNAQGEVEIVLSQQRVLDRLGRPGLAVDDDALWADEPDTRLPSVNDI
GDICYVLFTSGSTGKPKGVTLTHFSVMNTLRNANAEHGVGPGDRSLQLSDFSFDLSVYDIFGMLSAGAGVVIPDEDRHLE
PPHWVELVRQHQATIWLSVPMYVDMWVQSGEALPTIRVFMMGGDKIPTDLPDRMRPLAPDAVIWSVGGPTETSIISNWYR
IGAVDPIWTTIPYGRAMPNQKMLVLDPGLNHCPPFMPGRIFMGGVCLARGYWHDEEKTAAAFITYPATGERIYYTGDLGR
WLPDGQVEFLGRADFQVKVNGFRVELGEIEGAIEALPGVKAAIVDGQDQPNRKGKFLVAYVVSEDALDAAEMRAALQDKL
PYYMIPRVFVPLERIPLSANGKVDRKALPRPDVAQMPGELPYVPPRTETEAALVDIWQAVLKHEPIGIHDNFYALGGDSL
LAVQLGIKAREVGLPLDPTALQRTPTIAELVQGLAPVKAVDASEATGDEPLSPMQRYYFTWATERPQQFNVSAVFRCALE
PERLRDALKTLVAHHDALRLRFHDGRQYYVETGIEVPLECADIPLADVAARAAQMQETIDIAQGPIMRAGLFTTEDGQRL
VLICHHLVTDGLSWGAVVTDLQRAYLGQPLAPAGGTYKAWVEGLISYAATPEAEAQFPYWLEQQGPTFTPDSDQPGARQR
DIVTFQSVMLDETPHNPYERVAAALVEASGQDRLMLHVVGHGREPVVEGVDPTRICGWFTTHTPIVLSGGLADVAGQLHA
MPRHGIAHGALRAYHPRGAELAVQDQVKILYNFFGETWDASFHGAVFEKPEEDLLYLKNHAFADNPADFWLYLVAVIHEG
KLQVRFQYSSVNYKEETIRGLADRMRESLKAHLNDPVAAPVAAPA

Sequences:

>Translated_1405_residues
MNVVTAPIPLAVVTQRIWLECKRAPDSSAYFVPFVYRLNPDIDPDRLEQALRETIAAHPALRSVIREVEGKPYQVVLDTP
ARVLERSDSWEWAITKPFDVENGPLFRFVLCGDIFVLNGSHMVLDGGSIMLLMEEVGARYHGEAVPEPGPGPAAWDAHER
AYLDSPDHEADRAYWIEALAQSDFHAGLPTRRESYQGEKDGNLYFSLRLPQMNVSPFITTLALVQALIHRYTEQEMVAVL
YPTDLRGKPFARSMGSFVNTLIATASFTPELTFAQLVQQVQEQRRATREHDRLSFQEVIAGLRKARPSDGIQLPNVSVSW
AKPLWPFTLGTPLPLETVDCQNDLLFLAFAEGERLDVRLQYQAAQFTRRFAEELAAHLSLLADAVSAQPDAPLSKLRLAT
EAEVQRIETERTPQPAPRPDLQLIHDAFSDWAERQPDAPALLMRERVVTYGEMERLTNRIAHGLRRRGVKPNTLVAVMME
KGWEQAVACMAILKAGAGYLPINAAWPPERMDAVNAQGEVEIVLSQQRVLDRLGRPGLAVDDDALWADEPDTRLPSVNDI
GDICYVLFTSGSTGKPKGVTLTHFSVMNTLRNANAEHGVGPGDRSLQLSDFSFDLSVYDIFGMLSAGAGVVIPDEDRHLE
PPHWVELVRQHQATIWLSVPMYVDMWVQSGEALPTIRVFMMGGDKIPTDLPDRMRPLAPDAVIWSVGGPTETSIISNWYR
IGAVDPIWTTIPYGRAMPNQKMLVLDPGLNHCPPFMPGRIFMGGVCLARGYWHDEEKTAAAFITYPATGERIYYTGDLGR
WLPDGQVEFLGRADFQVKVNGFRVELGEIEGAIEALPGVKAAIVDGQDQPNRKGKFLVAYVVSEDALDAAEMRAALQDKL
PYYMIPRVFVPLERIPLSANGKVDRKALPRPDVAQMPGELPYVPPRTETEAALVDIWQAVLKHEPIGIHDNFYALGGDSL
LAVQLGIKAREVGLPLDPTALQRTPTIAELVQGLAPVKAVDASEATGDEPLSPMQRYYFTWATERPQQFNVSAVFRCALE
PERLRDALKTLVAHHDALRLRFHDGRQYYVETGIEVPLECADIPLADVAARAAQMQETIDIAQGPIMRAGLFTTEDGQRL
VLICHHLVTDGLSWGAVVTDLQRAYLGQPLAPAGGTYKAWVEGLISYAATPEAEAQFPYWLEQQGPTFTPDSDQPGARQR
DIVTFQSVMLDETPHNPYERVAAALVEASGQDRLMLHVVGHGREPVVEGVDPTRICGWFTTHTPIVLSGGLADVAGQLHA
MPRHGIAHGALRAYHPRGAELAVQDQVKILYNFFGETWDASFHGAVFEKPEEDLLYLKNHAFADNPADFWLYLVAVIHEG
KLQVRFQYSSVNYKEETIRGLADRMRESLKAHLNDPVAAPVAAPA
>Mature_1405_residues
MNVVTAPIPLAVVTQRIWLECKRAPDSSAYFVPFVYRLNPDIDPDRLEQALRETIAAHPALRSVIREVEGKPYQVVLDTP
ARVLERSDSWEWAITKPFDVENGPLFRFVLCGDIFVLNGSHMVLDGGSIMLLMEEVGARYHGEAVPEPGPGPAAWDAHER
AYLDSPDHEADRAYWIEALAQSDFHAGLPTRRESYQGEKDGNLYFSLRLPQMNVSPFITTLALVQALIHRYTEQEMVAVL
YPTDLRGKPFARSMGSFVNTLIATASFTPELTFAQLVQQVQEQRRATREHDRLSFQEVIAGLRKARPSDGIQLPNVSVSW
AKPLWPFTLGTPLPLETVDCQNDLLFLAFAEGERLDVRLQYQAAQFTRRFAEELAAHLSLLADAVSAQPDAPLSKLRLAT
EAEVQRIETERTPQPAPRPDLQLIHDAFSDWAERQPDAPALLMRERVVTYGEMERLTNRIAHGLRRRGVKPNTLVAVMME
KGWEQAVACMAILKAGAGYLPINAAWPPERMDAVNAQGEVEIVLSQQRVLDRLGRPGLAVDDDALWADEPDTRLPSVNDI
GDICYVLFTSGSTGKPKGVTLTHFSVMNTLRNANAEHGVGPGDRSLQLSDFSFDLSVYDIFGMLSAGAGVVIPDEDRHLE
PPHWVELVRQHQATIWLSVPMYVDMWVQSGEALPTIRVFMMGGDKIPTDLPDRMRPLAPDAVIWSVGGPTETSIISNWYR
IGAVDPIWTTIPYGRAMPNQKMLVLDPGLNHCPPFMPGRIFMGGVCLARGYWHDEEKTAAAFITYPATGERIYYTGDLGR
WLPDGQVEFLGRADFQVKVNGFRVELGEIEGAIEALPGVKAAIVDGQDQPNRKGKFLVAYVVSEDALDAAEMRAALQDKL
PYYMIPRVFVPLERIPLSANGKVDRKALPRPDVAQMPGELPYVPPRTETEAALVDIWQAVLKHEPIGIHDNFYALGGDSL
LAVQLGIKAREVGLPLDPTALQRTPTIAELVQGLAPVKAVDASEATGDEPLSPMQRYYFTWATERPQQFNVSAVFRCALE
PERLRDALKTLVAHHDALRLRFHDGRQYYVETGIEVPLECADIPLADVAARAAQMQETIDIAQGPIMRAGLFTTEDGQRL
VLICHHLVTDGLSWGAVVTDLQRAYLGQPLAPAGGTYKAWVEGLISYAATPEAEAQFPYWLEQQGPTFTPDSDQPGARQR
DIVTFQSVMLDETPHNPYERVAAALVEASGQDRLMLHVVGHGREPVVEGVDPTRICGWFTTHTPIVLSGGLADVAGQLHA
MPRHGIAHGALRAYHPRGAELAVQDQVKILYNFFGETWDASFHGAVFEKPEEDLLYLKNHAFADNPADFWLYLVAVIHEG
KLQVRFQYSSVNYKEETIRGLADRMRESLKAHLNDPVAAPVAAPA

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI28416953, Length=563, Percent_Identity=22.3801065719361, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI115511026, Length=516, Percent_Identity=24.031007751938, Blast_Score=76, Evalue=3e-13,
Organism=Homo sapiens, GI42544132, Length=369, Percent_Identity=24.390243902439, Blast_Score=72, Evalue=5e-12,
Organism=Escherichia coli, GI1786801, Length=1066, Percent_Identity=25.891181988743, Blast_Score=257, Evalue=4e-69,
Organism=Escherichia coli, GI1786810, Length=520, Percent_Identity=25.9615384615385, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI145693145, Length=504, Percent_Identity=22.8174603174603, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17556356, Length=562, Percent_Identity=24.0213523131673, Blast_Score=132, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=563, Percent_Identity=23.9786856127886, Blast_Score=109, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32563687, Length=530, Percent_Identity=24.5283018867925, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560308, Length=419, Percent_Identity=26.491646778043, Blast_Score=101, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=526, Percent_Identity=23.574144486692, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564422, Length=535, Percent_Identity=22.0560747663551, Blast_Score=78, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32564420, Length=535, Percent_Identity=22.0560747663551, Blast_Score=78, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559526, Length=388, Percent_Identity=25.2577319587629, Blast_Score=72, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=971, Percent_Identity=25.1287332646756, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24648676, Length=645, Percent_Identity=26.3565891472868, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24581924, Length=365, Percent_Identity=26.3013698630137, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656500, Length=359, Percent_Identity=25.0696378830084, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 155942; Mature: 155942

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVTAPIPLAVVTQRIWLECKRAPDSSAYFVPFVYRLNPDIDPDRLEQALRETIAAHPA
CCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCHH
LRSVIREVEGKPYQVVLDTPARVLERSDSWEWAITKPFDVENGPLFRFVLCGDIFVLNGS
HHHHHHHHCCCCEEEEECCCHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECEEEEECCC
HMVLDGGSIMLLMEEVGARYHGEAVPEPGPGPAAWDAHERAYLDSPDHEADRAYWIEALA
EEEEECCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QSDFHAGLPTRRESYQGEKDGNLYFSLRLPQMNVSPFITTLALVQALIHRYTEQEMVAVL
HCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
YPTDLRGKPFARSMGSFVNTLIATASFTPELTFAQLVQQVQEQRRATREHDRLSFQEVIA
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GLRKARPSDGIQLPNVSVSWAKPLWPFTLGTPLPLETVDCQNDLLFLAFAEGERLDVRLQ
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEECCCCCEEEEEEECCCEEEEEEE
YQAAQFTRRFAEELAAHLSLLADAVSAQPDAPLSKLRLATEAEVQRIETERTPQPAPRPD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
LQLIHDAFSDWAERQPDAPALLMRERVVTYGEMERLTNRIAHGLRRRGVKPNTLVAVMME
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH
KGWEQAVACMAILKAGAGYLPINAAWPPERMDAVNAQGEVEIVLSQQRVLDRLGRPGLAV
HCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCEE
DDDALWADEPDTRLPSVNDIGDICYVLFTSGSTGKPKGVTLTHFSVMNTLRNANAEHGVG
CCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCCCCEEEEHHHHHHHHHCCCCCCCCC
PGDRSLQLSDFSFDLSVYDIFGMLSAGAGVVIPDEDRHLEPPHWVELVRQHQATIWLSVP
CCCCCEEEECCEECHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEEECH
MYVDMWVQSGEALPTIRVFMMGGDKIPTDLPDRMRPLAPDAVIWSVGGPTETSIISNWYR
HHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHH
IGAVDPIWTTIPYGRAMPNQKMLVLDPGLNHCPPFMPGRIFMGGVCLARGYWHDEEKTAA
CCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCCEE
AFITYPATGERIYYTGDLGRWLPDGQVEFLGRADFQVKVNGFRVELGEIEGAIEALPGVK
EEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEEEEEEEHHHHHHHHHHCCCCE
AAIVDGQDQPNRKGKFLVAYVVSEDALDAAEMRAALQDKLPYYMIPRVFVPLERIPLSAN
EEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEECCHHHCCHHHCCCCCC
GKVDRKALPRPDVAQMPGELPYVPPRTETEAALVDIWQAVLKHEPIGIHDNFYALGGDSL
CCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCE
LAVQLGIKAREVGLPLDPTALQRTPTIAELVQGLAPVKAVDASEATGDEPLSPMQRYYFT
EEEEECCCHHHCCCCCCCHHHCCCCCHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHEEE
WATERPQQFNVSAVFRCALEPERLRDALKTLVAHHDALRLRFHDGRQYYVETGIEVPLEC
EECCCCCCCCHHHHEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCC
ADIPLADVAARAAQMQETIDIAQGPIMRAGLFTTEDGQRLVLICHHLVTDGLSWGAVVTD
CCCCHHHHHHHHHHHHHHHHHHCCCCEECCEEECCCCCEEHHHHHHHHHCCCCHHHHHHH
LQRAYLGQPLAPAGGTYKAWVEGLISYAATPEAEAQFPYWLEQQGPTFTPDSDQPGARQR
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCH
DIVTFQSVMLDETPHNPYERVAAALVEASGQDRLMLHVVGHGREPVVEGVDPTRICGWFT
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHEEEEEE
THTPIVLSGGLADVAGQLHAMPRHGIAHGALRAYHPRGAELAVQDQVKILYNFFGETWDA
CCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCCC
SFHGAVFEKPEEDLLYLKNHAFADNPADFWLYLVAVIHEGKLQVRFQYSSVNYKEETIRG
CCCCHHCCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
LADRMRESLKAHLNDPVAAPVAAPA
HHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNVVTAPIPLAVVTQRIWLECKRAPDSSAYFVPFVYRLNPDIDPDRLEQALRETIAAHPA
CCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCHH
LRSVIREVEGKPYQVVLDTPARVLERSDSWEWAITKPFDVENGPLFRFVLCGDIFVLNGS
HHHHHHHHCCCCEEEEECCCHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECEEEEECCC
HMVLDGGSIMLLMEEVGARYHGEAVPEPGPGPAAWDAHERAYLDSPDHEADRAYWIEALA
EEEEECCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
QSDFHAGLPTRRESYQGEKDGNLYFSLRLPQMNVSPFITTLALVQALIHRYTEQEMVAVL
HCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
YPTDLRGKPFARSMGSFVNTLIATASFTPELTFAQLVQQVQEQRRATREHDRLSFQEVIA
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GLRKARPSDGIQLPNVSVSWAKPLWPFTLGTPLPLETVDCQNDLLFLAFAEGERLDVRLQ
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEECCCCCEEEEEEECCCEEEEEEE
YQAAQFTRRFAEELAAHLSLLADAVSAQPDAPLSKLRLATEAEVQRIETERTPQPAPRPD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
LQLIHDAFSDWAERQPDAPALLMRERVVTYGEMERLTNRIAHGLRRRGVKPNTLVAVMME
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH
KGWEQAVACMAILKAGAGYLPINAAWPPERMDAVNAQGEVEIVLSQQRVLDRLGRPGLAV
HCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCEE
DDDALWADEPDTRLPSVNDIGDICYVLFTSGSTGKPKGVTLTHFSVMNTLRNANAEHGVG
CCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCCCCEEEEHHHHHHHHHCCCCCCCCC
PGDRSLQLSDFSFDLSVYDIFGMLSAGAGVVIPDEDRHLEPPHWVELVRQHQATIWLSVP
CCCCCEEEECCEECHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEEECH
MYVDMWVQSGEALPTIRVFMMGGDKIPTDLPDRMRPLAPDAVIWSVGGPTETSIISNWYR
HHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHH
IGAVDPIWTTIPYGRAMPNQKMLVLDPGLNHCPPFMPGRIFMGGVCLARGYWHDEEKTAA
CCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCCEE
AFITYPATGERIYYTGDLGRWLPDGQVEFLGRADFQVKVNGFRVELGEIEGAIEALPGVK
EEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEEEEEEEHHHHHHHHHHCCCCE
AAIVDGQDQPNRKGKFLVAYVVSEDALDAAEMRAALQDKLPYYMIPRVFVPLERIPLSAN
EEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEECCHHHCCHHHCCCCCC
GKVDRKALPRPDVAQMPGELPYVPPRTETEAALVDIWQAVLKHEPIGIHDNFYALGGDSL
CCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCE
LAVQLGIKAREVGLPLDPTALQRTPTIAELVQGLAPVKAVDASEATGDEPLSPMQRYYFT
EEEEECCCHHHCCCCCCCHHHCCCCCHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHEEE
WATERPQQFNVSAVFRCALEPERLRDALKTLVAHHDALRLRFHDGRQYYVETGIEVPLEC
EECCCCCCCCHHHHEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCC
ADIPLADVAARAAQMQETIDIAQGPIMRAGLFTTEDGQRLVLICHHLVTDGLSWGAVVTD
CCCCHHHHHHHHHHHHHHHHHHCCCCEECCEEECCCCCEEHHHHHHHHHCCCCHHHHHHH
LQRAYLGQPLAPAGGTYKAWVEGLISYAATPEAEAQFPYWLEQQGPTFTPDSDQPGARQR
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCH
DIVTFQSVMLDETPHNPYERVAAALVEASGQDRLMLHVVGHGREPVVEGVDPTRICGWFT
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHEEEEEE
THTPIVLSGGLADVAGQLHAMPRHGIAHGALRAYHPRGAELAVQDQVKILYNFFGETWDA
CCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCCC
SFHGAVFEKPEEDLLYLKNHAFADNPADFWLYLVAVIHEGKLQVRFQYSSVNYKEETIRG
CCCCHHCCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
LADRMRESLKAHLNDPVAAPVAAPA
HHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA