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The map label for this gene is erg3 [H]

Identifier: 154244328

GI number: 154244328

Start: 386161

End: 387000

Strand: Reverse

Name: erg3 [H]

Synonym: Xaut_0371

Alternate gene names: 154244328

Gene position: 387000-386161 (Counterclockwise)

Preceding gene: 154244329

Following gene: 154244327

Centisome position: 7.29

GC content: 68.57

Gene sequence:

>840_bases
ATGGCCGGCTTCTTCACCGGTGGCGCCATCGCGTCCCAGTCCGGGGGCTTCGCACTGATCGCCCTCACCCTGATGGCGGC
GGAATACCTGTTCCACAAGGTGAACCATGTGGACAGCCATGACGCGGGGGAGAGCGGCGCCTCCCTTGCCATCGCGGCCG
GCAACAAGGTCATCGGCTCGCTCACCGCCTCGCTCGCCGCCGTGCCGGTGTTCTTTGTCTACCGGCACCGCCTGTTCGAC
ATTCCCATGCAGGGCGTCGCGCCCTGGGCCCTGCTCTTCCTGGCGGTGGAGTTCTGCTACTTCCTCCACCACCTCGCCAT
GCACAAGGTGCGCTGGCTGTGGGCGACCCATGCCGTGCACCACTCGGCGACCCGGCTCAACCTGTCGGCCGCGGTGCGGC
TCGGCTGGGGCGGCCAGCTCACCGGCGGGCTCGTGTTCTACCTGCCGCTGGTGGCGCTGGGCTTTCCGCCGCTAGCGGTG
TTCGGCATGCTGGGAGCCGGTCTCGTCTACCAGTTCTTCCTGCACCTCGCCCGGCCGCCCCATCTCGGCCCGCTGGAATG
GGTGCTGAACACCCCGCGCCACCATGCGGTGCACCACGCCGCCAACCCCAGCGTCATCGACCGCAATTTCGGCGGCGTCC
TCATCGTGTTCGACCGCCTGTTCGGCACCTTTGCCGAGGCCCCGCGAGGCGAGTCCCTGAGATTCGGCGTCGCCGGCGCC
ACCCCGAGCCGCAATCCACTGGTCATCGTGTTTTCCGAGTGGATCTCCATGCTCCGTGACGCATGGCGGACGCCCGGCCT
CGGCGGCAAGCTGCGCGTCCTGTTCGGACCTCCCGGGTAA

Upstream 100 bases:

>100_bases
CCACCGACCTCCACGGCGTCGGCACCGCTGCACCCGCGACACACGACCAGACCTGAAACCCGGGGTGCGGGGGCGCTCTC
GACAGTCAAGAGGTAAAGCC

Downstream 100 bases:

>100_bases
AATCGGTATCAGAGTGAAGCTTGCTCTGAATGGAATGCATTTCTGTATTGCGGAAAATGCGGATTGTGCATCGCAACAAT
CACGGTATGTTCATCGCAGA

Product: putative transmembrane fatty acid synthesis protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MAGFFTGGAIASQSGGFALIALTLMAAEYLFHKVNHVDSHDAGESGASLAIAAGNKVIGSLTASLAAVPVFFVYRHRLFD
IPMQGVAPWALLFLAVEFCYFLHHLAMHKVRWLWATHAVHHSATRLNLSAAVRLGWGGQLTGGLVFYLPLVALGFPPLAV
FGMLGAGLVYQFFLHLARPPHLGPLEWVLNTPRHHAVHHAANPSVIDRNFGGVLIVFDRLFGTFAEAPRGESLRFGVAGA
TPSRNPLVIVFSEWISMLRDAWRTPGLGGKLRVLFGPPG

Sequences:

>Translated_279_residues
MAGFFTGGAIASQSGGFALIALTLMAAEYLFHKVNHVDSHDAGESGASLAIAAGNKVIGSLTASLAAVPVFFVYRHRLFD
IPMQGVAPWALLFLAVEFCYFLHHLAMHKVRWLWATHAVHHSATRLNLSAAVRLGWGGQLTGGLVFYLPLVALGFPPLAV
FGMLGAGLVYQFFLHLARPPHLGPLEWVLNTPRHHAVHHAANPSVIDRNFGGVLIVFDRLFGTFAEAPRGESLRFGVAGA
TPSRNPLVIVFSEWISMLRDAWRTPGLGGKLRVLFGPPG
>Mature_278_residues
AGFFTGGAIASQSGGFALIALTLMAAEYLFHKVNHVDSHDAGESGASLAIAAGNKVIGSLTASLAAVPVFFVYRHRLFDI
PMQGVAPWALLFLAVEFCYFLHHLAMHKVRWLWATHAVHHSATRLNLSAAVRLGWGGQLTGGLVFYLPLVALGFPPLAVF
GMLGAGLVYQFFLHLARPPHLGPLEWVLNTPRHHAVHHAANPSVIDRNFGGVLIVFDRLFGTFAEAPRGESLRFGVAGAT
PSRNPLVIVFSEWISMLRDAWRTPGLGGKLRVLFGPPG

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=205, Percent_Identity=40, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25144659, Length=212, Percent_Identity=29.2452830188679, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 30128; Mature: 29996

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFFTGGAIASQSGGFALIALTLMAAEYLFHKVNHVDSHDAGESGASLAIAAGNKVIGS
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHH
LTASLAAVPVFFVYRHRLFDIPMQGVAPWALLFLAVEFCYFLHHLAMHKVRWLWATHAVH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSATRLNLSAAVRLGWGGQLTGGLVFYLPLVALGFPPLAVFGMLGAGLVYQFFLHLARPP
HHHHEEEHEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
HLGPLEWVLNTPRHHAVHHAANPSVIDRNFGGVLIVFDRLFGTFAEAPRGESLRFGVAGA
CCCHHHHHHCCCHHHHHHHCCCCCEEECCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECC
TPSRNPLVIVFSEWISMLRDAWRTPGLGGKLRVLFGPPG
CCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
AGFFTGGAIASQSGGFALIALTLMAAEYLFHKVNHVDSHDAGESGASLAIAAGNKVIGS
CCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHH
LTASLAAVPVFFVYRHRLFDIPMQGVAPWALLFLAVEFCYFLHHLAMHKVRWLWATHAVH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSATRLNLSAAVRLGWGGQLTGGLVFYLPLVALGFPPLAVFGMLGAGLVYQFFLHLARPP
HHHHEEEHEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
HLGPLEWVLNTPRHHAVHHAANPSVIDRNFGGVLIVFDRLFGTFAEAPRGESLRFGVAGA
CCCHHHHHHCCCHHHHHHHCCCCCEEECCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECC
TPSRNPLVIVFSEWISMLRDAWRTPGLGGKLRVLFGPPG
CCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]