Click here to switch to the map view.

The map label for this gene is aspB [H]

Identifier: 153951572

GI number: 153951572

Start: 1095560

End: 1096729

Strand: Direct

Name: aspB [H]

Synonym: JJD26997_1250

Alternate gene names: 153951572

Gene position: 1095560-1096729 (Clockwise)

Preceding gene: 153951619

Following gene: 153952524

Centisome position: 59.38

GC content: 34.7

Gene sequence:

>1170_bases
ATGCTTACAAAAAGATCTCAAGTTTTAGAAGAATCTATCACTTTAGCCATCACTGCACTTGCCAATGAACTTAAAGCTAA
AGGCGAAGATATCATTAGTTTTTCAGCAGGCGAACCTGATTTTGAGACGCCACAAGCCATCAAACATGCCGCTATAAGTG
CTATTGAAAAAGGGTGTGGAAAATATACTGCTGTTGCGGGAATTCCTGAAGTATTAAAAGCTATTCAAACCAAATTTAAA
AAAGACAACAATCTTGATTATGAAACAAGCGAAATCATCACCAATGTAGGTGCAAAACACTCTCTTTTTGAATGTATAGA
ATGCTTAGTAGAAAAAGATGATGAAGTAATTATCCCTAGTCCTTACTGGGTAAGTTATCCTGAAATGGTAAAATTTGCAG
GTGGAAAACCTGTATTTATAAAAGGTTTAGAAGAAAATGGCTTTAAAATTACCGCTGAACAACTAAAAAAAGCTATCACG
CCTAAAACCAAGGTTTTGATGCTAAATTCTCCTTCAAATCCTGTGGGATCGATTTATTCTAAAGAGGAATTAACTCAAAT
TGCTAAAGTTTTAGAAGGAACGCGAATCACTGTTTTAAGTGATGAAATGTATGAAAAACTTCGCTACGATGGTTTTGATT
TTGTAGCTTTTGCAAGCGTAAGCGAAGATGCTTTAAAACGCACTGTGACCATTAACGGACTTAGCAAATGTGGGGCTATG
CCAGGATGGCGTTTTGGCTATATGGCAAGCAAAAATAAAGCACTCATTTCAGCCGTTAAAAGACTTCAAGGACAAAGCAC
TTCAAATATTTGCTCCATCACCCAACATGCAGCCATTCCTGCATTAAATGGAGGATGTGATAAAGATATAGAAAAAATGC
GTCAAGCTTTTGAAAAACGCCGCGATTTAGCTCTAAATATGCTTAAACAAATCCCAAATATCAGTGTTTATAAACCAGAA
GGTGCTTTTTATCTTTTTGTAAATATACAAAAAATAGAAAAAGATTCTATGAAATTTTGCCAAAAATTACTTGAACAAGA
AAAAGTTGCCGTTGTTCCAGGTATAGGTTTTGGAATGGATGGATACTTTAGACTTTCTTATGCTATAAGCGATGAATTTA
TCAAGAAAGGTTTAGAAAGAATAGCTTATTTCATTGCGAATTACAAATAG

Upstream 100 bases:

>100_bases
TTTTCACATTATTGAAATTTATAACTCATTTTTAAATTAAATTTATTGTAAAAATGCAATTTTCTGCTAAAATTAAACAA
AAATTATTAAGGATTGAAAA

Downstream 100 bases:

>100_bases
TTACCATGAAAAGACCTTTACCTTTTATACTTGCAGCCACAAATAATGGAACTATGATTATCAACCATCTAGATAGACAT
GATACATCCCAAGGAAGTTA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFETPQAIKHAAISAIEKGCGKYTAVAGIPEVLKAIQTKFK
KDNNLDYETSEIITNVGAKHSLFECIECLVEKDDEVIIPSPYWVSYPEMVKFAGGKPVFIKGLEENGFKITAEQLKKAIT
PKTKVLMLNSPSNPVGSIYSKEELTQIAKVLEGTRITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGGCDKDIEKMRQAFEKRRDLALNMLKQIPNISVYKPE
GAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGMDGYFRLSYAISDEFIKKGLERIAYFIANYK

Sequences:

>Translated_389_residues
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFETPQAIKHAAISAIEKGCGKYTAVAGIPEVLKAIQTKFK
KDNNLDYETSEIITNVGAKHSLFECIECLVEKDDEVIIPSPYWVSYPEMVKFAGGKPVFIKGLEENGFKITAEQLKKAIT
PKTKVLMLNSPSNPVGSIYSKEELTQIAKVLEGTRITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGGCDKDIEKMRQAFEKRRDLALNMLKQIPNISVYKPE
GAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGMDGYFRLSYAISDEFIKKGLERIAYFIANYK
>Mature_389_residues
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFETPQAIKHAAISAIEKGCGKYTAVAGIPEVLKAIQTKFK
KDNNLDYETSEIITNVGAKHSLFECIECLVEKDDEVIIPSPYWVSYPEMVKFAGGKPVFIKGLEENGFKITAEQLKKAIT
PKTKVLMLNSPSNPVGSIYSKEELTQIAKVLEGTRITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGGCDKDIEKMRQAFEKRRDLALNMLKQIPNISVYKPE
GAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGMDGYFRLSYAISDEFIKKGLERIAYFIANYK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=26.8733850129199, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=26.8733850129199, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI95147551, Length=332, Percent_Identity=26.5060240963855, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI169881279, Length=332, Percent_Identity=26.5060240963855, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4507369, Length=400, Percent_Identity=24.25, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=26.6949152542373, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1788627, Length=383, Percent_Identity=26.6318537859008, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788722, Length=355, Percent_Identity=30.1408450704225, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=25.3926701570681, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787909, Length=357, Percent_Identity=21.8487394957983, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787710, Length=312, Percent_Identity=19.5512820512821, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=347, Percent_Identity=26.5129682997118, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=416, Percent_Identity=25.9615384615385, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=416, Percent_Identity=25.9615384615385, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=379, Percent_Identity=28.4960422163588, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.9074550128535, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=387, Percent_Identity=24.031007751938, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=24.21875, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28573069, Length=352, Percent_Identity=25, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646114, Length=352, Percent_Identity=25, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573067, Length=352, Percent_Identity=25, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573065, Length=352, Percent_Identity=25, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641770, Length=402, Percent_Identity=26.6169154228856, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641760, Length=402, Percent_Identity=26.6169154228856, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641768, Length=402, Percent_Identity=26.6169154228856, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641766, Length=402, Percent_Identity=26.6169154228856, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641764, Length=402, Percent_Identity=26.6169154228856, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45551451, Length=402, Percent_Identity=26.6169154228856, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43218; Mature: 43218

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFETPQAIKHAAISAIEKGCG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCC
KYTAVAGIPEVLKAIQTKFKKDNNLDYETSEIITNVGAKHSLFECIECLVEKDDEVIIPS
CHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECCC
PYWVSYPEMVKFAGGKPVFIKGLEENGFKITAEQLKKAITPKTKVLMLNSPSNPVGSIYS
CCCCCCHHHHHHCCCCEEEEEECCCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCCCC
KEELTQIAKVLEGTRITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
HHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCEEEEECCCHHHHHHEEEECCHHHHCCC
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGGCDKDIEKMRQAFEKR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
RDLALNMLKQIPNISVYKPEGAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGMD
HHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
GYFRLSYAISDEFIKKGLERIAYFIANYK
CEEEEEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFETPQAIKHAAISAIEKGCG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCC
KYTAVAGIPEVLKAIQTKFKKDNNLDYETSEIITNVGAKHSLFECIECLVEKDDEVIIPS
CHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECCC
PYWVSYPEMVKFAGGKPVFIKGLEENGFKITAEQLKKAITPKTKVLMLNSPSNPVGSIYS
CCCCCCHHHHHHCCCCEEEEEECCCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCCCC
KEELTQIAKVLEGTRITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
HHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCEEEEECCCHHHHHHEEEECCHHHHCCC
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGGCDKDIEKMRQAFEKR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
RDLALNMLKQIPNISVYKPEGAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGMD
HHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
GYFRLSYAISDEFIKKGLERIAYFIANYK
CEEEEEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]