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The map label for this gene is hemN [H]

Identifier: 153951392

GI number: 153951392

Start: 961302

End: 962369

Strand: Direct

Name: hemN [H]

Synonym: JJD26997_1089

Alternate gene names: 153951392

Gene position: 961302-962369 (Clockwise)

Preceding gene: 153952193

Following gene: 153951649

Centisome position: 52.1

GC content: 26.5

Gene sequence:

>1068_bases
ATGCATTTTTATATCCACATTCCATTTTGTGAAAGCAAATGTAATTATTGCGCTTTTACAAGTTTGAAAAAAAATGATTA
TGAAAAAGCCTATTTTAAGGCTTTAAAAAAAGATATTATTTTTCAATTAAAACAATTTAACATTCAATCAAATCAAATTA
AAACCTTATTTATAGGCGGAGGAACGCCAAGTTGTGTCGATGCGTATAATTATGAAGATATTTTTAAAATTTTATATCCC
TTACTAGATAAAAATGTAGAAATTTCATGCGAAGCTAATCCCAACTCAGCAACATTAAATTGGCTTAAAAATATGAAAAA
TCTAGGAGTTAATCGCATTTCTTTTGGAGCTCAAAGTTTTCATCCTAAAAAACTTCACTTTCTTGGAAGAATTCACAATC
AAGAAATGATTATCAAAGCATTAGAAAACGCAAATAAAGCAGGTTTTAAAAATATCAATTTAGATCTTATTTATGATACG
AAATTAGACAATAAAAAAATGCTTGAATTTGAACTCTTGCACTTGAAAAAAATCAAGGCTTTAATCACGCACCTTAGTGC
TTATAATTTAACCATAGAATCAAACACAGCCTTTGCCAAAAAAGAACATTTCAAAAAAAATGCTCCTAATTTAATAAAAT
TTTTTATCAAACAACTTCTAGAACTTGACTTTTTTCAATATGAAATCAGCAATTTTTCAAAAACTAAATCCCAAATTTGC
AAACATAATCTTGCTTATTGGCAAGGAAAAAACTACCTAGCTTGTGGATTAAGCGCGGTAGGATTTTATGAAAATAAGCG
TTTTTATACAGCAAAAAATTTAAAAAATTACATAGAAAATCCTACTTTTAGATCTATAGAGCAACTAAGTTCTAAAGACT
TGAATTTAGAACACCTATTTTTAGGACTTAGAAGTATAGTAGGGATTGATGAAACAAAACTCAATCAATGGCAAAAAGAC
AAAATAAATATATTATTAAAAGAAAAAAAACTTTTTTACAAAAATAAAAGATATTTTAATCCTAATTTTCTCATTAGCGA
TGAACTTGCTTTATATCTCTCATCTTAA

Upstream 100 bases:

>100_bases
CAATATTGTTCCTTAATTTTAAGGATATAATTTTAATCTAAATCAAATCAAATTTTTATTAAAATACATTAAAAATTTAA
TAAAATATTTTAGGGTTTTT

Downstream 100 bases:

>100_bases
ATTTAAGTTTTTTAAGTAAAATATTTATTTAAAATATCAAAATCAAAGAGTAATGATTAATGAGTTTTGGTGAAATTATA
GTTATTTTAGTTGTAGCGAT

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKKDIIFQLKQFNIQSNQIKTLFIGGGTPSCVDAYNYEDIFKILYP
LLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGAQSFHPKKLHFLGRIHNQEMIIKALENANKAGFKNINLDLIYDT
KLDNKKMLEFELLHLKKIKALITHLSAYNLTIESNTAFAKKEHFKKNAPNLIKFFIKQLLELDFFQYEISNFSKTKSQIC
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLFLGLRSIVGIDETKLNQWQKD
KINILLKEKKLFYKNKRYFNPNFLISDELALYLSS

Sequences:

>Translated_355_residues
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKKDIIFQLKQFNIQSNQIKTLFIGGGTPSCVDAYNYEDIFKILYP
LLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGAQSFHPKKLHFLGRIHNQEMIIKALENANKAGFKNINLDLIYDT
KLDNKKMLEFELLHLKKIKALITHLSAYNLTIESNTAFAKKEHFKKNAPNLIKFFIKQLLELDFFQYEISNFSKTKSQIC
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLFLGLRSIVGIDETKLNQWQKD
KINILLKEKKLFYKNKRYFNPNFLISDELALYLSS
>Mature_355_residues
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKKDIIFQLKQFNIQSNQIKTLFIGGGTPSCVDAYNYEDIFKILYP
LLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGAQSFHPKKLHFLGRIHNQEMIIKALENANKAGFKNINLDLIYDT
KLDNKKMLEFELLHLKKIKALITHLSAYNLTIESNTAFAKKEHFKKNAPNLIKFFIKQLLELDFFQYEISNFSKTKSQIC
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLFLGLRSIVGIDETKLNQWQKD
KINILLKEKKLFYKNKRYFNPNFLISDELALYLSS

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=275, Percent_Identity=29.8181818181818, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1789325, Length=289, Percent_Identity=34.6020761245675, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI87082341, Length=193, Percent_Identity=27.979274611399, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 41585; Mature: 41585

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKKDIIFQLKQFNIQSNQIKTLFIGG
CEEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GTPSCVDAYNYEDIFKILYPLLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGAQSF
CCCHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCC
HPKKLHFLGRIHNQEMIIKALENANKAGFKNINLDLIYDTKLDNKKMLEFELLHLKKIKA
CCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LITHLSAYNLTIESNTAFAKKEHFKKNAPNLIKFFIKQLLELDFFQYEISNFSKTKSQIC
HHHHHHHEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLF
HCCCCEECCCCEEEECCHHHCEECCCEEEEHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
LGLRSIVGIDETKLNQWQKDKINILLKEKKLFYKNKRYFNPNFLISDELALYLSS
HHHHHHHCCCHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEECCCEEEEECC
>Mature Secondary Structure
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKKDIIFQLKQFNIQSNQIKTLFIGG
CEEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GTPSCVDAYNYEDIFKILYPLLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGAQSF
CCCHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCC
HPKKLHFLGRIHNQEMIIKALENANKAGFKNINLDLIYDTKLDNKKMLEFELLHLKKIKA
CCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LITHLSAYNLTIESNTAFAKKEHFKKNAPNLIKFFIKQLLELDFFQYEISNFSKTKSQIC
HHHHHHHEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLF
HCCCCEECCCCEEEECCHHHCEECCCEEEEHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
LGLRSIVGIDETKLNQWQKDKINILLKEKKLFYKNKRYFNPNFLISDELALYLSS
HHHHHHHCCCHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]