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The map label for this gene is lepB [H]

Identifier: 153951289

GI number: 153951289

Start: 884934

End: 885785

Strand: Direct

Name: lepB [H]

Synonym: JJD26997_1005

Alternate gene names: 153951289

Gene position: 884934-885785 (Clockwise)

Preceding gene: 153952430

Following gene: 153951868

Centisome position: 47.96

GC content: 31.92

Gene sequence:

>852_bases
ATGGAAATTTTAAAGAAATTATATAAATTTTCGCAGTCTTGGACTGGAACTGTAGTTATTGTTCTTTTGGTGATTTTTTT
CTTTATACAAGCTTTTGTTATTCCTTCTCGTTCTATGAAAAACACCTTATTAGTGGGGGATTTTTTATTTGTTAAAAAAT
TTAGCTATGGTATCCCAACTCCTCATATTCCTTGGTTGGAAATTCCTGTTTTGCCGGATTTTAATAAAGATGGACATTTG
ATAAAAGCACAAGGGCCACAAAGAGGTGATATAGTTGTTTTTAGAAATCCTAGAAATGAAAAACAACACTTTGTAAAGCG
TTGTGTAGGCATAGGGGGAGATAGGATAATTTATGCAAATAAAACACTTTATGTAAGAATGCATGAGGGTGATGATTTTA
TGAAAGAACATTATCCGAATGATCTTGTTATTCTTGGAGGGCAAATTTATATAAAAGAACCTTATAAACAAAAAGGTATT
CATTATGATCCAAAAAAAGATATAGAAAGTAATATTTTACGCTTTCTTAGCATAGGTGATTTTGCTATGTCTCCAACTTA
TATTAAAGAACTTGGAAATCATATAGGTTTTAGCGGCAGAAATGCTTATGTTTTTGATGTACCTGAAAATGAGTATTTCA
TGATGGGTGATAATCGTGATCATTCTGAGGATAGTCGTTTTTGGGGTTCTGTTCCTTATAGGTTGATAGTAGGTAAACCT
TGGTTTGTATATTTCTCTTGGGATAAAGATAAAAATGTTCGCTGGGAAAGGATAGGGCGTTTTGTTGATACCTTGGAAAA
TGATGAACAATATATCCATGATCATGATGATGATGAGGATAAATTAAGCTAA

Upstream 100 bases:

>100_bases
TATAACTCCTGTTCCATGTGGAGTAGGTCCTATGACTATAGCTATGCTTTTAGAAAACACAGTTAAATCTGCTAAAAATA
GACTTAATTAGGAAAAATCT

Downstream 100 bases:

>100_bases
TGTTTGTGAAAAACACAAACATTATATTTTTAAAAGTGTGATTTCATCACCTTTTTTTAATTCGCTTGTATTTTCTTCAC
TTATAAGTAAAAACTCACTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MEILKKLYKFSQSWTGTVVIVLLVIFFFIQAFVIPSRSMKNTLLVGDFLFVKKFSYGIPTPHIPWLEIPVLPDFNKDGHL
IKAQGPQRGDIVVFRNPRNEKQHFVKRCVGIGGDRIIYANKTLYVRMHEGDDFMKEHYPNDLVILGGQIYIKEPYKQKGI
HYDPKKDIESNILRFLSIGDFAMSPTYIKELGNHIGFSGRNAYVFDVPENEYFMMGDNRDHSEDSRFWGSVPYRLIVGKP
WFVYFSWDKDKNVRWERIGRFVDTLENDEQYIHDHDDDEDKLS

Sequences:

>Translated_283_residues
MEILKKLYKFSQSWTGTVVIVLLVIFFFIQAFVIPSRSMKNTLLVGDFLFVKKFSYGIPTPHIPWLEIPVLPDFNKDGHL
IKAQGPQRGDIVVFRNPRNEKQHFVKRCVGIGGDRIIYANKTLYVRMHEGDDFMKEHYPNDLVILGGQIYIKEPYKQKGI
HYDPKKDIESNILRFLSIGDFAMSPTYIKELGNHIGFSGRNAYVFDVPENEYFMMGDNRDHSEDSRFWGSVPYRLIVGKP
WFVYFSWDKDKNVRWERIGRFVDTLENDEQYIHDHDDDEDKLS
>Mature_283_residues
MEILKKLYKFSQSWTGTVVIVLLVIFFFIQAFVIPSRSMKNTLLVGDFLFVKKFSYGIPTPHIPWLEIPVLPDFNKDGHL
IKAQGPQRGDIVVFRNPRNEKQHFVKRCVGIGGDRIIYANKTLYVRMHEGDDFMKEHYPNDLVILGGQIYIKEPYKQKGI
HYDPKKDIESNILRFLSIGDFAMSPTYIKELGNHIGFSGRNAYVFDVPENEYFMMGDNRDHSEDSRFWGSVPYRLIVGKP
WFVYFSWDKDKNVRWERIGRFVDTLENDEQYIHDHDDDEDKLS

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=270, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 33272; Mature: 33272

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILKKLYKFSQSWTGTVVIVLLVIFFFIQAFVIPSRSMKNTLLVGDFLFVKKFSYGIPT
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCCCCC
PHIPWLEIPVLPDFNKDGHLIKAQGPQRGDIVVFRNPRNEKQHFVKRCVGIGGDRIIYAN
CCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEC
KTLYVRMHEGDDFMKEHYPNDLVILGGQIYIKEPYKQKGIHYDPKKDIESNILRFLSIGD
CEEEEEEECCCHHHHHHCCCCEEEECCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCC
FAMSPTYIKELGNHIGFSGRNAYVFDVPENEYFMMGDNRDHSEDSRFWGSVPYRLIVGKP
CCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCEECCCCEEEEECCE
WFVYFSWDKDKNVRWERIGRFVDTLENDEQYIHDHDDDEDKLS
EEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCHHCCC
>Mature Secondary Structure
MEILKKLYKFSQSWTGTVVIVLLVIFFFIQAFVIPSRSMKNTLLVGDFLFVKKFSYGIPT
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCCCCC
PHIPWLEIPVLPDFNKDGHLIKAQGPQRGDIVVFRNPRNEKQHFVKRCVGIGGDRIIYAN
CCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEC
KTLYVRMHEGDDFMKEHYPNDLVILGGQIYIKEPYKQKGIHYDPKKDIESNILRFLSIGD
CEEEEEEECCCHHHHHHCCCCEEEECCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCC
FAMSPTYIKELGNHIGFSGRNAYVFDVPENEYFMMGDNRDHSEDSRFWGSVPYRLIVGKP
CCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCEECCCCEEEEECCE
WFVYFSWDKDKNVRWERIGRFVDTLENDEQYIHDHDDDEDKLS
EEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]