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The map label for this gene is murF [H]

Identifier: 153951182

GI number: 153951182

Start: 1066253

End: 1067680

Strand: Direct

Name: murF [H]

Synonym: JJD26997_1216

Alternate gene names: 153951182

Gene position: 1066253-1067680 (Clockwise)

Preceding gene: 153952209

Following gene: 153952409

Centisome position: 57.79

GC content: 28.71

Gene sequence:

>1428_bases
ATGCTTATCAACACTCTTTATTTTATCAATTCTTTATTTTTTAATTTTTGTATAGCTTTTTATCTTATGAGTGCTTTACA
ATGGTATTCTTATAAATTTAAACGCGTGTTTTTTCATTATCATAAACCTTTGTGGCATTTGTATTTTTTATTTATTCCTT
ATTTTTTATTCTTAGCTTTTCCTTTATACTCTTTAGCATATTTTGCATTGATTCATGCTCCGATTTTGTATTTTTGGAAC
AAAGGTATAGATAAAAAGCTTGTTTTTACAAGTAAAGTTAAATGGTTTTTTGTTTTTGTTTTTGTTTATAATGCTATTTT
TGCTATCTTTGCTTTGCGTTTTTCTTTTCTTTTTAATCTTTTTAGCCTTCCTTTTGCTTTATTTAGTCTTAAAATTTATG
AGTTTTTTACAAATTTACATTACAAAAAACAAGCCAAAGCCAAACTAAAAGCCAATGAAAATTTAAAAATCATACTCATT
ACCGCAAGTTTTGGAAAAACAAGTATTAAAAATTTTTTATACGAACTTTTAAAAGATGACTTTAAAAGCTACAAAACACC
ACGCTCTGTCAATACTCTACTAGGTATAGTTGCTGATATCAATACCAATTTAAGTCAAGATGCTCAAATTTACATAGCTG
AAGCAGGTGCTAGACTTAAAGGCGATATCGATGAAATCACGCGTTTTTTACAACCTCATATCAGCATAGTAGGAGAGATA
GGCAATGCACATTTAGAGTACTTTAAAAGTGTTGAAAATATCCGCTCAACCAAACTTGAAGCCTTAAATTCCAAAAGATT
AGAGAAGGCTTTTTTACACTCTAGTACCCAAAAAAAAGAAGATAAACTCATCAGCCTTTATGATGATAAATTAAACCTTA
TTCATTCAAGTCTTGAAGGTTTAGAATTTAGGGTAAATATGGAAAGTAAATCTTATGATTTTAAAAGTCAAATTTTAGGG
GATTTTAATGCGCAAAATCTTTGTGTTTGTATACTTTGCGCTCATTATTTTGACATAAAGCTAGAAAAAATTCAAAAGCA
AGTTTTAAATATAAATTCCGTAGAACATCGCTTACAAGTGCTTTCAAGAGAGCCTAAATTTATCATAGATGATGGTTTTA
ATGGAAATTTTAAAGGTATGAGCACAAGCTATGAACTTTGTAAAAACTATAAAGGACGCAAAGTTTTAGTAAGTCCTGGC
ATAGTGGAAGTAAGCGAAGAAGAAAATATAAAACTTGCTAAAATCATCAATGAGTGTTTTGATCTTGCTATCATTAGCGC
ACAAATCAATGCTGAAATTTTTAAAAGAGAATTAAAAATTCCAACCATCATTTTAAAGGAAAAAAGCGAACTTATACAAA
CCTTAGCCAAAGAGACTAAAAACGGAGATTTAATACTCTTTTCAAACGATGCACCTAGTTTTATGTGA

Upstream 100 bases:

>100_bases
TAAGCTTTTAAAAAATAGCACTTTTTATCCTTTAGAGGGGGATCATTTTTTCTTTTTAAAACATTCTGCTTTCATAGCTC
AAAAAATCAAGGAAATTTAA

Downstream 100 bases:

>100_bases
TTCGCATAGTGGAGTGAAATTTAATGGTTGTAAGCCTATATTGAAACATTCCTAATTGTTCTGCTTCATTATACTGCTCT
TGTGTATTATAATAGTTTTT

Product: Mur ligase family protein

Products: NA

Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MLINTLYFINSLFFNFCIAFYLMSALQWYSYKFKRVFFHYHKPLWHLYFLFIPYFLFLAFPLYSLAYFALIHAPILYFWN
KGIDKKLVFTSKVKWFFVFVFVYNAIFAIFALRFSFLFNLFSLPFALFSLKIYEFFTNLHYKKQAKAKLKANENLKIILI
TASFGKTSIKNFLYELLKDDFKSYKTPRSVNTLLGIVADINTNLSQDAQIYIAEAGARLKGDIDEITRFLQPHISIVGEI
GNAHLEYFKSVENIRSTKLEALNSKRLEKAFLHSSTQKKEDKLISLYDDKLNLIHSSLEGLEFRVNMESKSYDFKSQILG
DFNAQNLCVCILCAHYFDIKLEKIQKQVLNINSVEHRLQVLSREPKFIIDDGFNGNFKGMSTSYELCKNYKGRKVLVSPG
IVEVSEEENIKLAKIINECFDLAIISAQINAEIFKRELKIPTIILKEKSELIQTLAKETKNGDLILFSNDAPSFM

Sequences:

>Translated_475_residues
MLINTLYFINSLFFNFCIAFYLMSALQWYSYKFKRVFFHYHKPLWHLYFLFIPYFLFLAFPLYSLAYFALIHAPILYFWN
KGIDKKLVFTSKVKWFFVFVFVYNAIFAIFALRFSFLFNLFSLPFALFSLKIYEFFTNLHYKKQAKAKLKANENLKIILI
TASFGKTSIKNFLYELLKDDFKSYKTPRSVNTLLGIVADINTNLSQDAQIYIAEAGARLKGDIDEITRFLQPHISIVGEI
GNAHLEYFKSVENIRSTKLEALNSKRLEKAFLHSSTQKKEDKLISLYDDKLNLIHSSLEGLEFRVNMESKSYDFKSQILG
DFNAQNLCVCILCAHYFDIKLEKIQKQVLNINSVEHRLQVLSREPKFIIDDGFNGNFKGMSTSYELCKNYKGRKVLVSPG
IVEVSEEENIKLAKIINECFDLAIISAQINAEIFKRELKIPTIILKEKSELIQTLAKETKNGDLILFSNDAPSFM
>Mature_475_residues
MLINTLYFINSLFFNFCIAFYLMSALQWYSYKFKRVFFHYHKPLWHLYFLFIPYFLFLAFPLYSLAYFALIHAPILYFWN
KGIDKKLVFTSKVKWFFVFVFVYNAIFAIFALRFSFLFNLFSLPFALFSLKIYEFFTNLHYKKQAKAKLKANENLKIILI
TASFGKTSIKNFLYELLKDDFKSYKTPRSVNTLLGIVADINTNLSQDAQIYIAEAGARLKGDIDEITRFLQPHISIVGEI
GNAHLEYFKSVENIRSTKLEALNSKRLEKAFLHSSTQKKEDKLISLYDDKLNLIHSSLEGLEFRVNMESKSYDFKSQILG
DFNAQNLCVCILCAHYFDIKLEKIQKQVLNINSVEHRLQVLSREPKFIIDDGFNGNFKGMSTSYELCKNYKGRKVLVSPG
IVEVSEEENIKLAKIINECFDLAIISAQINAEIFKRELKIPTIILKEKSELIQTLAKETKNGDLILFSNDAPSFM

Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]

COG id: COG0770

COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR005863 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.10 [H]

Molecular weight: Translated: 55340; Mature: 55340

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINTLYFINSLFFNFCIAFYLMSALQWYSYKFKRVFFHYHKPLWHLYFLFIPYFLFLAF
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLYSLAYFALIHAPILYFWNKGIDKKLVFTSKVKWFFVFVFVYNAIFAIFALRFSFLFNL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLPFALFSLKIYEFFTNLHYKKQAKAKLKANENLKIILITASFGKTSIKNFLYELLKDD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
FKSYKTPRSVNTLLGIVADINTNLSQDAQIYIAEAGARLKGDIDEITRFLQPHISIVGEI
HHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
GNAHLEYFKSVENIRSTKLEALNSKRLEKAFLHSSTQKKEDKLISLYDDKLNLIHSSLEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
LEFRVNMESKSYDFKSQILGDFNAQNLCVCILCAHYFDIKLEKIQKQVLNINSVEHRLQV
CEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LSREPKFIIDDGFNGNFKGMSTSYELCKNYKGRKVLVSPGIVEVSEEENIKLAKIINECF
HCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEECCCEEEECCCCCCHHHHHHHHHH
DLAIISAQINAEIFKRELKIPTIILKEKSELIQTLAKETKNGDLILFSNDAPSFM
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MLINTLYFINSLFFNFCIAFYLMSALQWYSYKFKRVFFHYHKPLWHLYFLFIPYFLFLAF
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLYSLAYFALIHAPILYFWNKGIDKKLVFTSKVKWFFVFVFVYNAIFAIFALRFSFLFNL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLPFALFSLKIYEFFTNLHYKKQAKAKLKANENLKIILITASFGKTSIKNFLYELLKDD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
FKSYKTPRSVNTLLGIVADINTNLSQDAQIYIAEAGARLKGDIDEITRFLQPHISIVGEI
HHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
GNAHLEYFKSVENIRSTKLEALNSKRLEKAFLHSSTQKKEDKLISLYDDKLNLIHSSLEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
LEFRVNMESKSYDFKSQILGDFNAQNLCVCILCAHYFDIKLEKIQKQVLNINSVEHRLQV
CEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LSREPKFIIDDGFNGNFKGMSTSYELCKNYKGRKVLVSPGIVEVSEEENIKLAKIINECF
HCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEECCCEEEECCCCCCHHHHHHHHHH
DLAIISAQINAEIFKRELKIPTIILKEKSELIQTLAKETKNGDLILFSNDAPSFM
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]