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The map label for this gene is yclF [H]

Identifier: 153951072

GI number: 153951072

Start: 1185708

End: 1187231

Strand: Direct

Name: yclF [H]

Synonym: JJD26997_1344

Alternate gene names: 153951072

Gene position: 1185708-1187231 (Clockwise)

Preceding gene: 153951489

Following gene: 153951626

Centisome position: 64.26

GC content: 31.76

Gene sequence:

>1524_bases
TTGAGTAAAAATATAAAAAATTTAGATACTTCATTTTTTGGACACCCAAAGCCACTTTTATCTCTTTCGTTCACTGAGCT
TTGGGAAAGATTTTCTTTTTACGGAATTCGTCCCTTGCTTGTTCTTTTTATATCAGCAGCTATTGTTTATGGTGGCTTAG
GCATAGAAAGAGAGAATGCCTCTGCCATAGTCGGTATTTTTGGGGGTTGTTTATATCTTGCATCTTTGCCAGGTGGATGG
CTTGCGGATAATTACTTAGGACAAAAAAGAGCAATTTTACTAGGTGCTTTAACTATAGCTTTAGGTCATTTATGTATAGC
TTTATCTATATTTCATTCTTTTATGTTTTTTCTAGGACTTGCTTTAATTGTCATAGGCACAGGACTTTTTAAAACTTGTG
CTTCTGTAATGGTTGGCATGCTTTATAAAAAAGATGATACAAGGCGTGATTCTGGTTTTACTCTTTTTTATATGGGTATT
AATATTGGAGCTTTTATTGCTCCTTTAATTTGCGGCTTTTTGCAAAAAGAATACGGATGGCATTTTGGTTTTGGTGCGGG
TGGGATTGGTATGCTCTTAGCAGTAATTATTTTCTACCTAAAAACCATGCCTGATTTAAAAGAATTTGATGAAAAAATTG
GTTTAGAGTATGATTGGAAAAGGGCTACTAAGAAAACTCAGAATATTAAATGGATCTTTTTTGGTTTAATATTTTGCCTA
GTCCTTTTAACTTTTATCGGCTATACGCTTTCATCTTTAGGACTGCTAGATCTAAGTCCTGTTTCTTTATCAAAAAAAAT
GATTTTTATCATACTTATTTGCACAGGAATTTATTTTTTATATCTTTTCTTTTTTAGTTCTTTAAATTCAATAGAAAAGA
AAAATTTAATAGTATTTATTATATTGTTTTTTGCTGCAGCATTTTTCTGGAGCACTTTTGAGCAAAAACCTACTTCTTTT
AATCTTTTTGCTCAAGATTTTACAAATAAAATTATATTTGGATGGGAAATTCCAACTCCATGGTTTCAATCTTTTAATCC
TTTATTTGTCATTATTTTTGCACCTATTATGGCCACAATTTGGATTTTTTTGGCTAAACATAAATTAGAACTTTCCTCTA
TAAGCAAATTTGCATTAGGAGTCTTAAGTGCTGGGATTGGATTTATGATTATGATGTTTGCAGCAAAAAATGTCTTGGCT
AGTAATGGTGCTCCCGTATCCATGATTTATATTATAAGCAGTATTTGGTTTTTAACACTTGGGGAACTCTGTCTTTCACC
TGTTGGGCTTTCAATAATGACAAAAATTGCTCCGAAATTAATTAAAAATCAAGTTATGGGACTTTGGTTTGTAGCAAGTG
CTTTAGGCAATGTTATAGCAGGGCTTATAGGAGGTCATGTCGATGCTAAAAATATAGCATCTTTACCTGATTTATTTGGG
CAATGTATGTGGGTTTTGTTCATCATGAGTGCAGTTTTATTTTTAATTAAAAAACCTGTTTATAATATGTTGAATAAGGA
GTGA

Upstream 100 bases:

>100_bases
AACATTTATGATATAAATCATTTAAAAATATTACAAAGTTATACATATTTTTTAATTTCTTGTCTATAATTTATAAATAA
AAATACACAAAGGATATAAA

Downstream 100 bases:

>100_bases
AAATGAAGGGGACTCAGAATTTAGATACTTCATTTTTTGGACATCCAAAACCACTTTTATCTCTTTCACTTGCTGAGCTT
TGGGAAAGATTTTCTTTTTA

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSKNIKNLDTSFFGHPKPLLSLSFTELWERFSFYGIRPLLVLFISAAIVYGGLGIERENASAIVGIFGGCLYLASLPGGW
LADNYLGQKRAILLGALTIALGHLCIALSIFHSFMFFLGLALIVIGTGLFKTCASVMVGMLYKKDDTRRDSGFTLFYMGI
NIGAFIAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKIGLEYDWKRATKKTQNIKWIFFGLIFCL
VLLTFIGYTLSSLGLLDLSPVSLSKKMIFIILICTGIYFLYLFFFSSLNSIEKKNLIVFIILFFAAAFFWSTFEQKPTSF
NLFAQDFTNKIIFGWEIPTPWFQSFNPLFVIIFAPIMATIWIFLAKHKLELSSISKFALGVLSAGIGFMIMMFAAKNVLA
SNGAPVSMIYIISSIWFLTLGELCLSPVGLSIMTKIAPKLIKNQVMGLWFVASALGNVIAGLIGGHVDAKNIASLPDLFG
QCMWVLFIMSAVLFLIKKPVYNMLNKE

Sequences:

>Translated_507_residues
MSKNIKNLDTSFFGHPKPLLSLSFTELWERFSFYGIRPLLVLFISAAIVYGGLGIERENASAIVGIFGGCLYLASLPGGW
LADNYLGQKRAILLGALTIALGHLCIALSIFHSFMFFLGLALIVIGTGLFKTCASVMVGMLYKKDDTRRDSGFTLFYMGI
NIGAFIAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKIGLEYDWKRATKKTQNIKWIFFGLIFCL
VLLTFIGYTLSSLGLLDLSPVSLSKKMIFIILICTGIYFLYLFFFSSLNSIEKKNLIVFIILFFAAAFFWSTFEQKPTSF
NLFAQDFTNKIIFGWEIPTPWFQSFNPLFVIIFAPIMATIWIFLAKHKLELSSISKFALGVLSAGIGFMIMMFAAKNVLA
SNGAPVSMIYIISSIWFLTLGELCLSPVGLSIMTKIAPKLIKNQVMGLWFVASALGNVIAGLIGGHVDAKNIASLPDLFG
QCMWVLFIMSAVLFLIKKPVYNMLNKE
>Mature_506_residues
SKNIKNLDTSFFGHPKPLLSLSFTELWERFSFYGIRPLLVLFISAAIVYGGLGIERENASAIVGIFGGCLYLASLPGGWL
ADNYLGQKRAILLGALTIALGHLCIALSIFHSFMFFLGLALIVIGTGLFKTCASVMVGMLYKKDDTRRDSGFTLFYMGIN
IGAFIAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKIGLEYDWKRATKKTQNIKWIFFGLIFCLV
LLTFIGYTLSSLGLLDLSPVSLSKKMIFIILICTGIYFLYLFFFSSLNSIEKKNLIVFIILFFAAAFFWSTFEQKPTSFN
LFAQDFTNKIIFGWEIPTPWFQSFNPLFVIIFAPIMATIWIFLAKHKLELSSISKFALGVLSAGIGFMIMMFAAKNVLAS
NGAPVSMIYIISSIWFLTLGELCLSPVGLSIMTKIAPKLIKNQVMGLWFVASALGNVIAGLIGGHVDAKNIASLPDLFGQ
CMWVLFIMSAVLFLIKKPVYNMLNKE

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=419, Percent_Identity=23.3890214797136, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI226371746, Length=384, Percent_Identity=23.6979166666667, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI226371748, Length=376, Percent_Identity=22.6063829787234, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1790572, Length=507, Percent_Identity=28.0078895463511, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786927, Length=489, Percent_Identity=29.4478527607362, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787922, Length=516, Percent_Identity=26.1627906976744, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1789911, Length=463, Percent_Identity=28.9416846652268, Blast_Score=192, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17569141, Length=409, Percent_Identity=23.4718826405868, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71987453, Length=404, Percent_Identity=23.5148514851485, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571098, Length=399, Percent_Identity=24.0601503759398, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28571102, Length=399, Percent_Identity=24.0601503759398, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571100, Length=399, Percent_Identity=24.0601503759398, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639583, Length=375, Percent_Identity=24, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639585, Length=377, Percent_Identity=23.8726790450928, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639581, Length=363, Percent_Identity=23.9669421487603, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56446; Mature: 56315

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKNIKNLDTSFFGHPKPLLSLSFTELWERFSFYGIRPLLVLFISAAIVYGGLGIERENA
CCCCCCCCHHHCCCCCHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCC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HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]