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The map label for this gene is cyoB [H]

Identifier: 153949620

GI number: 153949620

Start: 3490901

End: 3492892

Strand: Direct

Name: cyoB [H]

Synonym: YpsIP31758_3099

Alternate gene names: 153949620

Gene position: 3490901-3492892 (Clockwise)

Preceding gene: 153950359

Following gene: 153950151

Centisome position: 73.91

GC content: 49.4

Gene sequence:

>1992_bases
ATGTTGGGAAAATTAACACTTGATGCGGTTCCATTAGGCGAACCAATCATAATGGTGACCGTTGCCGCAATTATTATTGG
AGGAGCGGCACTGGTCGCTGCTCTGACTTATTTCGGCAAGTGGAAATGGCTGTGGAGCGAATGGCTGACTTCGGTTGACC
ATAAAAAAATCGGTATCATGTACATTCTGGTTGCCATGGTCATGCTGTTGCGTGGTTTTGCTGATGCCATCATGATGCGT
AGTCAGCAAGCGCTTGCTTCTGCGGGCGAAGCGGGTTTCCTACCACCTCACCACTATGATCAGATCTTCACCGCGCACGG
CGTTATCATGATTTTCTTCATGGCGATGCCTTTCGTTGTCGGCTTGATGAATATAGTTGTACCGCTACAAATCGGTGCAC
GTGACGTTGCCTTCCCGTTCCTAAACTCTCTGAGCTTCTGGCTCTTTGCCGTTGGGGTGGTGTTAATTAACATCTCTCTG
GGAGTCGGTGAATTTGCTCAGACTGGCTGGCTAGCTTACCCACCACTATCCGGTATTGAATACAGTCCTGGTGTCGGGGT
TGACTACTGGATATGGAGCCTACAGATCTCCGGTCTGGGGACATTGCTAACGGGTGTGAACTTCTTTGCGACTATCCTGA
AGATGCGTGCACCTGGCATGTCGATGATGAAAATGCCGGTCTTCACTTGGGCGGCATTTTGTACCAACATCTTGATTATC
GTTTCTTTCCCAATCCTGACGGTTACCGTCGCATTACTGACGCTAGATCGTTACCTTGGCACCCATTTCTTTACCAATGA
TATGGGTGGCAACATGATGATGTACATCAACCTGATTTGGGCCTGGGGCCATCCGGAAGTGTACATTTTGGTGTTGCCGG
TATTCGGGGTCTTCTCCGAAGTTACCGCAACCTTCTCAAGAAAGCGCCTGTTTGGTTACACCTCTCTCGTATGGGCAACC
ATCGCGATTACCGTCCTGTCGTTTATTGTTTGGCTACACCACTTCTTTACTATGGGGTCCGGTGCCAACGTTAACGCCTT
CTTCGGTATTGCCACGATGATCATTTCCATCCCAACAGGGGTGAAAATTTTCAACTGGTTGTTCACTATGTACCAAGGCC
GTATTCAGATTAACTCCGCAATGCTGTGGACTATTGGCTTCATCGTGACCTTCTCTATCGGCGGGATGACCGGGGTTCTG
CTGGCCGTGCCGGGTGCAAACTTTGTCCTGCATAACAGCCTGTTCCTGATTGCGCACTTCCATAACGTCATTATCGGTGG
TGTAGTATTTGGGTGCTTTGCTGGCCTGACGTACTGGTGGCCTAAATCATTCGGCTTTATGCTGAATGAGAAATGGGGTA
TCCGTGCATTCTGGTTCTGGATTATTGGTTTCTTCGTTGCCTTTATGCCGCTGTACGTATTGGGCTTTATGGGAATGACC
CGTCGTTTGAGCCAAGACATCAACCCAGAATTCCATACGATGCTCATGGTAGCCGCTGGTGGTGCAGCACTGATTGCTTG
CGGTATCTTGTGTCAGGTTATCCAAGTATTCGTCAGTATCCGTGACCGCGAACAAAACCGCGATCTGACCGGTGACCCAT
GGGGTGCCCGTACGCTGGAATGGTCGACTTCTTCCCCTCCGCCGTTCTATAACTTCGCCGTCGTTCCTAACGTTGTTGAC
CGTGATGAGTTCTGGGACATGAAAGAGAAAGGCGAGGCCTATAAGCGCCCAGCGAAATACGAAGAAATCCACATGCCGAA
GAATACCGGTGCAGGTGTGATTATTGCTGGCTTCAGCTTGATTTTCGGCTTTGCTATGGTCTGGTATATCTGGTGGCTAG
CCATTATTGGCTTCGTTGGCATGATCGTTACCTGGATCGTGAAAAGCTTCGACGAGGATGTAGATTACTATGTGCCAGCG
GCTGAAGTGGAGCGCATCGAAAATCTTCATCATGAACAAATCAGCAAAGCAGGCGTGAATCATGTCAACTGA

Upstream 100 bases:

>100_bases
ATGCCAAAAAATGGCCATGACATGCCAAAAGGCATGGATATGAGCCAGGGCATGGAAATGGGCGAACACACTGCTCACGC
CGGAGCCGAGGAATAAAACG

Downstream 100 bases:

>100_bases
AACTCTGACTAACCACAACGTAGCCCATGCAGAGCATGGGCATCACGATGCGGGAGCGACGAAAGTATTCGGCTTCTGGG
TCTACCTGATGAGCGACTGT

Product: cytochrome O ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MLGKLTLDAVPLGEPIIMVTVAAIIIGGAALVAALTYFGKWKWLWSEWLTSVDHKKIGIMYILVAMVMLLRGFADAIMMR
SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVVGLMNIVVPLQIGARDVAFPFLNSLSFWLFAVGVVLINISL
GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQISGLGTLLTGVNFFATILKMRAPGMSMMKMPVFTWAAFCTNILII
VSFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSEVTATFSRKRLFGYTSLVWAT
IAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYQGRIQINSAMLWTIGFIVTFSIGGMTGVL
LAVPGANFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWWPKSFGFMLNEKWGIRAFWFWIIGFFVAFMPLYVLGFMGMT
RRLSQDINPEFHTMLMVAAGGAALIACGILCQVIQVFVSIRDREQNRDLTGDPWGARTLEWSTSSPPPFYNFAVVPNVVD
RDEFWDMKEKGEAYKRPAKYEEIHMPKNTGAGVIIAGFSLIFGFAMVWYIWWLAIIGFVGMIVTWIVKSFDEDVDYYVPA
AEVERIENLHHEQISKAGVNHVN

Sequences:

>Translated_663_residues
MLGKLTLDAVPLGEPIIMVTVAAIIIGGAALVAALTYFGKWKWLWSEWLTSVDHKKIGIMYILVAMVMLLRGFADAIMMR
SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVVGLMNIVVPLQIGARDVAFPFLNSLSFWLFAVGVVLINISL
GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQISGLGTLLTGVNFFATILKMRAPGMSMMKMPVFTWAAFCTNILII
VSFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSEVTATFSRKRLFGYTSLVWAT
IAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYQGRIQINSAMLWTIGFIVTFSIGGMTGVL
LAVPGANFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWWPKSFGFMLNEKWGIRAFWFWIIGFFVAFMPLYVLGFMGMT
RRLSQDINPEFHTMLMVAAGGAALIACGILCQVIQVFVSIRDREQNRDLTGDPWGARTLEWSTSSPPPFYNFAVVPNVVD
RDEFWDMKEKGEAYKRPAKYEEIHMPKNTGAGVIIAGFSLIFGFAMVWYIWWLAIIGFVGMIVTWIVKSFDEDVDYYVPA
AEVERIENLHHEQISKAGVNHVN
>Mature_663_residues
MLGKLTLDAVPLGEPIIMVTVAAIIIGGAALVAALTYFGKWKWLWSEWLTSVDHKKIGIMYILVAMVMLLRGFADAIMMR
SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVVGLMNIVVPLQIGARDVAFPFLNSLSFWLFAVGVVLINISL
GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQISGLGTLLTGVNFFATILKMRAPGMSMMKMPVFTWAAFCTNILII
VSFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSEVTATFSRKRLFGYTSLVWAT
IAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYQGRIQINSAMLWTIGFIVTFSIGGMTGVL
LAVPGANFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWWPKSFGFMLNEKWGIRAFWFWIIGFFVAFMPLYVLGFMGMT
RRLSQDINPEFHTMLMVAAGGAALIACGILCQVIQVFVSIRDREQNRDLTGDPWGARTLEWSTSSPPPFYNFAVVPNVVD
RDEFWDMKEKGEAYKRPAKYEEIHMPKNTGAGVIIAGFSLIFGFAMVWYIWWLAIIGFVGMIVTWIVKSFDEDVDYYVPA
AEVERIENLHHEQISKAGVNHVN

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=38.160469667319, Blast_Score=330, Evalue=2e-90,
Organism=Escherichia coli, GI1786634, Length=663, Percent_Identity=84.3137254901961, Blast_Score=1177, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=445, Percent_Identity=40.6741573033708, Blast_Score=327, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=41.5902140672783, Blast_Score=243, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=34.5238095238095, Blast_Score=136, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74118; Mature: 74118

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGKLTLDAVPLGEPIIMVTVAAIIIGGAALVAALTYFGKWKWLWSEWLTSVDHKKIGIM
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
YILVAMVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNIVVPLQIGARDVAFPFLNSLSFWLFAVGVVLINISLGVGEFAQTGWLAYPPLSGIE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECCCCCCCC
YSPGVGVDYWIWSLQISGLGTLLTGVNFFATILKMRAPGMSMMKMPVFTWAAFCTNILII
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VSFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEECCCCCEEEEEEHHHHHHHH
VTATFSRKRLFGYTSLVWATIAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYQGRIQINSAMLWTIGFIVTFSIGGMTGVLLAVPGANFVLHNSLFLIAHF
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCHHEEEEEECCCCEEHHCHHHHHHHH
HNVIIGGVVFGCFAGLTYWWPKSFGFMLNEKWGIRAFWFWIIGFFVAFMPLYVLGFMGMT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQDINPEFHTMLMVAAGGAALIACGILCQVIQVFVSIRDREQNRDLTGDPWGARTLE
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
WSTSSPPPFYNFAVVPNVVDRDEFWDMKEKGEAYKRPAKYEEIHMPKNTGAGVIIAGFSL
CCCCCCCCCEEEEECCCCCCCHHHCCCHHHCHHHCCCCCCHHEECCCCCCCCEEHHHHHH
IFGFAMVWYIWWLAIIGFVGMIVTWIVKSFDEDVDYYVPAAEVERIENLHHEQISKAGVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
HVN
CCC
>Mature Secondary Structure
MLGKLTLDAVPLGEPIIMVTVAAIIIGGAALVAALTYFGKWKWLWSEWLTSVDHKKIGIM
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
YILVAMVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNIVVPLQIGARDVAFPFLNSLSFWLFAVGVVLINISLGVGEFAQTGWLAYPPLSGIE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECCCCCCCC
YSPGVGVDYWIWSLQISGLGTLLTGVNFFATILKMRAPGMSMMKMPVFTWAAFCTNILII
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VSFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEECCCCCEEEEEEHHHHHHHH
VTATFSRKRLFGYTSLVWATIAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYQGRIQINSAMLWTIGFIVTFSIGGMTGVLLAVPGANFVLHNSLFLIAHF
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCHHEEEEEECCCCEEHHCHHHHHHHH
HNVIIGGVVFGCFAGLTYWWPKSFGFMLNEKWGIRAFWFWIIGFFVAFMPLYVLGFMGMT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQDINPEFHTMLMVAAGGAALIACGILCQVIQVFVSIRDREQNRDLTGDPWGARTLE
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
WSTSSPPPFYNFAVVPNVVDRDEFWDMKEKGEAYKRPAKYEEIHMPKNTGAGVIIAGFSL
CCCCCCCCCEEEEECCCCCCCHHHCCCHHHCHHHCCCCCCHHEECCCCCCCCEEHHHHHH
IFGFAMVWYIWWLAIIGFVGMIVTWIVKSFDEDVDYYVPAAEVERIENLHHEQISKAGVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
HVN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]