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The map label for this gene is tusC

Identifier: 153949491

GI number: 153949491

Start: 4401972

End: 4402337

Strand: Reverse

Name: tusC

Synonym: YpsIP31758_3923

Alternate gene names: 153949491

Gene position: 4402337-4401972 (Counterclockwise)

Preceding gene: 153949993

Following gene: 153949089

Centisome position: 93.2

GC content: 45.36

Gene sequence:

>366_bases
ATGGCAAGAAAACGCATCGCTTTTATTTTTACTCAAGGCCCCCATGGCAGCTCAGCTGGACGTGAAGGGTTGGATGCTTT
GCTGGCCACCTCTGCTTTGAGCGAAGATATCGGCGTATTCTTTATCTCAGATGGTGTTTTGCAACTTTTACCTCAGCAAC
AGCCAGAAAAAATTCTTGCCAGAAACTATATTGCTACTTTCGGTGTCTTACCTCTGTACGATGTCGAAAATTGTTATCTC
TGCGAACGCTCATTGCAACAGCGTGGGTTGAGTAAAATGGCTGACTGGATCCTCGATGTAACGGTATTATCCCCGGCAGA
TTTACGCCGTGAACTGGGCACTTATGATGTTGTGCTGACTTTTTAA

Upstream 100 bases:

>100_bases
TCAATTTGGCCGCTGCGAATCTGCAACCCGGTTTTACATTGAGTGGTCTAGGGGCGCTGGCAGAAGCTACGTTGACTTGT
GATCGCATGGTGCAATTTTA

Downstream 100 bases:

>100_bases
TGAGGTTTGGGTATTCATAATGCTGTATACCGTCAGTCATTCACCTTATCACTGCGATTTATCTGCGCTGTTGAGATTAG
CGACATCTGAGGATGATATT

Product: sulfur relay protein TusC

Products: NA

Alternate protein names: tRNA 2-thiouridine synthesizing protein C

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MARKRIAFIFTQGPHGSSAGREGLDALLATSALSEDIGVFFISDGVLQLLPQQQPEKILARNYIATFGVLPLYDVENCYL
CERSLQQRGLSKMADWILDVTVLSPADLRRELGTYDVVLTF

Sequences:

>Translated_121_residues
MARKRIAFIFTQGPHGSSAGREGLDALLATSALSEDIGVFFISDGVLQLLPQQQPEKILARNYIATFGVLPLYDVENCYL
CERSLQQRGLSKMADWILDVTVLSPADLRRELGTYDVVLTF
>Mature_120_residues
ARKRIAFIFTQGPHGSSAGREGLDALLATSALSEDIGVFFISDGVLQLLPQQQPEKILARNYIATFGVLPLYDVENCYLC
ERSLQQRGLSKMADWILDVTVLSPADLRRELGTYDVVLTF

Specific function: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions

COG id: COG2923

COG function: function code P; Uncharacterized protein involved in the oxidation of intracellular sulfur

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dsrF/tusC family

Homologues:

Organism=Escherichia coli, GI1789742, Length=118, Percent_Identity=59.3220338983051, Blast_Score=154, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TUSC_YERP3 (A7FNP3)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402871.1
- ProteinModelPortal:   A7FNP3
- SMR:   A7FNP3
- STRING:   A7FNP3
- GeneID:   5386070
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3923
- eggNOG:   COG2923
- HOGENOM:   HBG496129
- OMA:   FKVLPLY
- ProtClustDB:   PRK00211
- BioCyc:   YPSE349747:YPSIP31758_3923-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00389
- InterPro:   IPR003787
- InterPro:   IPR017462
- TIGRFAMs:   TIGR03010

Pfam domain/function: PF02635 DrsE

EC number: NA

Molecular weight: Translated: 13436; Mature: 13304

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKRIAFIFTQGPHGSSAGREGLDALLATSALSEDIGVFFISDGVLQLLPQQQPEKILA
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCHHHHHH
RNYIATFGVLPLYDVENCYLCERSLQQRGLSKMADWILDVTVLSPADLRRELGTYDVVLT
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECHHHHHHHCCCEEEEEE
F
C
>Mature Secondary Structure 
ARKRIAFIFTQGPHGSSAGREGLDALLATSALSEDIGVFFISDGVLQLLPQQQPEKILA
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCHHHHHH
RNYIATFGVLPLYDVENCYLCERSLQQRGLSKMADWILDVTVLSPADLRRELGTYDVVLT
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECHHHHHHHCCCEEEEEE
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA