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The map label for this gene is 153937349

Identifier: 153937349

GI number: 153937349

Start: 1903194

End: 1904381

Strand: Reverse

Name: 153937349

Synonym: CLC_1793

Alternate gene names: NA

Gene position: 1904381-1903194 (Counterclockwise)

Preceding gene: 153934892

Following gene: 153936196

Centisome position: 50.64

GC content: 29.8

Gene sequence:

>1188_bases
ATGGCATCAAGTTTAGCTATTATTATTCTATTGGGATTAATCGCAAATAAGCTCTTTGAAAAATTAAAACTGCCAGGTCT
TTTAGGAATGTTAATATTAGGTATTTTAATAGGACCTCATGGCTTAAACTGGTTAAGCAAAGATATTTTAAATGCTTCAG
CGGATCTTAGAAAAATTGCTTTAATTGTAATTTTATTAAGGGCAGGATTAGGTCTTAATAAAGAAGAATTAAAATTGGTT
GGTAAAACAGCTCTAAAATTAAGCTGTATACCTGGAATTATAGAAGGATTATTCATAGCAATAGCCTCCGTAAAACTTTT
AGGTTTTTCTTTTGTACAAGGAGGCTTATTAGGATTTATTATTGCTGCAGTTTCACCAGCAGTAGTTGTACCTCAAATGT
TAAACTTAATAGACAAAGGCCTTGGGAAAGCTAAGGGTATACCAACTCTTATATTAGCCGGTGCTTCTATAGATGATGTT
TTTGCAATAACAATATTTAGCACATTTTTAGGATTATATGCGGGGAAGAATATAAATATAGCTATACAGATATTAAAAAT
ACCTGTTTCTATAATATTAGGTACATTAATTGGTGTATTATCAGCAATCATTATTATAAAGATATTTAAAAAGTATCCTA
TAGATAACACTAAAAAGATATTAATTATACTTAGTATATCTATTATACTTACTTTAATAGAAGCTTTACTAAAAGGTAAA
TTAGAAATAGCTAGCTTATTGGGTGTTATGGCTTTAGGATTTGTAATATCTGATAAAATTCCTAGTATAGGAGATAAAGT
ATCTAAAGGATTAAATGAAATATGGGTTTTTGCTCAAATACTTTTATTTGTTCTCGTAGGAGCTGAAGTAAATATGGTAA
TAGCTTTTAAATCAGGATTTTTAGGTATAATCATTATTGCTTTAGGTCTTATAGGAAGAAGTATAGGAGTATTAATTTCT
TTGAAAGGTTCAAATTTAAATAAAGAAGAAAAACTCTTTTGTATTATAGCCTATATCCCTAAAGCTACAGTTCAAGCAGC
TATGGGCGCAGTACCATTAGCCAATGGTGTAGCGGCAGGAGATATTATTTTAGCAATAGCAGTTTTGTCGATTTTAACTA
CAGCTCCATTGGGAGCTATAGCAATAAATTTATCTGGTCCAAGATTATTAGAATCAAACCTTTCTTAG

Upstream 100 bases:

>100_bases
GGAGTTCGCCATAATTGCGTAATGCTAATGACTCCTACAAATAATATAATTATTTGTAGGATTTTTTGCGTTTTGAGTAA
AATTTAAAGGAGGAAATTTT

Downstream 100 bases:

>100_bases
ACTAGATCAAATTTTTTATAAAATATATCTCTTTTGCTATAAAAAAATTTTGAAAAATACAAGAAAATCATTAAGTTGTA
TAAAAATAGATTTAATTTTA

Product: monovalent cation:proton antiporter-2 (CPA2) family protein

Products: NA

Alternate protein names: Na(+)/H(+) Antiporter; Transporter CPA2 Family; Na+/H+ Antiporter; Sodium/Proton Antiporter CPA1 Family; Na+/H+-Exchanging Protein; Sodium/Hydrogen Antiporter; Sodium/Hydrogen Exchanger Family Protein; Na+/H+-Exchanging ProteinNa+/H+ Antiporter; Monovalent CationProton Antiporter-2 Family Protein; Transporter Monovalent CationProton Antiporter-2 Family; Sodium/Hydrogen Exchanger/Universal Stress Family Protein

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MASSLAIIILLGLIANKLFEKLKLPGLLGMLILGILIGPHGLNWLSKDILNASADLRKIALIVILLRAGLGLNKEELKLV
GKTALKLSCIPGIIEGLFIAIASVKLLGFSFVQGGLLGFIIAAVSPAVVVPQMLNLIDKGLGKAKGIPTLILAGASIDDV
FAITIFSTFLGLYAGKNINIAIQILKIPVSIILGTLIGVLSAIIIIKIFKKYPIDNTKKILIILSISIILTLIEALLKGK
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGFLGIIIIALGLIGRSIGVLIS
LKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLANGVAAGDIILAIAVLSILTTAPLGAIAINLSGPRLLESNLS

Sequences:

>Translated_395_residues
MASSLAIIILLGLIANKLFEKLKLPGLLGMLILGILIGPHGLNWLSKDILNASADLRKIALIVILLRAGLGLNKEELKLV
GKTALKLSCIPGIIEGLFIAIASVKLLGFSFVQGGLLGFIIAAVSPAVVVPQMLNLIDKGLGKAKGIPTLILAGASIDDV
FAITIFSTFLGLYAGKNINIAIQILKIPVSIILGTLIGVLSAIIIIKIFKKYPIDNTKKILIILSISIILTLIEALLKGK
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGFLGIIIIALGLIGRSIGVLIS
LKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLANGVAAGDIILAIAVLSILTTAPLGAIAINLSGPRLLESNLS
>Mature_394_residues
ASSLAIIILLGLIANKLFEKLKLPGLLGMLILGILIGPHGLNWLSKDILNASADLRKIALIVILLRAGLGLNKEELKLVG
KTALKLSCIPGIIEGLFIAIASVKLLGFSFVQGGLLGFIIAAVSPAVVVPQMLNLIDKGLGKAKGIPTLILAGASIDDVF
AITIFSTFLGLYAGKNINIAIQILKIPVSIILGTLIGVLSAIIIIKIFKKYPIDNTKKILIILSISIILTLIEALLKGKL
EIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGFLGIIIIALGLIGRSIGVLISL
KGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLANGVAAGDIILAIAVLSILTTAPLGAIAINLSGPRLLESNLS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI47271479, Length=356, Percent_Identity=35.3932584269663, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI66793392, Length=358, Percent_Identity=33.2402234636872, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI154937338, Length=301, Percent_Identity=33.8870431893688, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17567635, Length=405, Percent_Identity=29.1358024691358, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI32566724, Length=409, Percent_Identity=30.0733496332518, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25152227, Length=420, Percent_Identity=26.4285714285714, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550940, Length=390, Percent_Identity=36.4102564102564, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129297, Length=390, Percent_Identity=36.4102564102564, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24649169, Length=400, Percent_Identity=31.75, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41268; Mature: 41137

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSLAIIILLGLIANKLFEKLKLPGLLGMLILGILIGPHGLNWLSKDILNASADLRKIA
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LIVILLRAGLGLNKEELKLVGKTALKLSCIPGIIEGLFIAIASVKLLGFSFVQGGLLGFI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAVSPAVVVPQMLNLIDKGLGKAKGIPTLILAGASIDDVFAITIFSTFLGLYAGKNINI
HHHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEE
AIQILKIPVSIILGTLIGVLSAIIIIKIFKKYPIDNTKKILIILSISIILTLIEALLKGK
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
LGIIIIALGLIGRSIGVLISLKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLANGVAAG
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCHHH
DIILAIAVLSILTTAPLGAIAINLSGPRLLESNLS
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCC
>Mature Secondary Structure 
ASSLAIIILLGLIANKLFEKLKLPGLLGMLILGILIGPHGLNWLSKDILNASADLRKIA
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LIVILLRAGLGLNKEELKLVGKTALKLSCIPGIIEGLFIAIASVKLLGFSFVQGGLLGFI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAVSPAVVVPQMLNLIDKGLGKAKGIPTLILAGASIDDVFAITIFSTFLGLYAGKNINI
HHHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEE
AIQILKIPVSIILGTLIGVLSAIIIIKIFKKYPIDNTKKILIILSISIILTLIEALLKGK
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
LGIIIIALGLIGRSIGVLISLKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLANGVAAG
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCHHH
DIILAIAVLSILTTAPLGAIAINLSGPRLLESNLS
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA