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The map label for this gene is yaeL [C]

Identifier: 153937005

GI number: 153937005

Start: 2403503

End: 2404513

Strand: Reverse

Name: yaeL [C]

Synonym: CLC_2272

Alternate gene names: 153937005

Gene position: 2404513-2403503 (Counterclockwise)

Preceding gene: 153936048

Following gene: 153934543

Centisome position: 63.94

GC content: 31.26

Gene sequence:

>1011_bases
ATGTATATAGTAGCGGCTATTTTAGCCTTTGGCATATTAGTTTTAGTCCATGAATTTGGTCATTTTATTATGGCTAAAGC
AAATGGTATAAAAGTTGAGGAGTTTTCTATAGGTATGGGGCCAAAGCTTATAGGAATAAAGGGCAAAGAGACAGAATATT
TAATAAAACTTTTACCAATAGGTGGCTATGTAAAAATGCTAGGAGACGAAGAAAAAAGTACAGATGAAAGAGCTTTTAAT
AACAAATCTCCTTTAAGAAAATTAAGTGTAGTGGTGGCAGGTCCTTTTATGAATTTAGTATTAAGTGTAGTTTTATTTGC
TATAATAGCGTCTCAAAGAGGATACTGGGCTCCTATAGTGGAAAAGGTAGTACCAAATGGACCTGCAGCAGTGGCAGGAT
TTATGCCAGGAGATAAAATAGTAAAGGTTAATGATAAAAAAATAACTACTTGGGATGATTTTGTTACAGTTATCTATTCA
GGAGATGGAGCACCTTTAAATATAAATTTCACACGAAATAATGTAGAGAACAATATCAAGTTAACTCCTATTAAAGATAC
TAAAGAAAATAGGTATATGATAGGTATATATCCTACACTAATAGAAAATATAAGTTTTAAAGAATCTGTAAAACAGGGAT
TTACACAAACAGGATCCTTAGTAAAACAAACTGTTGGATTTTTTAAAACCCTATTCCAAGGAAAGGTTTCTAAAAATGAT
GTAGGAGGACCACTAACTATAATTAAAGTTTCAGGAAAGGCAGCTAAGGCTGGTATAACGAGTTTAATGGCTTTTGCAGC
TTATATAAGCTTGCAACTGGCTATATTTAATATTATACCTTTCCCAGCCTTAGATGGAGGGTATATATTCTTATTTTTAT
TTGAAGCTATTACAGGAAAAAGAGTAGATGAAAATAAATTAGGTTTTGTAAATTATATAGGCTTTGTTATATTAATGGGG
CTTATGGTATTAGTAACCATAAAGGACATATTATACCCTATAAAATTTTAA

Upstream 100 bases:

>100_bases
TAATAAGTGTAGATAAGGAAGTTAGAGAGTATTTAGGTAAAAAATATGATATATAATAATAAAATTAATTTATAGGCACA
ATTTTAAGGGAGGTTAGTTA

Downstream 100 bases:

>100_bases
TATAATTAGAATCTAGAGAAATAGAAGTAATTTTTAAAGCAAATTTCATCGAAATTTAAGGATAACTTTATAAAAAACTT
TGCTTAACATTATAAATTCA

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MYIVAAILAFGILVLVHEFGHFIMAKANGIKVEEFSIGMGPKLIGIKGKETEYLIKLLPIGGYVKMLGDEEKSTDERAFN
NKSPLRKLSVVVAGPFMNLVLSVVLFAIIASQRGYWAPIVEKVVPNGPAAVAGFMPGDKIVKVNDKKITTWDDFVTVIYS
GDGAPLNINFTRNNVENNIKLTPIKDTKENRYMIGIYPTLIENISFKESVKQGFTQTGSLVKQTVGFFKTLFQGKVSKND
VGGPLTIIKVSGKAAKAGITSLMAFAAYISLQLAIFNIIPFPALDGGYIFLFLFEAITGKRVDENKLGFVNYIGFVILMG
LMVLVTIKDILYPIKF

Sequences:

>Translated_336_residues
MYIVAAILAFGILVLVHEFGHFIMAKANGIKVEEFSIGMGPKLIGIKGKETEYLIKLLPIGGYVKMLGDEEKSTDERAFN
NKSPLRKLSVVVAGPFMNLVLSVVLFAIIASQRGYWAPIVEKVVPNGPAAVAGFMPGDKIVKVNDKKITTWDDFVTVIYS
GDGAPLNINFTRNNVENNIKLTPIKDTKENRYMIGIYPTLIENISFKESVKQGFTQTGSLVKQTVGFFKTLFQGKVSKND
VGGPLTIIKVSGKAAKAGITSLMAFAAYISLQLAIFNIIPFPALDGGYIFLFLFEAITGKRVDENKLGFVNYIGFVILMG
LMVLVTIKDILYPIKF
>Mature_336_residues
MYIVAAILAFGILVLVHEFGHFIMAKANGIKVEEFSIGMGPKLIGIKGKETEYLIKLLPIGGYVKMLGDEEKSTDERAFN
NKSPLRKLSVVVAGPFMNLVLSVVLFAIIASQRGYWAPIVEKVVPNGPAAVAGFMPGDKIVKVNDKKITTWDDFVTVIYS
GDGAPLNINFTRNNVENNIKLTPIKDTKENRYMIGIYPTLIENISFKESVKQGFTQTGSLVKQTVGFFKTLFQGKVSKND
VGGPLTIIKVSGKAAKAGITSLMAFAAYISLQLAIFNIIPFPALDGGYIFLFLFEAITGKRVDENKLGFVNYIGFVILMG
LMVLVTIKDILYPIKF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=210, Percent_Identity=31.4285714285714, Blast_Score=104, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 36865; Mature: 36865

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIVAAILAFGILVLVHEFGHFIMAKANGIKVEEFSIGMGPKLIGIKGKETEYLIKLLPI
CHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCEEEEECCCCCEEEEEEECC
GGYVKMLGDEEKSTDERAFNNKSPLRKLSVVVAGPFMNLVLSVVLFAIIASQRGYWAPIV
CCEEEECCCCCCCCHHHHCCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHCCCCCCHHHH
EKVVPNGPAAVAGFMPGDKIVKVNDKKITTWDDFVTVIYSGDGAPLNINFTRNNVENNIK
HHHCCCCCCEEEECCCCCEEEEECCCEEEEHHHEEEEEECCCCCEEEEEEECCCCCCCEE
LTPIKDTKENRYMIGIYPTLIENISFKESVKQGFTQTGSLVKQTVGFFKTLFQGKVSKND
EEECCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VGGPLTIIKVSGKAAKAGITSLMAFAAYISLQLAIFNIIPFPALDGGYIFLFLFEAITGK
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
RVDENKLGFVNYIGFVILMGLMVLVTIKDILYPIKF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYIVAAILAFGILVLVHEFGHFIMAKANGIKVEEFSIGMGPKLIGIKGKETEYLIKLLPI
CHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCEEEEECCCCCEEEEEEECC
GGYVKMLGDEEKSTDERAFNNKSPLRKLSVVVAGPFMNLVLSVVLFAIIASQRGYWAPIV
CCEEEECCCCCCCCHHHHCCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHCCCCCCHHHH
EKVVPNGPAAVAGFMPGDKIVKVNDKKITTWDDFVTVIYSGDGAPLNINFTRNNVENNIK
HHHCCCCCCEEEECCCCCEEEEECCCEEEEHHHEEEEEECCCCCEEEEEEECCCCCCCEE
LTPIKDTKENRYMIGIYPTLIENISFKESVKQGFTQTGSLVKQTVGFFKTLFQGKVSKND
EEECCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VGGPLTIIKVSGKAAKAGITSLMAFAAYISLQLAIFNIIPFPALDGGYIFLFLFEAITGK
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
RVDENKLGFVNYIGFVILMGLMVLVTIKDILYPIKF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]