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The map label for this gene is ziaR [H]

Identifier: 153936771

GI number: 153936771

Start: 559425

End: 559613

Strand: Direct

Name: ziaR [H]

Synonym: CLC_0550

Alternate gene names: 153936771

Gene position: 559425-559613 (Clockwise)

Preceding gene: 153935648

Following gene: 153937186

Centisome position: 14.88

GC content: 30.69

Gene sequence:

>189_bases
ATGTGTGTATGTGATATTTCAAATCTTCTTAATATGACGCAATCAGCGGTGTCTCATCAACTCAAAGTTTTAAGAACAGC
TAGACTTATAAAATTTAGAAAAGAGGGTAAAGTTGTTTATTATTCATTAGATGACTCACATGTAGAGAATGTATTTAAGC
AAGGACTAGAACACATAATGCATAGATAA

Upstream 100 bases:

>100_bases
ATATGATAGAAGAAGATAAAGCGCAAGACTTAGGAGATTTTTTAAGGTTCTATCAGAACCGACTAGAATAAAAATTTTAT
ATGCATTATCATCATCAGAA

Downstream 100 bases:

>100_bases
AATTAAGTTTAATATTTTATTGTAATTTTAGAAATTTTGATTTTTTAATAACTATTTTAGAAGGATGGTGGGATCATGAT
TATAAAAAAGAAATTGCTTT

Product: putative cadmium resistance transcriptional regulator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 62; Mature: 62

Protein sequence:

>62_residues
MCVCDISNLLNMTQSAVSHQLKVLRTARLIKFRKEGKVVYYSLDDSHVENVFKQGLEHIMHR

Sequences:

>Translated_62_residues
MCVCDISNLLNMTQSAVSHQLKVLRTARLIKFRKEGKVVYYSLDDSHVENVFKQGLEHIMHR
>Mature_62_residues
MCVCDISNLLNMTQSAVSHQLKVLRTARLIKFRKEGKVVYYSLDDSHVENVFKQGLEHIMHR

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 7232; Mature: 7232

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVCDISNLLNMTQSAVSHQLKVLRTARLIKFRKEGKVVYYSLDDSHVENVFKQGLEHIM
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHH
HR
CC
>Mature Secondary Structure
MCVCDISNLLNMTQSAVSHQLKVLRTARLIKFRKEGKVVYYSLDDSHVENVFKQGLEHIM
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHH
HR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]