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The map label for this gene is hypD [H]

Identifier: 153936552

GI number: 153936552

Start: 1885168

End: 1886241

Strand: Reverse

Name: hypD [H]

Synonym: CLC_1776

Alternate gene names: 153936552

Gene position: 1886241-1885168 (Counterclockwise)

Preceding gene: 153935339

Following gene: 153935606

Centisome position: 50.16

GC content: 28.49

Gene sequence:

>1074_bases
ATGGCTAATTGCAAATTAATAATTGAAGTTATGGATAAGATAAAAGCTATAGATACAAGTCCTTTGAAGATAATGGAAGT
GTGTGGTAGCCATACTGAAGTTATAGGTAGATTAGGCTTGAGAGATATTTTATATCCTAAAGTAAATTTAGTATCTGGTC
CCGGTTGCCCTGTATGCGTAACAGATGAAAGCTATATAGATGCAGCCTTAAAGCTTTTAAATAGGGAAAATATATTAATA
ACCACTTTTGGTGATTTAATGAAAGTTAAAGGTACTACTAATAGTTTAATGGATGAAAAACCAAATCACAATAATATAAA
AGTTATATACTCGCCATTAGAGGCGCTTAAGATAGCAAAAGAAAATAAATCTTTAGAGGTTATTTTTCTAGCAGTTGGTT
TTGAAACTACTATCCCTTTAATAGCCTTATCTATAAAGCAAGCTAAAAATGAAAAGATAAAAAATATAAGTTTTCTACTA
GGTTTAAAAACAATGAAACCCATATTAGAACATATATTTAAAGATAAAAATCATAATATAGATGGGGTAATTTGTCCAGG
CCATGTAGCTTCTGTTAAGGGCGCTAATTATTTTAGATTTATAAGGGATGCATATAATATTCCTGCAGTAATATCAGGAT
TTGAACCCTTAGATATCTTAAGCTCTATATATTTTATTATAAATAGTAATATAAAAAATAAAAAAACTTTTATAAATTTA
TATAAAACCTGTGTAAAAGAAGATGGAAATAAAATTGCTAATGAGCTTATAGATGAGGTTTTTTGCCAAAATGATTCAAA
TTGGAGAGGTATAGGATTGATTAAAAACTCTGGATTAGATCTAAAAAATATATATAGTGACTATGATGCTTTAAAAAAAT
TCAATGTGAAAATTGAAAAGCATGAAAAATCCACTAGATGTATATGCGGTGAAGTTATATTAGGTAAAAAGTCTCCTAAA
GAATGTGACCTGTTTTCTAAAGAATGTAATCCAGGCCATTCAAAGGGCCCTTGTATGGTATCTAAAGAAGGGGCTTGTTC
TATATTTTATAGATACAATAAATTTAAGCTCTAA

Upstream 100 bases:

>100_bases
TATGTTCTAATTCATGCAGGTTGTGCTATAGAAAAAATAGACTATGAGTATTTTTCTTACTTAAAACAAATCATAAAAGA
AGCCTTAAGGAGTAATAAAG

Downstream 100 bases:

>100_bases
AGAATATTAAATTATAAACTAAAAGTGTAAAATACAAGACTTAAGCGGAAAGTACAAATTATTAATTAAATAACTGGCTT
TTAAACAAAAAGGTAAAATC

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MANCKLIIEVMDKIKAIDTSPLKIMEVCGSHTEVIGRLGLRDILYPKVNLVSGPGCPVCVTDESYIDAALKLLNRENILI
TTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAKENKSLEVIFLAVGFETTIPLIALSIKQAKNEKIKNISFLL
GLKTMKPILEHIFKDKNHNIDGVICPGHVASVKGANYFRFIRDAYNIPAVISGFEPLDILSSIYFIINSNIKNKKTFINL
YKTCVKEDGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYDALKKFNVKIEKHEKSTRCICGEVILGKKSPK
ECDLFSKECNPGHSKGPCMVSKEGACSIFYRYNKFKL

Sequences:

>Translated_357_residues
MANCKLIIEVMDKIKAIDTSPLKIMEVCGSHTEVIGRLGLRDILYPKVNLVSGPGCPVCVTDESYIDAALKLLNRENILI
TTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAKENKSLEVIFLAVGFETTIPLIALSIKQAKNEKIKNISFLL
GLKTMKPILEHIFKDKNHNIDGVICPGHVASVKGANYFRFIRDAYNIPAVISGFEPLDILSSIYFIINSNIKNKKTFINL
YKTCVKEDGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYDALKKFNVKIEKHEKSTRCICGEVILGKKSPK
ECDLFSKECNPGHSKGPCMVSKEGACSIFYRYNKFKL
>Mature_356_residues
ANCKLIIEVMDKIKAIDTSPLKIMEVCGSHTEVIGRLGLRDILYPKVNLVSGPGCPVCVTDESYIDAALKLLNRENILIT
TFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAKENKSLEVIFLAVGFETTIPLIALSIKQAKNEKIKNISFLLG
LKTMKPILEHIFKDKNHNIDGVICPGHVASVKGANYFRFIRDAYNIPAVISGFEPLDILSSIYFIINSNIKNKKTFINLY
KTCVKEDGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYDALKKFNVKIEKHEKSTRCICGEVILGKKSPKE
CDLFSKECNPGHSKGPCMVSKEGACSIFYRYNKFKL

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=335, Percent_Identity=38.8059701492537, Blast_Score=285, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 39976; Mature: 39845

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANCKLIIEVMDKIKAIDTSPLKIMEVCGSHTEVIGRLGLRDILYPKVNLVSGPGCPVCV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCHHHHHCCCEEEECCCCCCEEE
TDESYIDAALKLLNRENILITTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAK
CCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCHHHHCCCCCCCCEEEEECCHHHHHHHH
ENKSLEVIFLAVGFETTIPLIALSIKQAKNEKIKNISFLLGLKTMKPILEHIFKDKNHNI
CCCCEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGVICPGHVASVKGANYFRFIRDAYNIPAVISGFEPLDILSSIYFIINSNIKNKKTFINL
CEEECCCCHHHCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCCCHHHHHHH
YKTCVKEDGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYDALKKFNVKIEK
HHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEE
HEKSTRCICGEVILGKKSPKECDLFSKECNPGHSKGPCMVSKEGACSIFYRYNKFKL
CCCCCCEEECHHEECCCCCCCCCCHHCCCCCCCCCCCEEEECCCCEEEEEEECEECC
>Mature Secondary Structure 
ANCKLIIEVMDKIKAIDTSPLKIMEVCGSHTEVIGRLGLRDILYPKVNLVSGPGCPVCV
CCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCHHHHHCCCEEEECCCCCCEEE
TDESYIDAALKLLNRENILITTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAK
CCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCHHHHCCCCCCCCEEEEECCHHHHHHHH
ENKSLEVIFLAVGFETTIPLIALSIKQAKNEKIKNISFLLGLKTMKPILEHIFKDKNHNI
CCCCEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGVICPGHVASVKGANYFRFIRDAYNIPAVISGFEPLDILSSIYFIINSNIKNKKTFINL
CEEECCCCHHHCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCCCHHHHHHH
YKTCVKEDGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYDALKKFNVKIEK
HHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEE
HEKSTRCICGEVILGKKSPKECDLFSKECNPGHSKGPCMVSKEGACSIFYRYNKFKL
CCCCCCEEECHHEECCCCCCCCCCHHCCCCCCCCCCCEEEECCCCEEEEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]