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The map label for this gene is arcD [H]

Identifier: 153936488

GI number: 153936488

Start: 1689834

End: 1691252

Strand: Direct

Name: arcD [H]

Synonym: CLC_1618

Alternate gene names: 153936488

Gene position: 1689834-1691252 (Clockwise)

Preceding gene: 153935569

Following gene: 153935709

Centisome position: 44.94

GC content: 32.63

Gene sequence:

>1419_bases
ATGGGAACACAAGATAAAAAATTAGGTCTTGGACTTTTGATTACTCTCGGTATAGGCTCTATGATAGGCGGTGGGATTTT
TAATAGTCCCACGGACTTAATAACAAAAGCTAATCCACAAGCAGCTCTAATTGCTTGGATAATAGGTGGATTTGGAATTA
TATGCTTAGCACTAGTATTCCAATTTCTTGCTAATAAAAAACCAGATTTAAAAGGTGGAATTTATTCCTATTCACAGGAT
GGATTTGGAGACTTTATGGGTTTCAACTCAGCTTGGGGATATTGGCTTTCTGCTTGGCTTGGAAATATTGCTTTTATAGT
ATTAATGTTTAAAACCATAAACAGTTTATTAGGACCAGGACGTGAATTAAAGCCAATAGTGTCTTTTATAGCAGCATCTT
TATTATTATGGTCTGTACATTACATCCAAACAAAGGGAACAAAAAATGCAGGAATCATAAATGCAGTTGTAACTATAGGT
AAGTTATTACCGTTAACATTAGTTGTTATATTGGGTATATTCATATTTAAGCCAGAGCTATTTACAGTTTCAAACTGGAG
TACAATACTTGCAAGTTCTGGAAAAGCAACATCTACGTTTAAACAAGTTAATGGTGCCATGGGGACTATAATTTGGTGCT
TTATCGGTGTAGAAGCATCTGTAGTTCTTTCAGAAAAGGCAGAATCACAGGCTATAGTTGGAAAAGCAACAGTAATTAGT
TTGTTAATTACATTACTTATTTATGTTTCAATATCATTACTTGCAATGGGCATTATTCCAGCTAAGGATCTTGTAGTATC
AGGTACTCCTTTAGCAGATGTCTTATCAAAAACGGTCTTTGGAGGAGCAGGATCTGTAATAGTTAAATTAGGTCTTATAA
TATCATTGTTCGGAGCATTAATAAGTTGGGTAATGCTTGCAGCAGAGATACCATATGTAGCAGCTAAAGATGGAGTTATG
CCAAAATGGTTTGCTAAAGAGAACGCAGCAGGAGTTGCAATAAATTCATTAACATTTACAAATATTATAACTCAAGTATT
TTTATGTACATTACTTTCAGATAAATTACAATCAGCTTATAGTTTAGTATTTGCTATAGCAACTACTTGTATGTTAATTC
CTTATACTTTATCATCATTTTATGCTATAAAGGTATGTAATGAAGAAAAGATAAATGGAAAAGATAAGATAATAGCAATC
TTAGCTTCCATATATACAATATATGGTATATATGCAGGTGGAATTAAATACTTTGCTCTTGCATTTATAATGTACGCCTT
TGGAGTAATAGTTTTCAATAAAGCCAAGAAAGAAAAGAAACAAAAGTATACATCAATTGAGAAGATCGGTACAGCCGTAG
TTGTATTTGTAGGGGGAGTTATGATAGTTTTACTTTCAATAGGAAAAATATCACTATAA

Upstream 100 bases:

>100_bases
TAATTTATATAATTATGTTAACATAATCTATATAATTTTTCATGAAAATCTATATAATTTTGTATAATAATCTATATACA
TTGAGAAAAGAGGTTTGAAA

Downstream 100 bases:

>100_bases
TATTTAGATATAACTTGTGTAATATATTTTATATAAAGTAAAATATAAAAATTAAAACCGTCTCTATACTAAATAGGTTA
TTTATAAACTATGATTAAAA

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MGTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVFQFLANKKPDLKGGIYSYSQD
GFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPGRELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIG
KLLPLTLVVILGIFIFKPELFTVSNWSTILASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
LLITLLIYVSISLLAMGIIPAKDLVVSGTPLADVLSKTVFGGAGSVIVKLGLIISLFGALISWVMLAAEIPYVAAKDGVM
PKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAYSLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAI
LASIYTIYGIYAGGIKYFALAFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGGVMIVLLSIGKISL

Sequences:

>Translated_472_residues
MGTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVFQFLANKKPDLKGGIYSYSQD
GFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPGRELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIG
KLLPLTLVVILGIFIFKPELFTVSNWSTILASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
LLITLLIYVSISLLAMGIIPAKDLVVSGTPLADVLSKTVFGGAGSVIVKLGLIISLFGALISWVMLAAEIPYVAAKDGVM
PKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAYSLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAI
LASIYTIYGIYAGGIKYFALAFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGGVMIVLLSIGKISL
>Mature_471_residues
GTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVFQFLANKKPDLKGGIYSYSQDG
FGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPGRELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIGK
LLPLTLVVILGIFIFKPELFTVSNWSTILASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVISL
LITLLIYVSISLLAMGIIPAKDLVVSGTPLADVLSKTVFGGAGSVIVKLGLIISLFGALISWVMLAAEIPYVAAKDGVMP
KWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAYSLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAIL
ASIYTIYGIYAGGIKYFALAFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGGVMIVLLSIGKISL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=447, Percent_Identity=35.3467561521253, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI2367353, Length=455, Percent_Identity=25.7142857142857, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1786908, Length=418, Percent_Identity=23.9234449760766, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082250, Length=344, Percent_Identity=27.3255813953488, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790575, Length=465, Percent_Identity=21.7204301075269, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50353; Mature: 50222

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QFLANKKPDLKGGIYSYSQDGFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPG
HHHCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIGKLLPLTLVVILGIFIFKPEL
CHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FTVSNWSTILASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
EEECCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHH
LLITLLIYVSISLLAMGIIPAKDLVVSGTPLADVLSKTVFGGAGSVIVKLGLIISLFGAL
HHHHHHHHHHHHHHHHHCCCCHHHEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ISWVMLAAEIPYVAAKDGVMPKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAY
HHHHHHHHHCCCEECCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAILASIYTIYGIYAGGIKYFAL
HHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGGVMIVLLSIGKISL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GTQDKKLGLGLLITLGIGSMIGGGIFNSPTDLITKANPQAALIAWIIGGFGIICLALVF
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QFLANKKPDLKGGIYSYSQDGFGDFMGFNSAWGYWLSAWLGNIAFIVLMFKTINSLLGPG
HHHCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RELKPIVSFIAASLLLWSVHYIQTKGTKNAGIINAVVTIGKLLPLTLVVILGIFIFKPEL
CHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FTVSNWSTILASSGKATSTFKQVNGAMGTIIWCFIGVEASVVLSEKAESQAIVGKATVIS
EEECCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHH
LLITLLIYVSISLLAMGIIPAKDLVVSGTPLADVLSKTVFGGAGSVIVKLGLIISLFGAL
HHHHHHHHHHHHHHHHHCCCCHHHEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ISWVMLAAEIPYVAAKDGVMPKWFAKENAAGVAINSLTFTNIITQVFLCTLLSDKLQSAY
HHHHHHHHHCCCEECCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVFAIATTCMLIPYTLSSFYAIKVCNEEKINGKDKIIAILASIYTIYGIYAGGIKYFAL
HHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFIMYAFGVIVFNKAKKEKKQKYTSIEKIGTAVVVFVGGVMIVLLSIGKISL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9053381; 11792842 [H]