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The map label for this gene is hlyIII [C]

Identifier: 153936260

GI number: 153936260

Start: 1554253

End: 1554891

Strand: Reverse

Name: hlyIII [C]

Synonym: CLC_1488

Alternate gene names: 153936260

Gene position: 1554891-1554253 (Counterclockwise)

Preceding gene: 153937204

Following gene: 153935163

Centisome position: 41.35

GC content: 30.2

Gene sequence:

>639_bases
ATGTTAAATGAATTTTATACTAAAGGTGAAGAAATAGCAAATGCTATAACTCATGGTATTGGTGCTTTATTATCTATAGC
TGCCTTAGTTATTTTAATTGTATTTTCAGCTAAGTATGGAGATGCTTGGTATGTAACAAGTTACAGCATATTTGGATCAT
GCCTTTTTATATTATATTTGGAATCTACCTTATACCATAGTCTCCAGGGCAGCAAAGTAAAAAAAATATTTAGGATCTTT
GATCATTCCTCTATTTTTCTTTTAATTGCAGGTACCTATACCCCTTTTATACTTACCTCTCTTAGAGATCCTTTAGGTTG
GACTATATTTGGTATAGAATGGGGCCTTACTTTAATAGGAATCATTTTAAAAGTATTTACAACTGGTAAATACGAAAAAC
TATCCACTGCTATATATATTTTCATGGGTTGGCTTATAATGCTTCATGCTAAAAAATTAGTTTTAGTTATACCTAGAATA
TCCCTTATATATCTTATAGTAGGTGGAGTTATTTATACTGTTGGAGCCTTTCTTTTTATGTTAGATGATATACCTTACAA
CCACCCAATATGGCATTTATTTGTAATAGGTGGAAGTGTTTTTCACTTTTTCTCACTTTTCTATATGATACCTAGATAA

Upstream 100 bases:

>100_bases
TCACTATTGGTTAGCAATGGTGATTTTTTATTAATGTATAGTACATACTTTTACCATTATAGTATAATATAATATATATT
CTTAAAAAGGAGATATGTTT

Downstream 100 bases:

>100_bases
AGCTAAATATAATAAAAAACACTGTGAACTATATATCTAATAGATTTTCATAGTGTTTATTTTAATTGTAAAACTACAAA
AATTACCTATAACAAATTAA

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MLNEFYTKGEEIANAITHGIGALLSIAALVILIVFSAKYGDAWYVTSYSIFGSCLFILYLESTLYHSLQGSKVKKIFRIF
DHSSIFLLIAGTYTPFILTSLRDPLGWTIFGIEWGLTLIGIILKVFTTGKYEKLSTAIYIFMGWLIMLHAKKLVLVIPRI
SLIYLIVGGVIYTVGAFLFMLDDIPYNHPIWHLFVIGGSVFHFFSLFYMIPR

Sequences:

>Translated_212_residues
MLNEFYTKGEEIANAITHGIGALLSIAALVILIVFSAKYGDAWYVTSYSIFGSCLFILYLESTLYHSLQGSKVKKIFRIF
DHSSIFLLIAGTYTPFILTSLRDPLGWTIFGIEWGLTLIGIILKVFTTGKYEKLSTAIYIFMGWLIMLHAKKLVLVIPRI
SLIYLIVGGVIYTVGAFLFMLDDIPYNHPIWHLFVIGGSVFHFFSLFYMIPR
>Mature_212_residues
MLNEFYTKGEEIANAITHGIGALLSIAALVILIVFSAKYGDAWYVTSYSIFGSCLFILYLESTLYHSLQGSKVKKIFRIF
DHSSIFLLIAGTYTPFILTSLRDPLGWTIFGIEWGLTLIGIILKVFTTGKYEKLSTAIYIFMGWLIMLHAKKLVLVIPRI
SLIYLIVGGVIYTVGAFLFMLDDIPYNHPIWHLFVIGGSVFHFFSLFYMIPR

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=208, Percent_Identity=29.3269230769231, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI52630445, Length=213, Percent_Identity=27.6995305164319, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789266, Length=213, Percent_Identity=39.906103286385, Blast_Score=166, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71996356, Length=218, Percent_Identity=29.8165137614679, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 24044; Mature: 24044

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEFYTKGEEIANAITHGIGALLSIAALVILIVFSAKYGDAWYVTSYSIFGSCLFILYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHH
ESTLYHSLQGSKVKKIFRIFDHSSIFLLIAGTYTPFILTSLRDPLGWTIFGIEWGLTLIG
HHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEHHHHHHHHHH
IILKVFTTGKYEKLSTAIYIFMGWLIMLHAKKLVLVIPRISLIYLIVGGVIYTVGAFLFM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDIPYNHPIWHLFVIGGSVFHFFSLFYMIPR
HHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNEFYTKGEEIANAITHGIGALLSIAALVILIVFSAKYGDAWYVTSYSIFGSCLFILYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHH
ESTLYHSLQGSKVKKIFRIFDHSSIFLLIAGTYTPFILTSLRDPLGWTIFGIEWGLTLIG
HHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEHHHHHHHHHH
IILKVFTTGKYEKLSTAIYIFMGWLIMLHAKKLVLVIPRISLIYLIVGGVIYTVGAFLFM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDIPYNHPIWHLFVIGGSVFHFFSLFYMIPR
HHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]