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The map label for this gene is mcpB [H]

Identifier: 153936136

GI number: 153936136

Start: 2446154

End: 2448172

Strand: Reverse

Name: mcpB [H]

Synonym: CLC_2317

Alternate gene names: 153936136

Gene position: 2448172-2446154 (Counterclockwise)

Preceding gene: 153937306

Following gene: 153937628

Centisome position: 65.1

GC content: 28.88

Gene sequence:

>2019_bases
TTGAAAAAACTGTCCTTTAAAATGAAATTATTAATTACGATTTTACCAGTTGTAATAATTGGAATGTCAATTTTGAGTTT
TACAACATTTTATGAATTTAGAAAAAATATTGAAAATGAACTTATAAATAATAAATTGAAGGAAGGGAAAAAATTAACTG
AGAGTATAAACAATTGGTTAGAAGGAAAGCTTTTAGAAGTAAGAAGTTCTGCTAATACACCTACGGCAAAACTAATAGAA
ACAGATGTTTCTGCTGTAGATAATTTTAATGCAGAAAGAATTAAATTTTTAGAAAAAAATTATCCAGGAGAATATGACAA
TGCAGCAGCAACTTTATTTAATAATGATGGTAAATCTAGAGCTCAATATTCAAATGGAAAGTTTGTAAATGGCGATGTAT
CAGAAAAAACATGGTACAAGGATTTAATGAGTGGGGTACCATATAATATATCTAATCCTGTAGTATCAAAGGGAACTGGT
AAAACTTTGGTTGTAATAGGAGTTCCAATTAAAAACAAATCAGAAAAGACAATAGGAACAATGATATCTGCTGTGAATCT
TTTACATATTAAAGAAAAAGTTAAGGAATTTAAATTTGGTGAAAAAGGATATAGTTTATTAATTGGAAAGGATGGAACTA
TTCTTGAACATCCAGATAAGTCATTAGTAATGCAAAAAAAGATATCAGAAATAAAAGATGAAAATATACAATCATTAGGA
AAAGAAATGATGGAAAATAAATCAGGTGTATTTAGATTTGGAAGTGGAGATAATAAATCGATTGTATTTTATAATAAAGT
TCCTCTATCGGGGTGGAATGTAGCAAGTGTTGTGTCTGAAAAGGAATTGTTCGCTCCTTTAAATAAATTAATGTTAACAT
TAATTTTAATAACAATAGTAATTGTATTGATTGTTGCAACAGTAATTGTACTTGTAGCAAAACAAATCACATTACCATTA
ACTAAGTTATCTGATTTTGCAGAAGAAATAGCAGAAGGAAATCTTACAAATAAATTAGAAGTTCATGGGCAAGACGAAAT
TTCTAAGGTGACAAAAGCACTAAATAATACAGTTTTAAAGCTTAAAAAAATGATAGGTGATATAAGTAGTTCGGCTAATG
ATGTTATGGTAATATCTAATGGTTTAGCATCATCAACAAGTGAATCATTAAAGGGAAATGAAGAAGTTTCACGAAGTATG
CAAGAAATAGCCACAGGGGCTGTATCTCAGGCAGAAGGGGCAAGCAAAGCATCTATTGTAACAAGAGAATTAGTTGAAGA
TATAAATGAAATATCTAAAAAATGTAATTATATGATTAACATAGTGGAAAAATCAACTAATAGAAGCACAAAAGTTTCAC
AAGGAGTCCAACAAACTGTAGATAGTATAAAGAACATAGCTACAACAAATAAACATAATGTTGAAGAAATTCAAAATTTA
TTAAATCAATCTAAAGAAATAGGACAAATTGTTGATGTAATAAGTGATATATCTGAACAAACTAATCTTTTATCACTTAA
TGCAGCTATTGAAGCTGCTAGGGCTGGTGCACAAGGTAGAGGATTTGCTGTAGTCGCAGATGAGGTGAGGAAATTAGCAG
AACAGTCAAGTAATTCTTCAAAAAGGATAGTAGAGCTTATTAATCGAATTCAAAAACAAATTGAAATCATATCAAATAAA
ATGAATTCTGGAACAAGTGAAGTTATGCATGGAGTTAAAATGGCAACATTAATTGGTAATGATTTTGAAGAAATAGAGAA
AGTATTTAATGAAGTTAATAATATTGTATCAGAGGTATCAGAGTCTACTAATACGATGGAAAAGAAAGTAAATACTACAG
CTGATATTATAAATAATGTTGCAGCTGTAACAGAAGAGAATTCAGCAGCTACAGAAGAAGTCACTGCATCAAATGAAGAG
CAGATTGCTTTTATGCATCAAATTGTAGACTCAACTTATACATTAGAAGAATTAGTTAAAAAACTTAAGGATACAGTATA
TAAATTTAAATTATCCTAG

Upstream 100 bases:

>100_bases
TATTAAAAATAATTAATTTATATAAATATGTTTGTTAATTTTAGATAAGTTTTATGAAAATGTATATCTTACAAATGGAA
TTACGGGAGTGATGAAAATA

Downstream 100 bases:

>100_bases
ATAGAATTAAAAGTAATTTATATAGAAAGCTTATAATCTTACAAAATAAAGATTATAAGCTTTTTTTATTAAATCTTTTA
GAAATATCTACAAAAATAGA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWLEGKLLEVRSSANTPTAKLIE
TDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTG
KTLVVIGVPIKNKSEKTIGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQSLG
KEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIVIVLIVATVIVLVAKQITLPL
TKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVSRSM
QEIATGAVSQAEGASKASIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEIQNL
LNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSSKRIVELINRIQKQIEIISNK
MNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTASNEE
QIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS

Sequences:

>Translated_672_residues
MKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWLEGKLLEVRSSANTPTAKLIE
TDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTG
KTLVVIGVPIKNKSEKTIGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQSLG
KEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIVIVLIVATVIVLVAKQITLPL
TKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVSRSM
QEIATGAVSQAEGASKASIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEIQNL
LNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSSKRIVELINRIQKQIEIISNK
MNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTASNEE
QIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS
>Mature_672_residues
MKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWLEGKLLEVRSSANTPTAKLIE
TDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTG
KTLVVIGVPIKNKSEKTIGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQSLG
KEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIVIVLIVATVIVLVAKQITLPL
TKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVSRSM
QEIATGAVSQAEGASKASIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEIQNL
LNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSSKRIVELINRIQKQIEIISNK
MNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTASNEE
QIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=354, Percent_Identity=28.5310734463277, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI2367378, Length=350, Percent_Identity=26.5714285714286, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787690, Length=373, Percent_Identity=26.8096514745308, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788195, Length=325, Percent_Identity=26.7692307692308, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789453, Length=372, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 74015; Mature: 74015

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGKLLEVRSSANTPTAKLIETDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSR
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCH
AQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTGKTLVVIGVPIKNKSEKTIGT
HHCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
MISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQSLG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
KEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIV
HHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLIVATVIVLVAKQITLPLTKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHH
LKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVSRSMQEIATGAVSQAEGASKASIV
HHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
TRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEIQNL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSS
HHHHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCH
KRIVELINRIQKQIEIISNKMNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTASNEEQIAFMHQIVDSTYTLEELVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHH
KLKDTVYKFKLS
HHHHHHHHHCCC
>Mature Secondary Structure
MKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGKLLEVRSSANTPTAKLIETDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSR
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCH
AQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTGKTLVVIGVPIKNKSEKTIGT
HHCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
MISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQSLG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
KEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIV
HHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLIVATVIVLVAKQITLPLTKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHH
LKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVSRSMQEIATGAVSQAEGASKASIV
HHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
TRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEIQNL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSS
HHHHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCH
KRIVELINRIQKQIEIISNKMNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTASNEEQIAFMHQIVDSTYTLEELVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHH
KLKDTVYKFKLS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]