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The map label for this gene is 153935888

Identifier: 153935888

GI number: 153935888

Start: 556574

End: 557122

Strand: Direct

Name: 153935888

Synonym: CLC_0548

Alternate gene names: NA

Gene position: 556574-557122 (Clockwise)

Preceding gene: 153934920

Following gene: 153935648

Centisome position: 14.8

GC content: 29.87

Gene sequence:

>549_bases
ATGAAGAAATTAGAAGAGAAAATATTATATGAAGGTAAATGGATAAGTTTTAAGAAAATAAGTTATTTAAATAATGAAGA
AAAGCTTTTAAAATGGGAAGCAGTAGAGAGAACCAATACGACTAAAGCAGTGGTTATTGTGGCAAAATTAGTTCCAACGG
AGCGATATGTATTTATAAAACAATATAGACCAGCTATAGATAATTATGTTATAGGATTTCCTGCTGGATTATTAGAACAA
GAAGATGTTGAAGCAGAGGCTAAAAGAGAATTAAAAGAAGAAACAGGCTATGTGGGTAGGGTTATAGACATAAGTCCAGA
GATAAGACCTAACCCAGCTTTATTAACAGATTATACTATATTAGTTCAAATGGAGATTGATGAAAATGATGAATTAAATA
AAAATCCTAAGCAAGAACTAGAACCTTCAGAAGATATAGAGGTTATGTTAATGTCTAAAGAAGAAAGTAGAGATTTTTTA
ATAGAACAAAAAAATAATGGCGTAGATGTGGGAGTAGGTCCTTGGTACATATTTGGATTTAAATTATAA

Upstream 100 bases:

>100_bases
ACCAATAAAGCTTATAGTAGATCCTGCGGTACCAGGAGAGGGTGGAAGTAAAATAAAAATAGAGTATAGCTAGTAGTAGA
TAATTTATGGAGGTAATTAG

Downstream 100 bases:

>100_bases
TTAACTATTTATTAAGTGAATATAGTTTAAAAAATAAGGTGTTTCAAAATAGATTTTATTATGAAACATCTTATTTTTTT
GATTCATCAAGTGAGTAAAA

Product: NUDIX family hydrolase

Products: AMP; D-ribose 5-phosphate

Alternate protein names: MutT/Nudix Family Protein; Hydrolase; MutT/NUDIX Family Hydrolase; Hydrolase NUDIX Family

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKKLEEKILYEGKWISFKKISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIKQYRPAIDNYVIGFPAGLLEQ
EDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTILVQMEIDENDELNKNPKQELEPSEDIEVMLMSKEESRDFL
IEQKNNGVDVGVGPWYIFGFKL

Sequences:

>Translated_182_residues
MKKLEEKILYEGKWISFKKISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIKQYRPAIDNYVIGFPAGLLEQ
EDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTILVQMEIDENDELNKNPKQELEPSEDIEVMLMSKEESRDFL
IEQKNNGVDVGVGPWYIFGFKL
>Mature_182_residues
MKKLEEKILYEGKWISFKKISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIKQYRPAIDNYVIGFPAGLLEQ
EDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTILVQMEIDENDELNKNPKQELEPSEDIEVMLMSKEESRDFL
IEQKNNGVDVGVGPWYIFGFKL

Specific function: Unknown

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI37594464, Length=190, Percent_Identity=33.6842105263158, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17564994, Length=157, Percent_Identity=31.8471337579618, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319587, Length=166, Percent_Identity=30.7228915662651, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.13

Molecular weight: Translated: 21160; Mature: 21160

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLEEKILYEGKWISFKKISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIK
CCCHHHHHHCCCCCEEEEEEEECCCHHHEEEEEECCCCCCCEEEEEEEEECCCCEEEEEE
QYRPAIDNYVIGFPAGLLEQEDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTI
ECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEE
LVQMEIDENDELNKNPKQELEPSEDIEVMLMSKEESRDFLIEQKNNGVDVGVGPWYIFGF
EEEEEECCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCEEEEEE
KL
EC
>Mature Secondary Structure
MKKLEEKILYEGKWISFKKISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIK
CCCHHHHHHCCCCCEEEEEEEECCCHHHEEEEEECCCCCCCEEEEEEEEECCCCEEEEEE
QYRPAIDNYVIGFPAGLLEQEDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTI
ECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEE
LVQMEIDENDELNKNPKQELEPSEDIEVMLMSKEESRDFLIEQKNNGVDVGVGPWYIFGF
EEEEEECCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCEEEEEE
KL
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADPribose; H2O

Specific reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA