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The map label for this gene is opuCB [H]

Identifier: 153935827

GI number: 153935827

Start: 1747498

End: 1749081

Strand: Direct

Name: opuCB [H]

Synonym: CLC_1663

Alternate gene names: 153935827

Gene position: 1747498-1749081 (Clockwise)

Preceding gene: 153935704

Following gene: 153936037

Centisome position: 46.47

GC content: 28.91

Gene sequence:

>1584_bases
ATGAATAATTTTATACAGCAATTAATACTTAAAAGATCAGAAATATTCTCTCTTTTAATAGAACATATAGAACTTACTTT
AATAGCAGTTTTAATAGCAGTAGTTATTGGAGTGCCCCTTGGCATAATTATTACTAAAAATAAAAAGATAGCTAATATAG
TAATAGGTTTTGCAAATTTAACACAAGCTATACCAAGCTTAGCTATTTTAGGCTTTTTAATACCTTTAATAGGTATAGGA
TCAGCACCTGCTATAACTATGGTTGTTTTATATTCTATGCTACCAATATTAAAAAATACTTATACAGGAATTACTAATAT
AAATCCAGATATGCTAGAAGCAGCTAAAGGTTTAGGAATGACAAATACTCAAACTCTTAAATTAATAAAAATACCTTTAG
CAATGCCAATAATAATGGCAGGTGTAAGAATAGCATCAGTAACAGCCGTTGGACTTATGACTATAGCAGCCTTTGTAGGA
GCAGGTGGACTTGGATACTTAGTATTCTCAGGAATACAAACAGTAGATAATAATCTTATATTATTTGGTGCTATTCCAGC
TGCTATATTAGCTTTAATAATAGATTGGATAACAGGAAGAATAGAAGAGGCAACTATGCCAAATGGTATAAAAAAAGCAG
ATGGTACAATGAAAGTAAAAGGAAATTCTTCAAATAAAAACAGGAAAAGAAATACTATAATAGCATCAATATTAGGAGTT
CTTATAGTGTTAGCATTAATAGTTCCAAAGCTAATAGGACTAGGGGATAAAAAAGTAGTTATTGGTTCCAAAAACTTTAC
AGAACAGATTATCTTAGGTAACATATTGGAAGAGTTAATTGATAATAAAACAGATATAGATGTTGAAACAAAGTTAAATT
TAGGAGGAACTCAAGTAAGCTTTAATGCACTAAAAACTGGCGGAATAGATATGTATGTTGAATATACAGGTACTGCATAT
GGAAATATGCTAAATATAAAAAAACCTAATAGAGATAGACAGGCGGTTTATAATACAGTCAAAAAGGAGTTTAAGGAAAA
GTTTGGAATTGAAGTCTTAAACCCTATAGGTTTTAACAATACTTATGTAATGGCAACTACAAAAGAAATTGCACAAAAAT
ATAATTTAAAAACCACATCAGATTTAGCAAATGTATCAAGTAAAATGATATTAGGACCAACAATAGAATTTGCAAATAGA
GAAGATGGGATTATAGGTCTTAATAAAGCATATAATATGAATTTTAAGGCTGTTAAACCAATAGATGGTGGATTAAGGTA
TAAAGCTTTAGTTAATAATGAAACTCAAATTATAGATGCTTTTACAACAGATGGATTAATAGAGCAGTTTAATTTAGTTC
TTTTAGAGGATGACAAGCATTTTTTCCCAGATTATTATGCAGTTCCAATTGTAAAAGAAGAAACATTAAAGAAGTTCCCA
GAACTTAAAGAAGTTTTAGGAGCACTAGATGGAAAGATTACGGATGAAAAAATGAGAAAATTAAATTATGAAGTAGATGT
AAATAAAAGAGATCCTAAAGAAGTAGCAAAAGAATTTTTGCAAAAAGAAGGGTTAATAGATTAA

Upstream 100 bases:

>100_bases
CCTGTAAGTGATAGTGAAGGAAAACTTTTAGGGTTAATAACAAGAAGTAGTTTAATATCAGTTTTAAGTAGTCAATATAT
AGATATGGAGGGGATAATTG

Downstream 100 bases:

>100_bases
AATTATATACTAAAAATTATGTAAAGAGTTTAATTCTACATAATAAACTTAATACAGCATATTATTTAAAGCTTAATTAA
AGATCAGAAAATTTATTTTA

Product: glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANLTQAIPSLAILGFLIPLIGIG
SAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFVG
AGGLGYLVFSGIQTVDNNLILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILGV
LIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVSFNALKTGGIDMYVEYTGTAY
GNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNNTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFANR
EDGIIGLNKAYNMNFKAVKPIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKFP
ELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID

Sequences:

>Translated_527_residues
MNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANLTQAIPSLAILGFLIPLIGIG
SAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFVG
AGGLGYLVFSGIQTVDNNLILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILGV
LIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVSFNALKTGGIDMYVEYTGTAY
GNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNNTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFANR
EDGIIGLNKAYNMNFKAVKPIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKFP
ELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID
>Mature_527_residues
MNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANLTQAIPSLAILGFLIPLIGIG
SAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFVG
AGGLGYLVFSGIQTVDNNLILFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILGV
LIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVSFNALKTGGIDMYVEYTGTAY
GNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNNTYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFANR
EDGIIGLNKAYNMNFKAVKPIDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKFP
ELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=201, Percent_Identity=36.318407960199, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788449, Length=198, Percent_Identity=33.8383838383838, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788452, Length=301, Percent_Identity=27.5747508305648, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789033, Length=180, Percent_Identity=32.2222222222222, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786564, Length=170, Percent_Identity=27.0588235294118, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57658; Mature: 57658

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHEEEHHHH
TQAIPSLAILGFLIPLIGIGSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFVGAGGLGYLVFSGIQTVDNNLI
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
LFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILGV
EEECHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVS
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEE
FNALKTGGIDMYVEYTGTAYGNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNN
EEEEECCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCC
TYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFANREDGIIGLNKAYNMNFKAVKP
EEEEEEHHHHHHHCCCCCHHHHHHCCCCEEECCCEEECCCCCCEEECCCCCCCCCEEECC
IDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKFP
CCCCCEEEEEECCCCEEEEEHHCCCHHHHCCEEEEECCCCCCCCEEEECEECHHHHHHCH
ELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID
HHHHHHHHHCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNFIQQLILKRSEIFSLLIEHIELTLIAVLIAVVIGVPLGIIITKNKKIANIVIGFANL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHEEEHHHH
TQAIPSLAILGFLIPLIGIGSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TNTQTLKLIKIPLAMPIIMAGVRIASVTAVGLMTIAAFVGAGGLGYLVFSGIQTVDNNLI
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
LFGAIPAAILALIIDWITGRIEEATMPNGIKKADGTMKVKGNSSNKNRKRNTIIASILGV
EEECHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LIVLALIVPKLIGLGDKKVVIGSKNFTEQIILGNILEELIDNKTDIDVETKLNLGGTQVS
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEE
FNALKTGGIDMYVEYTGTAYGNMLNIKKPNRDRQAVYNTVKKEFKEKFGIEVLNPIGFNN
EEEEECCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCC
TYVMATTKEIAQKYNLKTTSDLANVSSKMILGPTIEFANREDGIIGLNKAYNMNFKAVKP
EEEEEEHHHHHHHCCCCCHHHHHHCCCCEEECCCEEECCCCCCEEECCCCCCCCCEEECC
IDGGLRYKALVNNETQIIDAFTTDGLIEQFNLVLLEDDKHFFPDYYAVPIVKEETLKKFP
CCCCCEEEEEECCCCEEEEEHHCCCHHHHCCEEEEECCCCCCCCEEEECEECHHHHHHCH
ELKEVLGALDGKITDEKMRKLNYEVDVNKRDPKEVAKEFLQKEGLID
HHHHHHHHHCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]