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The map label for this gene is exp5 [H]

Identifier: 153935681

GI number: 153935681

Start: 1709775

End: 1711433

Strand: Direct

Name: exp5 [H]

Synonym: CLC_1633

Alternate gene names: 153935681

Gene position: 1709775-1711433 (Clockwise)

Preceding gene: 153936226

Following gene: 153935035

Centisome position: 45.47

GC content: 31.83

Gene sequence:

>1659_bases
ATGAAAAGGAATAAGCTAGTATCTTTTGATTTTTGGCAAAAATTTGGAAAGACACTATTAGTTGTTGTGGCAGTTATGCC
TGCAGCAGGACTTATGATTTGTATTGGTAAACTTATAGGAATGCAGGCTTCTATGGGATTAGTACAGTCTGTAGCAAGAG
TAGTAGAAGATATAGGATGGGCAATAATAGGAAATCTTCACATTTTATTTGCAGTAGCAATCGGTGGATCTTGGGCAAAA
GAGCGTGCTGGAGGATCTTTTGCAGGATTACTTACTTTTATTCTTACAAATAGAATAACAGGAGCTATTTTCGGAGTTAA
ACCAGATATGTTTTCTGATGAAGCAGCAAAAGTAACTTCAATGTTTGGAAGACAATTAGTAGTTAAAGATTATTTTACAA
CTATACTTGGAGCACCCGCATTAAATATGGGTGTATTTATAGGTATAATTTCAGGATTTCTAGGAGCGTACTTATATAAT
AAATATTATAATTTTAATAAATTACCAAAATCTTTGGCTTTCTTTAATGGAAAAAGATTTGTACCATTTGTAGTTATACT
AGGATCTGTAGTAACAGCAATAATTTTATCTATGATTTGGCCTTCTATTCAAGGTGCGTTAAATGCTTTTGGAAAATGGA
TAGCAACATCTAAGGATACTGCACCAATAGTAGCACCTTTCATTTTTGGATCATTGGAACGTATATTATTACCTTTTGGA
CTTCATCATATGTTAACAGTACCGCTAAATTATACTTCTCTTGGAGGAACTTATAAAATTTTAACAGGGCCAACTGCAGG
TACTATAGTTGCAGGTCAAGATCCATTATGGCTTGCTTGGGCAAATGATTTGATTAATTTAAAAGCAACCGGCAATATGA
CAGAATATAATAATTTGTTAGCAACTGTTATACCTGCGCGTTTTAAAGTAGGGCAGGTAATAACATCTTCAGCTTCATTA
TTAGGTGTAGCTTTTGCAATGTATAAAAATGTAGATAAAGATAAAAGAGATAAATATAAAACTGTTTTCTTATCAGCGGC
ATTAGCAGTATTTTTAACAGGTGTTACAGAACCTATAGAATTTATGTTTATGTTTATATCACCAATTTTATATGGAGTTT
ATGCAGTTATTACAGGAACAGCTTTTGCTTTAGCAGATTTAATAAACTTAAGAGTTCACTGTTTTGGATTCGTTGAATTT
ATAGCTCGTACTCCTATGATGATAAAGGCTGGAATTACAAGAGATATGTTAAACTTTGCAATTGTATCAGTTATATATTT
TGTATTAACTTATTTAATATTTAATTTTTTAATAAAGAAATTCAATATACCTACTCCAGGTAGAGCAGGAAACTATATTG
AAATGGAAGGAGAAGAAGATAAAAAAGAAGAAAAAATATCAGAAAAAGATATAGATAGAGATTCATTGTCAGTGAAAATA
ATAGGTTTACTAGGAGAAAAGGAAAATATAGTAGATGTAGATGCCTGCATGACTCGTCTTCGTGTAACAGTAAAGGATAA
AGGCTTAGTTGCAGAGGAAAAAGAGTGGAAAAAACTTGGAGCATTAGGTCTTATAGTAAAGGATAAAGGGGTTCAGGCTA
TATATGGACCAAAGGCAGATGTATTAAAATCAGATATTCAAGATATTTTAGGAGATTAA

Upstream 100 bases:

>100_bases
AGGATATAACAGAAATATTATTAAAGCCTTTTGAAGCGAGACTTTATAAAATAGTTTGAAATTTAAATTAATATAGATTA
TAAATATTGGGGGGATAAAA

Downstream 100 bases:

>100_bases
TTTATGAAGATTCTTACTTTGAATTGTCACTCTTGGCAAGAAGAAAAACAATTAGAAAAGATAAAATATTTAGCAAAGGT
GATATACGAAAATAATTATG

Product: PTS system, glucose/glucoside family, IIBC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKRNKLVSFDFWQKFGKTLLVVVAVMPAAGLMICIGKLIGMQASMGLVQSVARVVEDIGWAIIGNLHILFAVAIGGSWAK
ERAGGSFAGLLTFILTNRITGAIFGVKPDMFSDEAAKVTSMFGRQLVVKDYFTTILGAPALNMGVFIGIISGFLGAYLYN
KYYNFNKLPKSLAFFNGKRFVPFVVILGSVVTAIILSMIWPSIQGALNAFGKWIATSKDTAPIVAPFIFGSLERILLPFG
LHHMLTVPLNYTSLGGTYKILTGPTAGTIVAGQDPLWLAWANDLINLKATGNMTEYNNLLATVIPARFKVGQVITSSASL
LGVAFAMYKNVDKDKRDKYKTVFLSAALAVFLTGVTEPIEFMFMFISPILYGVYAVITGTAFALADLINLRVHCFGFVEF
IARTPMMIKAGITRDMLNFAIVSVIYFVLTYLIFNFLIKKFNIPTPGRAGNYIEMEGEEDKKEEKISEKDIDRDSLSVKI
IGLLGEKENIVDVDACMTRLRVTVKDKGLVAEEKEWKKLGALGLIVKDKGVQAIYGPKADVLKSDIQDILGD

Sequences:

>Translated_552_residues
MKRNKLVSFDFWQKFGKTLLVVVAVMPAAGLMICIGKLIGMQASMGLVQSVARVVEDIGWAIIGNLHILFAVAIGGSWAK
ERAGGSFAGLLTFILTNRITGAIFGVKPDMFSDEAAKVTSMFGRQLVVKDYFTTILGAPALNMGVFIGIISGFLGAYLYN
KYYNFNKLPKSLAFFNGKRFVPFVVILGSVVTAIILSMIWPSIQGALNAFGKWIATSKDTAPIVAPFIFGSLERILLPFG
LHHMLTVPLNYTSLGGTYKILTGPTAGTIVAGQDPLWLAWANDLINLKATGNMTEYNNLLATVIPARFKVGQVITSSASL
LGVAFAMYKNVDKDKRDKYKTVFLSAALAVFLTGVTEPIEFMFMFISPILYGVYAVITGTAFALADLINLRVHCFGFVEF
IARTPMMIKAGITRDMLNFAIVSVIYFVLTYLIFNFLIKKFNIPTPGRAGNYIEMEGEEDKKEEKISEKDIDRDSLSVKI
IGLLGEKENIVDVDACMTRLRVTVKDKGLVAEEKEWKKLGALGLIVKDKGVQAIYGPKADVLKSDIQDILGD
>Mature_552_residues
MKRNKLVSFDFWQKFGKTLLVVVAVMPAAGLMICIGKLIGMQASMGLVQSVARVVEDIGWAIIGNLHILFAVAIGGSWAK
ERAGGSFAGLLTFILTNRITGAIFGVKPDMFSDEAAKVTSMFGRQLVVKDYFTTILGAPALNMGVFIGIISGFLGAYLYN
KYYNFNKLPKSLAFFNGKRFVPFVVILGSVVTAIILSMIWPSIQGALNAFGKWIATSKDTAPIVAPFIFGSLERILLPFG
LHHMLTVPLNYTSLGGTYKILTGPTAGTIVAGQDPLWLAWANDLINLKATGNMTEYNNLLATVIPARFKVGQVITSSASL
LGVAFAMYKNVDKDKRDKYKTVFLSAALAVFLTGVTEPIEFMFMFISPILYGVYAVITGTAFALADLINLRVHCFGFVEF
IARTPMMIKAGITRDMLNFAIVSVIYFVLTYLIFNFLIKKFNIPTPGRAGNYIEMEGEEDKKEEKISEKDIDRDSLSVKI
IGLLGEKENIVDVDACMTRLRVTVKDKGLVAEEKEWKKLGALGLIVKDKGVQAIYGPKADVLKSDIQDILGD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=545, Percent_Identity=32.4770642201835, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1787908, Length=564, Percent_Identity=27.4822695035461, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1786894, Length=546, Percent_Identity=29.8534798534799, Blast_Score=188, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011300 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 60462; Mature: 60462

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916; 7934910 [H]