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The map label for this gene is yfmR [H]

Identifier: 153935518

GI number: 153935518

Start: 1144461

End: 1146380

Strand: Reverse

Name: yfmR [H]

Synonym: CLC_1116

Alternate gene names: 153935518

Gene position: 1146380-1144461 (Counterclockwise)

Preceding gene: 153934791

Following gene: 153936250

Centisome position: 30.48

GC content: 28.39

Gene sequence:

>1920_bases
ATGATTATAGTAACTGTTGAAAATATATGTAAAAGTTATGGTGAAAAAACTTTATTTAAAGATGTTTCTTTTACCATAAG
TGATGAATATAAAATAGGTTTAATAGGAGTTAACGGTACAGGAAAGTCTTCTCTTTTAAAAATTGTTACCGGTGAAGATA
GCCCTGATGGTGGTACCATTACTATTCCTAAGGGAGCTACCATTGAATATTTAGATCAAAATCCAGATTTAGATCCTAAT
GCTACAATATTAGAACAAGTATTTAAAGGTAATTCTAAAATAATGTCTGTAATAGGTGAATATGAAAAAGCTTTAGACCT
AATTTCTAAAAATCCTGAGGATGAAAAACTGCAAAATCATTTATTAACATTAACTAGTGAAATGGATTCCTTAGATGCCT
GGGATCTTGAAAGCAAAATTAAAACCGTTCTTACTAAACTTAATGTAACAGACTTTGATAAAAAAATAAAAGAGCTTTCT
GGTGGACAAAAGAAAAGAGTCGCCTTGTGCAGCGCTTTAATATCTCCTTGCGATTTGCTTGTATTAGATGAACCAACAAA
CCACATGGATAATGACACTATAGATTGGCTTGAAAATTATCTGCAAACTAGAAAAGGTGCCCTTTTAATGGTAACCCATG
ACAGATATTTTCTAGATAGAGTTGTTAATAAAACTTTAGAATTAGACTACGGAACTATGTACACTTACAATTGTAATTAT
TCACAATTTGTAGAAAAGAAAGCAGAAAGAAAAACATTAGAAAATTCCTTAGAAGAAAAAAGGCAAAGTCTTTATAAAAA
AGAATTAGAATGGATTAGAGCTGGCGTTCAAGCAAGAGGCACTAAACAAAAAGCAAGAATAAAAAGATTTGAAGAATTAG
GAGAAAGCAGTTTTAACCATAATAGTAATGATATAGATATATCTGTAGCTCATTCAAGATTAGGTAAAAAAATAATTAAT
ATAGAAAACCTAACTAAAAAATTTGAAGAAAAAACTTTAATAAAAGACTTTAATTACATTTTACTTAGGAATGATCGCAT
TGGTATAGTGGGAAACAATGGAATGGGTAAGTCTACCCTTTTAAATATTATTACAAATAAAATAAATTCAGATAGTGGTT
CTATTGATATAGGTACTACAGTAAATATTGCATATTTCTCGCAGCATTCAGAGGATATGGATCCAAATTTAAGAGCTATA
GAATATATAAGAGAAACAGCAGAATTTATAACCACAGCAGATGGAACTAAAATAAGTGCATCTCAAATGATGGAAAGATT
TCTTTTCACAGATGATATGCAATGGTGCTATATTTCAAAACTATCCGGTGGAGAAAAAAGAAGACTATATCTTTTAAAAA
TCTTAATGACTGCACCTAATGTACTTATATTGGATGAACCAACTAATGATCTAGATATTGATACATTAAAAGTTTTAGAA
AACTATATTGATGAATTTAATGGTCCAGTTATATCCGTATCCCATGATAGATACTTTTTAGATAGAACCTGTAATAAAAT
CCTTCACTTTGAAGGCAACGGAAAAATTTCTGAGTACATAGGAAACTATTCAGACTTTATATATAGGAAAAAAGAGATCT
CAAATATAACTTCAAAAGAAGAAAAAACAAATAAAGCTTTAAAAGAAAATAATAGTCAAAAGGAAAAAACATCAAAATTA
AAATTCTCTTATAAAGAAAAACTTGAATATGAAAATATAGATAAAGAAATAGAAAAACTAGAAGAAAAATTATCTAAACT
AGAAGAAGAAGTAGAAATAAATGCCTCTGACTTTATGAGACTTGAAGATCTTTTAAAGGAGAAGGATAAAGTTGAGGAAG
AACTATTATTTAAAATGGAAAGACAAGAATACTTAGAAAATCTAGCAAAAGAAATAGAGGAAAATAAAAAAACTGTGTAA

Upstream 100 bases:

>100_bases
ATACAATCTATTTTGCAATATTTATGTTTTACTATAAATGTTTTTTATAATAGAATATACATCATAGAGTATAAATTAAA
TTAACAAAAGGATGATTTTA

Downstream 100 bases:

>100_bases
GTAAGTTATGCTACCCGTGGTTTAAAAAACGGATATGTGCTTATAAAGGCAACTCACTTCAATAAGAGATTCTAATTTGT
TTTTTCTTAAAATATATGGC

Product: drug resistance ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MIIVTVENICKSYGEKTLFKDVSFTISDEYKIGLIGVNGTGKSSLLKIVTGEDSPDGGTITIPKGATIEYLDQNPDLDPN
ATILEQVFKGNSKIMSVIGEYEKALDLISKNPEDEKLQNHLLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELS
GGQKKRVALCSALISPCDLLVLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
SQFVEKKAERKTLENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELGESSFNHNSNDIDISVAHSRLGKKIIN
IENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTLLNIITNKINSDSGSIDIGTTVNIAYFSQHSEDMDPNLRAI
EYIRETAEFITTADGTKISASQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
NYIDEFNGPVISVSHDRYFLDRTCNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKEEKTNKALKENNSQKEKTSKL
KFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMRLEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV

Sequences:

>Translated_639_residues
MIIVTVENICKSYGEKTLFKDVSFTISDEYKIGLIGVNGTGKSSLLKIVTGEDSPDGGTITIPKGATIEYLDQNPDLDPN
ATILEQVFKGNSKIMSVIGEYEKALDLISKNPEDEKLQNHLLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELS
GGQKKRVALCSALISPCDLLVLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
SQFVEKKAERKTLENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELGESSFNHNSNDIDISVAHSRLGKKIIN
IENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTLLNIITNKINSDSGSIDIGTTVNIAYFSQHSEDMDPNLRAI
EYIRETAEFITTADGTKISASQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
NYIDEFNGPVISVSHDRYFLDRTCNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKEEKTNKALKENNSQKEKTSKL
KFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMRLEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV
>Mature_639_residues
MIIVTVENICKSYGEKTLFKDVSFTISDEYKIGLIGVNGTGKSSLLKIVTGEDSPDGGTITIPKGATIEYLDQNPDLDPN
ATILEQVFKGNSKIMSVIGEYEKALDLISKNPEDEKLQNHLLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELS
GGQKKRVALCSALISPCDLLVLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
SQFVEKKAERKTLENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELGESSFNHNSNDIDISVAHSRLGKKIIN
IENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTLLNIITNKINSDSGSIDIGTTVNIAYFSQHSEDMDPNLRAI
EYIRETAEFITTADGTKISASQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
NYIDEFNGPVISVSHDRYFLDRTCNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKEEKTNKALKENNSQKEKTSKL
KFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMRLEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=528, Percent_Identity=27.2727272727273, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI27881506, Length=519, Percent_Identity=28.7090558766859, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI10947137, Length=519, Percent_Identity=28.7090558766859, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI10947135, Length=557, Percent_Identity=26.9299820466786, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI69354671, Length=557, Percent_Identity=26.9299820466786, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI153792144, Length=195, Percent_Identity=31.7948717948718, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI2367384, Length=545, Percent_Identity=35.9633027522936, Blast_Score=355, Evalue=5e-99,
Organism=Escherichia coli, GI1787182, Length=636, Percent_Identity=32.5471698113208, Blast_Score=343, Evalue=3e-95,
Organism=Escherichia coli, GI1789751, Length=674, Percent_Identity=30.1186943620178, Blast_Score=291, Evalue=1e-79,
Organism=Escherichia coli, GI1787041, Length=538, Percent_Identity=29.5539033457249, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI48994943, Length=488, Percent_Identity=23.5655737704918, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1790525, Length=563, Percent_Identity=22.7353463587922, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788165, Length=222, Percent_Identity=26.1261261261261, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789891, Length=233, Percent_Identity=27.4678111587983, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786872, Length=252, Percent_Identity=25, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=557, Percent_Identity=29.443447037702, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17553372, Length=517, Percent_Identity=30.5609284332689, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17555318, Length=559, Percent_Identity=27.5491949910555, Blast_Score=181, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6320874, Length=543, Percent_Identity=29.6500920810313, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6321121, Length=559, Percent_Identity=27.7280858676207, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324314, Length=394, Percent_Identity=26.3959390862944, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=385, Percent_Identity=25.4545454545455, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6325030, Length=425, Percent_Identity=24.7058823529412, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24666836, Length=548, Percent_Identity=30.1094890510949, Blast_Score=219, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24641342, Length=562, Percent_Identity=28.2918149466192, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24642252, Length=564, Percent_Identity=28.0141843971631, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI18859989, Length=564, Percent_Identity=28.0141843971631, Blast_Score=189, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73477; Mature: 73477

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVTVENICKSYGEKTLFKDVSFTISDEYKIGLIGVNGTGKSSLLKIVTGEDSPDGGTI
CEEEEHHHHHHHHCCHHHHHCCEEEEECCEEEEEEEECCCCCCCEEEEEECCCCCCCCEE
TIPKGATIEYLDQNPDLDPNATILEQVFKGNSKIMSVIGEYEKALDLISKNPEDEKLQNH
EECCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELSGGQKKRVALCSALISPCDLL
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEE
VLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
EECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCH
SQFVEKKAERKTLENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELGESSFNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
NSNDIDISVAHSRLGKKIINIENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCHHHH
LNIITNKINSDSGSIDIGTTVNIAYFSQHSEDMDPNLRAIEYIRETAEFITTADGTKISA
HHHHHHHCCCCCCCEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECH
SQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
NYIDEFNGPVISVSHDRYFLDRTCNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKE
HHHHHHCCCEEEEECCCHHHHHHHHHHEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
EKTNKALKENNSQKEKTSKLKFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMR
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIVTVENICKSYGEKTLFKDVSFTISDEYKIGLIGVNGTGKSSLLKIVTGEDSPDGGTI
CEEEEHHHHHHHHCCHHHHHCCEEEEECCEEEEEEEECCCCCCCEEEEEECCCCCCCCEE
TIPKGATIEYLDQNPDLDPNATILEQVFKGNSKIMSVIGEYEKALDLISKNPEDEKLQNH
EECCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELSGGQKKRVALCSALISPCDLL
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEE
VLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
EECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCH
SQFVEKKAERKTLENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELGESSFNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
NSNDIDISVAHSRLGKKIINIENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCHHHH
LNIITNKINSDSGSIDIGTTVNIAYFSQHSEDMDPNLRAIEYIRETAEFITTADGTKISA
HHHHHHHCCCCCCCEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECH
SQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
NYIDEFNGPVISVSHDRYFLDRTCNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKE
HHHHHHCCCEEEEECCCHHHHHHHHHHEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
EKTNKALKENNSQKEKTSKLKFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMR
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]