Click here to switch to the map view.

The map label for this gene is hbpA [H]

Identifier: 153935301

GI number: 153935301

Start: 1789566

End: 1791161

Strand: Direct

Name: hbpA [H]

Synonym: CLC_1696

Alternate gene names: 153935301

Gene position: 1789566-1791161 (Clockwise)

Preceding gene: 153935862

Following gene: 153935101

Centisome position: 47.59

GC content: 28.76

Gene sequence:

>1596_bases
GTGAAAACGATATCAAAAAAGAGTATGTTGTTGGTATTTACAATGCTAATAGCTATAAGCTTTTTGTTTACAGGTTGTAA
AGGAGGTAAAAAAGAGGCAGAAGCTACCAATGCAAATAATAAATCAGAAAAAAAAGACGTAAATATTAAATTAGAAGGTG
GAGATTGGGGAGAACCAAATCCATATAAAACATATCCTAGAGGACCAGGAATGTCCAAGACCAATTTAATATATGATTCC
CTTATAGAAAAGGATGAAAAGAGAATTATACCATGGCTTGCAGAAAAATGGGAGGTAAAAAGCAATGGGAAGGAATATTT
ATTTAAAATAAGGGAAGGAGTAAAATGGCAAGATGGTAAGGACTTTACTCCAGAAGATGTTAAATTTACTTTTGATTATT
ATAAAAAACACCCACCAGTAAGCAAAAATATATACATAGGTAAAAAATGTTTTATAGATAAGGTAGAAGTATTAAAGGAT
AACTATATAAAAATAACAGTTAATACAGTAAATGCAGCTTCTTTAGAAAATCTAGGAACTACTAGAATAATACCAAAGCA
TATTTGGGAAAAGGTAGAGGATCCTAAAAAATTTGATGGCAAGGAAGCTTTTATAGGTTGTGGACCATACATGCTGGAGG
ATTATAATAAAGAAAGAGGTTCTTATAAATTTACTGCTTTTGAAGATTATTGGGGACCAAAACAAAATGTTAAAACTATA
GAGTTTATTCCAGTGAGTGATTCTATACTTGCCTTTGAAAAAGGTGATATAGATCTAGTAGGAAGTGTTAAACCAGATAT
AGCTAAAAAATATGAAAATAATAAAGAATATAAATTAATAAAAGGACATAACTTCTTTGGATATAGATTATGTTTAAATA
TGAATAAAAATCCAGAATTTAAGGACAAAAATGTAAGACAAGCTATAGCCTATGCTATAGATGAAAAAGAAATAATAGAT
AAAGTTATGAGAGGAATAGGAACAGAAGGAAGTGCAGCCTATTTGCCAAAGGAACATATATGGTATAACAAAGATATAAA
AAAATATGATTATAATGTAGAAAAGGCTAAAGAACTTTTAAAGGGTAAAAATATAACTTTCCAAATTATTGTATCTAATA
AAAAAGATAATTTAAGAATGGCAGAACTTTTAAAATTACAATTAGAAAAAACAGGAATGAAAGTTAATGTTAAAAGCATT
GATATGAAAAGTAGAGATGCAGCGGTAAAGTCACGAGATTATGAAGCTATTATAACTGAACATGGTGGCTGGGGTAAAGA
TGCAGATGTTTTAAGAGAACTTTATAAGTCCAACAATGATAAAAACGGTGGAAGCGTTATAAATGGTATACCAGGATATA
AAAATGAAGAAATAGATAAACTTTGTATAAAACAAATGCAGGAGATGGATCCAGATAAGAGAAAAGAAATAGTATTTCAG
CTTCAAGAAAAAATAGCAGAAGAAATACCTATGATACCTATTATAAATACATCTTCTATATCAGTGCACAAAACTGATAA
ATATGATGGATATATGAATATGTATGATCATTTTGTGGTATCTCATAGTAAATTAACTTATTTACAAAGGAAATAA

Upstream 100 bases:

>100_bases
TATTTAATCACAAATTTTTTAAAAAATAATAAATTACATTTATGTAGTGAAAAAATACAGATCAATATGAGTTTATTTAT
AGTAATATAGGAGGGTTAAT

Downstream 100 bases:

>100_bases
GGTAGTTGATATTATGAATAGTAGATTTTTAAAGATTTTAGAGTATGTAGCTACTGTAGTTATTATACTTACATTAAATT
TTTTTATCCCTAGGCTTATG

Product: peptide/opine/nickel uptake ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MKTISKKSMLLVFTMLIAISFLFTGCKGGKKEAEATNANNKSEKKDVNIKLEGGDWGEPNPYKTYPRGPGMSKTNLIYDS
LIEKDEKRIIPWLAEKWEVKSNGKEYLFKIREGVKWQDGKDFTPEDVKFTFDYYKKHPPVSKNIYIGKKCFIDKVEVLKD
NYIKITVNTVNAASLENLGTTRIIPKHIWEKVEDPKKFDGKEAFIGCGPYMLEDYNKERGSYKFTAFEDYWGPKQNVKTI
EFIPVSDSILAFEKGDIDLVGSVKPDIAKKYENNKEYKLIKGHNFFGYRLCLNMNKNPEFKDKNVRQAIAYAIDEKEIID
KVMRGIGTEGSAAYLPKEHIWYNKDIKKYDYNVEKAKELLKGKNITFQIIVSNKKDNLRMAELLKLQLEKTGMKVNVKSI
DMKSRDAAVKSRDYEAIITEHGGWGKDADVLRELYKSNNDKNGGSVINGIPGYKNEEIDKLCIKQMQEMDPDKRKEIVFQ
LQEKIAEEIPMIPIINTSSISVHKTDKYDGYMNMYDHFVVSHSKLTYLQRK

Sequences:

>Translated_531_residues
MKTISKKSMLLVFTMLIAISFLFTGCKGGKKEAEATNANNKSEKKDVNIKLEGGDWGEPNPYKTYPRGPGMSKTNLIYDS
LIEKDEKRIIPWLAEKWEVKSNGKEYLFKIREGVKWQDGKDFTPEDVKFTFDYYKKHPPVSKNIYIGKKCFIDKVEVLKD
NYIKITVNTVNAASLENLGTTRIIPKHIWEKVEDPKKFDGKEAFIGCGPYMLEDYNKERGSYKFTAFEDYWGPKQNVKTI
EFIPVSDSILAFEKGDIDLVGSVKPDIAKKYENNKEYKLIKGHNFFGYRLCLNMNKNPEFKDKNVRQAIAYAIDEKEIID
KVMRGIGTEGSAAYLPKEHIWYNKDIKKYDYNVEKAKELLKGKNITFQIIVSNKKDNLRMAELLKLQLEKTGMKVNVKSI
DMKSRDAAVKSRDYEAIITEHGGWGKDADVLRELYKSNNDKNGGSVINGIPGYKNEEIDKLCIKQMQEMDPDKRKEIVFQ
LQEKIAEEIPMIPIINTSSISVHKTDKYDGYMNMYDHFVVSHSKLTYLQRK
>Mature_531_residues
MKTISKKSMLLVFTMLIAISFLFTGCKGGKKEAEATNANNKSEKKDVNIKLEGGDWGEPNPYKTYPRGPGMSKTNLIYDS
LIEKDEKRIIPWLAEKWEVKSNGKEYLFKIREGVKWQDGKDFTPEDVKFTFDYYKKHPPVSKNIYIGKKCFIDKVEVLKD
NYIKITVNTVNAASLENLGTTRIIPKHIWEKVEDPKKFDGKEAFIGCGPYMLEDYNKERGSYKFTAFEDYWGPKQNVKTI
EFIPVSDSILAFEKGDIDLVGSVKPDIAKKYENNKEYKLIKGHNFFGYRLCLNMNKNPEFKDKNVRQAIAYAIDEKEIID
KVMRGIGTEGSAAYLPKEHIWYNKDIKKYDYNVEKAKELLKGKNITFQIIVSNKKDNLRMAELLKLQLEKTGMKVNVKSI
DMKSRDAAVKSRDYEAIITEHGGWGKDADVLRELYKSNNDKNGGSVINGIPGYKNEEIDKLCIKQMQEMDPDKRKEIVFQ
LQEKIAEEIPMIPIINTSSISVHKTDKYDGYMNMYDHFVVSHSKLTYLQRK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=465, Percent_Identity=26.8817204301075, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787052, Length=435, Percent_Identity=25.7471264367816, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789887, Length=402, Percent_Identity=24.3781094527363, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787551, Length=465, Percent_Identity=22.7956989247312, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789397, Length=457, Percent_Identity=22.1006564551422, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787762, Length=418, Percent_Identity=23.6842105263158, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61309; Mature: 61309

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTISKKSMLLVFTMLIAISFLFTGCKGGKKEAEATNANNKSEKKDVNIKLEGGDWGEPN
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCCC
PYKTYPRGPGMSKTNLIYDSLIEKDEKRIIPWLAEKWEVKSNGKEYLFKIREGVKWQDGK
CCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCHHHHHCEECCCCHHHHHHHHCCCCCCCCC
DFTPEDVKFTFDYYKKHPPVSKNIYIGKKCFIDKVEVLKDNYIKITVNTVNAASLENLGT
CCCCCCEEEEEHHHHCCCCCCCCEEECHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCC
TRIIPKHIWEKVEDPKKFDGKEAFIGCGPYMLEDYNKERGSYKFTAFEDYWGPKQNVKTI
CCCCHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCCCCCEEEEEEHHCCCCCCCCEEE
EFIPVSDSILAFEKGDIDLVGSVKPDIAKKYENNKEYKLIKGHNFFGYRLCLNMNKNPEF
EEEECCCCEEEEECCCEEEECCCCHHHHHHHCCCCCEEEEECCCEEEEEEEEECCCCCCC
KDKNVRQAIAYAIDEKEIIDKVMRGIGTEGSAAYLPKEHIWYNKDIKKYDYNVEKAKELL
CCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCHHHCEECCCHHHHCCCHHHHHHHH
KGKNITFQIIVSNKKDNLRMAELLKLQLEKTGMKVNVKSIDMKSRDAAVKSRDYEAIITE
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHCCCCEEEEEC
HGGWGKDADVLRELYKSNNDKNGGSVINGIPGYKNEEIDKLCIKQMQEMDPDKRKEIVFQ
CCCCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
LQEKIAEEIPMIPIINTSSISVHKTDKYDGYMNMYDHFVVSHSKLTYLQRK
HHHHHHHHCCCEEEECCCCEEEEECCCCCCHHHHHHHHHEECCHHEEEECC
>Mature Secondary Structure
MKTISKKSMLLVFTMLIAISFLFTGCKGGKKEAEATNANNKSEKKDVNIKLEGGDWGEPN
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCCC
PYKTYPRGPGMSKTNLIYDSLIEKDEKRIIPWLAEKWEVKSNGKEYLFKIREGVKWQDGK
CCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCHHHHHCEECCCCHHHHHHHHCCCCCCCCC
DFTPEDVKFTFDYYKKHPPVSKNIYIGKKCFIDKVEVLKDNYIKITVNTVNAASLENLGT
CCCCCCEEEEEHHHHCCCCCCCCEEECHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCC
TRIIPKHIWEKVEDPKKFDGKEAFIGCGPYMLEDYNKERGSYKFTAFEDYWGPKQNVKTI
CCCCHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCCCCCEEEEEEHHCCCCCCCCEEE
EFIPVSDSILAFEKGDIDLVGSVKPDIAKKYENNKEYKLIKGHNFFGYRLCLNMNKNPEF
EEEECCCCEEEEECCCEEEECCCCHHHHHHHCCCCCEEEEECCCEEEEEEEEECCCCCCC
KDKNVRQAIAYAIDEKEIIDKVMRGIGTEGSAAYLPKEHIWYNKDIKKYDYNVEKAKELL
CCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCHHHCEECCCHHHHCCCHHHHHHHH
KGKNITFQIIVSNKKDNLRMAELLKLQLEKTGMKVNVKSIDMKSRDAAVKSRDYEAIITE
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHCCCCEEEEEC
HGGWGKDADVLRELYKSNNDKNGGSVINGIPGYKNEEIDKLCIKQMQEMDPDKRKEIVFQ
CCCCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
LQEKIAEEIPMIPIINTSSISVHKTDKYDGYMNMYDHFVVSHSKLTYLQRK
HHHHHHHHCCCEEEECCCCEEEEECCCCCCHHHHHHHHHEECCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]