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The map label for this gene is yisV [H]

Identifier: 153935225

GI number: 153935225

Start: 2259029

End: 2260522

Strand: Direct

Name: yisV [H]

Synonym: CLC_2126

Alternate gene names: 153935225

Gene position: 2259029-2260522 (Clockwise)

Preceding gene: 153934540

Following gene: 153937496

Centisome position: 60.07

GC content: 31.26

Gene sequence:

>1494_bases
ATGAATATTAAAATTGATAAGAATAGTCTAATTACTATAACTCAACAACTAGTTCATTACTTTTCGGATAGAATTATGTC
TGAATTTATAAAAGCTGGTCAAAAGCTACCTTCTATCAGAAATCTAGCCAAGGAATTAGGTATTAGCCCAATGACTATAA
TTAAAGCGTATAATAATTTAGAGCAAAATGGTTTGGTAACTACAATCCAAGGTAAAGGTACCTATGTTAATGAAAGAAAC
AGCACGGTGAAATCTAATAATATTACTGAAAAAGATAGTTTTCAGTGGCAAATGTCTGTGCCAGACTATTTATCTCGGTC
TCAATTTAGATATAATCCTAATTTATCCTACTCCAATGATTACTATAATTTGTCCGTGGCCTCATTAAATCACAAACTGT
TACCTACAAAAACTATATTAAAGGATTCTTTAAGCTTAATTCAAAATGATATAAAGCTTCTTTCTCAATATCCTCCTGCT
CAAGGTGATTATGAGTTTAGAAATATCATGTCTCAATACTTGAGATCAAAAGAAATAGCTACTTCACCGGAAAATATTTT
AGTAACTAGTGGTTCACAACAAGGAATAAGTCTTATAGCCAGCACCTTTATTGGACCTGGAGATATTGTAGTTATGGAAA
CTCCTACATATCCAGGGGCTATAGATTTATTTAAATGCAGAGGAGCAGTAATTTTAACTGTTCCTGTTGACAGCGAAGGT
ATGCGAACTGATATTTTAATGAACCTATGTGATAAACACTCGCCAAAGCTTATCTATACTATTCCAAATTTTCACAATCC
AACTGGATATAGTATGAGTTCAAACCGTAAAGCAGAGCTTTTAGATATAGCTAGATATAACGATATTCTTATAGTTGAAG
ATGATCCTTGGAATGAAATTTCATATAAAAGAGAAAAGATTAAATCAATAAAATCCATGGATACTGATGGACATGTAGTT
TATATAAAAAGTCTTAGCAAGATCCTAGGTCCTTCCTACCGGCTAGCTGTGATTATATCAGAGAGTTCGATACTCTCACG
ACTTATAGCAGCTAAATCTAATCATGATCTTGGAACATCTGTACTAATCCAAAAGACTATTATAAACTTTATCCAATCCA
ATAAAATCACATATTATATTGAAAATTTAAATAAACAGCTGGTAAAAAGACGTGATAAGGTAATTAGTTTATTGAAGAGC
CATGCACCTTCTGGTATGAAGTGGGCGATACCTGAAGGTGGAATAAATATTTGGGTTACACTTCCTAAAAATTTTAATGT
TGAAAAGCTATTATCTTACTCTATTACAACGAAGAATATTTCTTTTTTACCTGGAACCATATGTTATCCTAATGAAGTAG
AATTTAATAATCTTAGAATATGCTTCACATATTTAGATGAAGAATTCATAGAAGATACTATAATTGAGCTTTGTAACCTC
ATAAAGCTCCTATATACAACTAAAAACATTACTGACTATAGGCCTATTATTTAA

Upstream 100 bases:

>100_bases
TGATTTCGATAGCTTTCAAGCTTGAATGACGATATAATACAGATATATAATTTAACAATAATTATTATAACTGTATATAA
CACTTTGGGAGAGTTTGTTT

Downstream 100 bases:

>100_bases
TAAAAATCAGGACCTACTTTATCATCGTAAGTCCTGATTTTTTTAAAATTGTATCAATCATTTCTTAAGTTATAGTGAAA
ATTAATATTTTTCGTATAAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNIKIDKNSLITITQQLVHYFSDRIMSEFIKAGQKLPSIRNLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERN
STVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPA
QGDYEFRNIMSQYLRSKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEG
MRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSNRKAELLDIARYNDILIVEDDPWNEISYKREKIKSIKSMDTDGHVV
YIKSLSKILGPSYRLAVIISESSILSRLIAAKSNHDLGTSVLIQKTIINFIQSNKITYYIENLNKQLVKRRDKVISLLKS
HAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNL
IKLLYTTKNITDYRPII

Sequences:

>Translated_497_residues
MNIKIDKNSLITITQQLVHYFSDRIMSEFIKAGQKLPSIRNLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERN
STVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPA
QGDYEFRNIMSQYLRSKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEG
MRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSNRKAELLDIARYNDILIVEDDPWNEISYKREKIKSIKSMDTDGHVV
YIKSLSKILGPSYRLAVIISESSILSRLIAAKSNHDLGTSVLIQKTIINFIQSNKITYYIENLNKQLVKRRDKVISLLKS
HAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNL
IKLLYTTKNITDYRPII
>Mature_497_residues
MNIKIDKNSLITITQQLVHYFSDRIMSEFIKAGQKLPSIRNLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERN
STVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPA
QGDYEFRNIMSQYLRSKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEG
MRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSNRKAELLDIARYNDILIVEDDPWNEISYKREKIKSIKSMDTDGHVV
YIKSLSKILGPSYRLAVIISESSILSRLIAAKSNHDLGTSVLIQKTIINFIQSNKITYYIENLNKQLVKRRDKVISLLKS
HAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNL
IKLLYTTKNITDYRPII

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=342, Percent_Identity=26.0233918128655, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI33469970, Length=342, Percent_Identity=26.0233918128655, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1790797, Length=478, Percent_Identity=24.4769874476987, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787710, Length=476, Percent_Identity=23.5294117647059, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788722, Length=284, Percent_Identity=23.943661971831, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321236, Length=352, Percent_Identity=25, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321929, Length=204, Percent_Identity=25, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321000, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356535, Length=361, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56451; Mature: 56451

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKIDKNSLITITQQLVHYFSDRIMSEFIKAGQKLPSIRNLAKELGISPMTIIKAYNNL
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCC
EQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSND
CCCCCEEEEECCCCEECCCCCEECCCCCCCCCCCEEEECCHHHHCCCCEEECCCCCCCCC
YYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRSKEIA
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
TSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEG
CCCCCEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEHEECCCEEEEEEECCCCC
MRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSNRKAELLDIARYNDILIVEDDPWNEI
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHEEEECCCCEEEEECCCCCCH
SYKREKIKSIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKSNHDLGTS
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEEEEECHHHHHHHHHHCCCCCCCHH
VLIQKTIINFIQSNKITYYIENLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWVT
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEE
LPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNL
CCCCCCHHHHHEEEEEECCCEECCCCEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
IKLLYTTKNITDYRPII
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNIKIDKNSLITITQQLVHYFSDRIMSEFIKAGQKLPSIRNLAKELGISPMTIIKAYNNL
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCC
EQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSND
CCCCCEEEEECCCCEECCCCCEECCCCCCCCCCCEEEECCHHHHCCCCEEECCCCCCCCC
YYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRSKEIA
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
TSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEG
CCCCCEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEHEECCCEEEEEEECCCCC
MRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSNRKAELLDIARYNDILIVEDDPWNEI
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHEEEECCCCEEEEECCCCCCH
SYKREKIKSIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKSNHDLGTS
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEEEEECHHHHHHHHHHCCCCCCCHH
VLIQKTIINFIQSNKITYYIENLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWVT
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEE
LPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNL
CCCCCCHHHHHEEEEEECCCEECCCCEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
IKLLYTTKNITDYRPII
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]