| Definition | Clostridium botulinum A str. ATCC 19397, complete genome. |
|---|---|
| Accession | NC_009697 |
| Length | 3,863,450 |
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The map label for this gene is spoVD [H]
Identifier: 153934310
GI number: 153934310
Start: 2601663
End: 2603333
Strand: Reverse
Name: spoVD [H]
Synonym: CLB_2494
Alternate gene names: 153934310
Gene position: 2603333-2601663 (Counterclockwise)
Preceding gene: 153931328
Following gene: 153931109
Centisome position: 67.38
GC content: 27.23
Gene sequence:
>1671_bases ATGAGATACAGGGAGAAAAAAAAGGCTTATAAATTATTAACATTATTTATGGTTATATTTTTATTTCTTATATATAGAAT GGTTAAATTCCAGATTTTTGATGCGGAAAAATTAACTACTATGGCAGAATCTCAATACGCTTATGAAGAAGATACGAAGG ATAATAAATATAAGCTATTGGATACTAAAGGTAATGATTTGCTAAAATATAAAGAAAAATATTATGCTGTTTTAGTGCCA AGTGCCTTTAAAGATAACAAAGAAGAAAAAGATGAAGAAAAATTGTTAACAATAATGTATATTTTAAGAAATTATAATGA AAAATATGATATAACCCAAAATCAAACCATAGATAGTAGTGGTAAAAATTACTATGAAATAGATAAAATAACTTATGAAA AATTAAAAGATATAAAAGGTGTAAAAGGATTTTATACATATAAAAAACAAGAAGTAGATAAGAATATAAATGATAAAAAA GAAGCATGGAAATTAGAAAATATGTTATTAAATCCTTATAAAAATGATCAAAAAACTTTTAAAGACAAAGAGTCTTTAGA AATGAAAATATATAATAGAGTAAAAGATAATAAAACATCTAAAATAATATATAAAAAAGATTTACAAGGAGAAATTATAT CAAAAGAAGCAGAAGAGCCTAAATCTAATATAAATCCTAAACTTACATTAGATTCTAAAGTTCAAGATAGTATAAGAAAG ATTTTAAATAAAAAAGAATATAAGGCTTTTAACCAAGTAGGTGTAATTCTTTCAGAATCAGAGTCTGGAAAGATACGTGC TATGGTTCAAAAGGATGAAACATTACCTAATGTAAATATAGGGGCCGCTACACAAAATGGGTTTCCGCCAGGATCTATAT TTAAAATAATAACAGAAGAAGCTGCATTAGAAAATAATAAAGTATCCTTAAAGGATAGCTTTAAATGTACTGGAGAATTT GAAAGTAATAAGAAAGGAACTCATGGAAGCTTTAGTACAAAGGAAGCTTTTATAGTTTCTTGTAATGATATATTTTCACA AATAGGGAGAAAAGCAGGATTTGAAAATATTGATAATATGGTTAAAAAGCATGGACTATATAGCAAAGTATTAGATTTGC ACTATGAACAGCAGGGTGCTATTCAAATGGAAAAAGGAGAAAAACCGAATTTAAGTGATGGTACGTTATCTTTAGTGTCC TTTGGTCAGCTTATTAGAATAACTCCTATAGAAGCAGTTTCTATGGTGAGTACTGTGGTTAATAATGGTGTTTATGTTAA ACCCTATGTATTAGAATCTTTTGTAGATGATAAAAATAATACAATAGAAGAATTTAATACTACAAAGGAACAAATTATAG GAACCTATTCCGCAAATAGTCTAAAGGACCAAATGAAAGAGGTTGTAAAGAGGGGAACGGCGGCTTTAGCTTATGATTCT AGTATAGAAATTGGAGGAAAAACTGGTACCAATGAAAGGCAAGAAGTTAATGATAAAGGTAAAATGGAGCATCTTTCAGA TGCCTGGTTTGTAGGATTCTTCAAATCAAACAATAAATATTATACTATGGTAGTATTTATACCTAAGATAAAAACAAAAG GAGAAAGTGCTGGAACCACCTCAGTACCTATATTTTATGATATAGTTAAAGAAATAAAAGATTCTATTTAA
Upstream 100 bases:
>100_bases TTGTTACAAGAATAAGATCTTATTTAAAATGAAATAGCAATAATTTAGAATAAAACACCTTATTTTGGTTATAATTTAGC TAAAATGAGGTGTTTTTATT
Downstream 100 bases:
>100_bases ATCATATATAAAAAATAAAGTATATTTATGTGTACATGTACCTTTCTATCTTAAAGGATATATTATGTTAATAAGCACTA TTTTAGGTTTGATACCTGCA
Product: penicillin-binding protein
Products: NA
Alternate protein names: Sporulation-specific penicillin-binding protein [H]
Number of amino acids: Translated: 556; Mature: 556
Protein sequence:
>556_residues MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLLDTKGNDLLKYKEKYYAVLVP SAFKDNKEEKDEEKLLTIMYILRNYNEKYDITQNQTIDSSGKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKK EAWKLENMLLNPYKNDQKTFKDKESLEMKIYNRVKDNKTSKIIYKKDLQGEIISKEAEEPKSNINPKLTLDSKVQDSIRK ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEEAALENNKVSLKDSFKCTGEF ESNKKGTHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNMVKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVS FGQLIRITPIEAVSMVSTVVNNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGTYSANSLKDQMKEVVKRGTAALAYDS SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTTSVPIFYDIVKEIKDSI
Sequences:
>Translated_556_residues MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLLDTKGNDLLKYKEKYYAVLVP SAFKDNKEEKDEEKLLTIMYILRNYNEKYDITQNQTIDSSGKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKK EAWKLENMLLNPYKNDQKTFKDKESLEMKIYNRVKDNKTSKIIYKKDLQGEIISKEAEEPKSNINPKLTLDSKVQDSIRK ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEEAALENNKVSLKDSFKCTGEF ESNKKGTHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNMVKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVS FGQLIRITPIEAVSMVSTVVNNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGTYSANSLKDQMKEVVKRGTAALAYDS SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTTSVPIFYDIVKEIKDSI >Mature_556_residues MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLLDTKGNDLLKYKEKYYAVLVP SAFKDNKEEKDEEKLLTIMYILRNYNEKYDITQNQTIDSSGKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKK EAWKLENMLLNPYKNDQKTFKDKESLEMKIYNRVKDNKTSKIIYKKDLQGEIISKEAEEPKSNINPKLTLDSKVQDSIRK ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEEAALENNKVSLKDSFKCTGEF ESNKKGTHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNMVKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVS FGQLIRITPIEAVSMVSTVVNNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGTYSANSLKDQMKEVVKRGTAALAYDS SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTTSVPIFYDIVKEIKDSI
Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PASTA domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005543 - InterPro: IPR005311 - InterPro: IPR001460 - InterPro: IPR011927 [H]
Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: NA
Molecular weight: Translated: 63859; Mature: 63859
Theoretical pI: Translated: 9.29; Mature: 9.29
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCCCCCCEEEE DTKGNDLLKYKEKYYAVLVPSAFKDNKEEKDEEKLLTIMYILRNYNEKYDITQNQTIDSS ECCCCHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC GKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKKEAWKLENMLLNPYKNDQKTF CCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHH KDKESLEMKIYNRVKDNKTSKIIYKKDLQGEIISKEAEEPKSNINPKLTLDSKVQDSIRK CCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCHHHCCCCEEEECHHHHHHHHH ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEE HHCHHHHHHHHHHCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH AALENNKVSLKDSFKCTGEFESNKKGTHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNM HHHCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHH VKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVSFGQLIRITPIEAVSMVSTVV HHHCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHHHHH NNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGTYSANSLKDQMKEVVKRGTAALAYDS HCCEEEEHHHHHHHHCCCCCCHHHHCCCHHHHEECCCCHHHHHHHHHHHHCCCEEEEECC SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTT CEEECCCCCCCHHHHCCCCCCHHHCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCC SVPIFYDIVKEIKDSI CCHHHHHHHHHHHHCC >Mature Secondary Structure MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCCCCCCEEEE DTKGNDLLKYKEKYYAVLVPSAFKDNKEEKDEEKLLTIMYILRNYNEKYDITQNQTIDSS ECCCCHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC GKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKKEAWKLENMLLNPYKNDQKTF CCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHH KDKESLEMKIYNRVKDNKTSKIIYKKDLQGEIISKEAEEPKSNINPKLTLDSKVQDSIRK CCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCHHHCCCCEEEECHHHHHHHHH ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEE HHCHHHHHHHHHHCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH AALENNKVSLKDSFKCTGEFESNKKGTHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNM HHHCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHH VKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVSFGQLIRITPIEAVSMVSTVV HHHCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHHHHH NNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGTYSANSLKDQMKEVVKRGTAALAYDS HCCEEEEHHHHHHHHCCCCCCHHHHCCCHHHHEECCCCHHHHHHHHHHHHCCCEEEEECC SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTT CEEECCCCCCCHHHHCCCCCCHHHCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCC SVPIFYDIVKEIKDSI CCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8289242; 9384377; 8244929; 8436954 [H]