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The map label for this gene is fur [H]

Identifier: 153932039

GI number: 153932039

Start: 2611481

End: 2611933

Strand: Reverse

Name: fur [H]

Synonym: CLB_2501

Alternate gene names: 153932039

Gene position: 2611933-2611481 (Counterclockwise)

Preceding gene: 153932529

Following gene: 153931086

Centisome position: 67.61

GC content: 30.02

Gene sequence:

>453_bases
GTGGCGGATTTTAAGAGAGAAGAAATTGAAAAGTTAAAGGAAGAATTAAAATCTAAGGGATATAAGTTAACTCCTCAAAG
AAGAGCGATTATAGATATGATAAAAAAACATGAGGGTAGCCATTTAACTACAGAAGAGTTATACGATTTAGTAAAAGAAG
AATGCCCAGAAATAGGTCTTGCAACGGTATATAGAACAGTACAACTTTTAGAAGAAATGGGTGTTATATATAAATTAGAC
CTAGATGATGGATGTAGTAGATATGAATTGGTAAATGAAGATGAAAATCATCAGCATCATCACCTAATATGTAGTAAATG
CAATAAGGTAATAGAGGTTAAGGATGATTTCTTAGAAGATTTAGAAGAAAACATTGAAGAAGAATATAATTTTAAAATAG
AGAATCATAGTTTAAAGTTCTACGGTATCTGCAAGGAATGTCAAGGAAAATAA

Upstream 100 bases:

>100_bases
ATATATAATTTGAAATTACAGATAAAGATTATCAATTGACAATAGAACAATACTGTATTAAACTTATATTAAAATAAAGT
AGTTAAAGGTGGAATGAAAA

Downstream 100 bases:

>100_bases
ATAATAAAACTATGATGAAAACATAAAAGAAAAAGGAGGGAAGAAGTTTGCGAGTGGACAAAGAAAAAGATAAAGCAAAA
GATAGAGTAAAAGATAAGGA

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MADFKREEIEKLKEELKSKGYKLTPQRRAIIDMIKKHEGSHLTTEELYDLVKEECPEIGLATVYRTVQLLEEMGVIYKLD
LDDGCSRYELVNEDENHQHHHLICSKCNKVIEVKDDFLEDLEENIEEEYNFKIENHSLKFYGICKECQGK

Sequences:

>Translated_150_residues
MADFKREEIEKLKEELKSKGYKLTPQRRAIIDMIKKHEGSHLTTEELYDLVKEECPEIGLATVYRTVQLLEEMGVIYKLD
LDDGCSRYELVNEDENHQHHHLICSKCNKVIEVKDDFLEDLEENIEEEYNFKIENHSLKFYGICKECQGK
>Mature_149_residues
ADFKREEIEKLKEELKSKGYKLTPQRRAIIDMIKKHEGSHLTTEELYDLVKEECPEIGLATVYRTVQLLEEMGVIYKLDL
DDGCSRYELVNEDENHQHHHLICSKCNKVIEVKDDFLEDLEENIEEEYNFKIENHSLKFYGICKECQGK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=131, Percent_Identity=36.6412213740458, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI87082363, Length=129, Percent_Identity=24.8062015503876, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17754; Mature: 17623

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFKREEIEKLKEELKSKGYKLTPQRRAIIDMIKKHEGSHLTTEELYDLVKEECPEIGL
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCH
ATVYRTVQLLEEMGVIYKLDLDDGCSRYELVNEDENHQHHHLICSKCNKVIEVKDDFLED
HHHHHHHHHHHHCCCEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEENIEEEYNFKIENHSLKFYGICKECQGK
HHHHHHHHHCEEECCCCEEEEEECHHCCCC
>Mature Secondary Structure 
ADFKREEIEKLKEELKSKGYKLTPQRRAIIDMIKKHEGSHLTTEELYDLVKEECPEIGL
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCH
ATVYRTVQLLEEMGVIYKLDLDDGCSRYELVNEDENHQHHHLICSKCNKVIEVKDDFLED
HHHHHHHHHHHHCCCEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEENIEEEYNFKIENHSLKFYGICKECQGK
HHHHHHHHHCEEECCCCEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]