Click here to switch to the map view.

The map label for this gene is coaD

Identifier: 153931465

GI number: 153931465

Start: 2501798

End: 2502292

Strand: Reverse

Name: coaD

Synonym: CLB_2366

Alternate gene names: 153931465

Gene position: 2502292-2501798 (Counterclockwise)

Preceding gene: 153934015

Following gene: 153931211

Centisome position: 64.77

GC content: 30.3

Gene sequence:

>495_bases
ATGAAAACTGCAGTGTACCCAGGAAGTTTTGACCCTATAACTAAGGGACATTTAAATATAATTAAAAGAGCTTCTAAGGT
TTGTGATAAACTAATAGTGGCGGTACTTGTAAATCCAGAAAAGAAGGGACTTTTTTCAGTAGATGAGAGAGTAGAAATGA
TAAAAAGAGTTACTAAGAAACATAGCAATGTAGAAGTGCAATGTTTTAGTGGGCTTTTAATAGATTTTATGAAAGAGAAG
AAATCCAAGGTTATAATTAAAGGCCTTAGAACTATGTCAGATTTTGAATATGAATTTAAGATGGCTCTTATGAATAACAA
ATTAGATCCTAATATAGAAACAGTATTTATGATGACCAATGCAAAATATTCTTATTTAAGTTCATCCTCAGTAAAGCAGG
TAGCTATGTTTGGTGGATGTATAAAGGATTTGGTACCGGATGAAATAATACCAGATATTAAAAAGAAGATAAATCATAAA
AAGGAATGTATTTAG

Upstream 100 bases:

>100_bases
TCAGAAGAAATATATGAAGGAACTGAAAGAATAAAATTATTTGATCATAGAAAATATGGAAACACTACCGTTTGTTTTTA
TAAATTTAAGGAGGATTAAA

Downstream 100 bases:

>100_bases
GAGGGTTACTTAATGGATGTTATTAAGCTTTTAGCATATCTAGAAGAACTAATAGAATCAGGTTCAAGTATTCCTTTAAC
GGGGAAAGTTACTATAAATA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKTAVYPGSFDPITKGHLNIIKRASKVCDKLIVAVLVNPEKKGLFSVDERVEMIKRVTKKHSNVEVQCFSGLLIDFMKEK
KSKVIIKGLRTMSDFEYEFKMALMNNKLDPNIETVFMMTNAKYSYLSSSSVKQVAMFGGCIKDLVPDEIIPDIKKKINHK
KECI

Sequences:

>Translated_164_residues
MKTAVYPGSFDPITKGHLNIIKRASKVCDKLIVAVLVNPEKKGLFSVDERVEMIKRVTKKHSNVEVQCFSGLLIDFMKEK
KSKVIIKGLRTMSDFEYEFKMALMNNKLDPNIETVFMMTNAKYSYLSSSSVKQVAMFGGCIKDLVPDEIIPDIKKKINHK
KECI
>Mature_164_residues
MKTAVYPGSFDPITKGHLNIIKRASKVCDKLIVAVLVNPEKKGLFSVDERVEMIKRVTKKHSNVEVQCFSGLLIDFMKEK
KSKVIIKGLRTMSDFEYEFKMALMNNKLDPNIETVFMMTNAKYSYLSSSSVKQVAMFGGCIKDLVPDEIIPDIKKKINHK
KECI

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=41.025641025641, Blast_Score=150, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CLOB1 (A7FW59)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384670.1
- ProteinModelPortal:   A7FW59
- SMR:   A7FW59
- STRING:   A7FW59
- GeneID:   5394653
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2366
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   CBOT441770:CLB_2366-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18667; Mature: 18667

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAVYPGSFDPITKGHLNIIKRASKVCDKLIVAVLVNPEKKGLFSVDERVEMIKRVTKK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
HSNVEVQCFSGLLIDFMKEKKSKVIIKGLRTMSDFEYEFKMALMNNKLDPNIETVFMMTN
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
AKYSYLSSSSVKQVAMFGGCIKDLVPDEIIPDIKKKINHKKECI
CCHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MKTAVYPGSFDPITKGHLNIIKRASKVCDKLIVAVLVNPEKKGLFSVDERVEMIKRVTKK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
HSNVEVQCFSGLLIDFMKEKKSKVIIKGLRTMSDFEYEFKMALMNNKLDPNIETVFMMTN
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
AKYSYLSSSSVKQVAMFGGCIKDLVPDEIIPDIKKKINHKKECI
CCHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA