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The map label for this gene is xerC [H]

Identifier: 153931223

GI number: 153931223

Start: 2582217

End: 2583062

Strand: Reverse

Name: xerC [H]

Synonym: CLB_2461

Alternate gene names: 153931223

Gene position: 2583062-2582217 (Counterclockwise)

Preceding gene: 153931569

Following gene: 153931948

Centisome position: 66.86

GC content: 30.14

Gene sequence:

>846_bases
ATGACAAGCGATATAGAAGGAAAAATAGCAATATACTTAGCTGCTAAAAAACTTGATGGCCTAAGTTTAAAAACATTGCT
GAATTATAAATATAATTTAGCAATATTTGCAGATTATTTAAGAAAACCATTAGCTACCATAAATGCAATGGATTTAAGAA
TATTTTTAGCACAAAGGTGTAAAAAAATGAAAGCAAGTAGTGTAAATGGTCAAATATCTATATTGAAAAGTTTTTTCGGA
TGGTTGCATATGGAAGAATATATACCAAAGAATCCAAGCTTAAAATTAAAGCAGACTAAGCAACCTAAAAGAGTACGTCG
TGCATTAAATCAGGAAGAATTAGAATTGTTAAGACAAGCTTGTAAAACTAATAGAGAAAAGGCTTTGCTAGAATTTTTAA
TTTCTACTGGCTGTAGACTTAGTGAAGTAGTAGGAATTGATAAAAATGATATAGACTGGAATGAAATGAGTTTACATGTT
ATAGGTAAGGGAAATAAAGAGAGAAAAGTATATTTTGATGTTAAAACTAAAATACTGCTAAAAAAATACTTAGCAATAAG
GAATGATATAACTCCAGCTTTATTTGTAGCTAGCAAAGGAACTCATGCAAGATTAGGTGGAAGGTCTATACAAAGAGAAA
TTAAAAAAATTGCAAAGAGAGTAGGGACAGAAAAGTCAATATATCCACATTTGTTTAGACATAGTTTCGCAACTGGAAAA
ATTAATAGTGGTATGCCTCTTCCGGTGCTACAGCACATTATGGGGCATGAAAATCCAGCAACGACACAAATTTATGCTGA
GCTAAGTGAAGAAAATATAAAGCATGAATATAAAAAAATATCTTAA

Upstream 100 bases:

>100_bases
ATTATCTTTGGAGTTTCCAGAAATAAATCAATTAAAAGCTAGAGAACTAGTTGAAGAAGTTCTATATAAATATAATATAT
TGCCACAAGAAAAAGCATTA

Downstream 100 bases:

>100_bases
GGAGTGTAACTATGGTTAAAATGAGAGGAAAAACAAAAATACTTGTACTACCATACAGGAATTTCAAACATAGAATTAGA
CTTACACAGAGATATGAGAA

Product: phage integrase family site specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTSDIEGKIAIYLAAKKLDGLSLKTLLNYKYNLAIFADYLRKPLATINAMDLRIFLAQRCKKMKASSVNGQISILKSFFG
WLHMEEYIPKNPSLKLKQTKQPKRVRRALNQEELELLRQACKTNREKALLEFLISTGCRLSEVVGIDKNDIDWNEMSLHV
IGKGNKERKVYFDVKTKILLKKYLAIRNDITPALFVASKGTHARLGGRSIQREIKKIAKRVGTEKSIYPHLFRHSFATGK
INSGMPLPVLQHIMGHENPATTQIYAELSEENIKHEYKKIS

Sequences:

>Translated_281_residues
MTSDIEGKIAIYLAAKKLDGLSLKTLLNYKYNLAIFADYLRKPLATINAMDLRIFLAQRCKKMKASSVNGQISILKSFFG
WLHMEEYIPKNPSLKLKQTKQPKRVRRALNQEELELLRQACKTNREKALLEFLISTGCRLSEVVGIDKNDIDWNEMSLHV
IGKGNKERKVYFDVKTKILLKKYLAIRNDITPALFVASKGTHARLGGRSIQREIKKIAKRVGTEKSIYPHLFRHSFATGK
INSGMPLPVLQHIMGHENPATTQIYAELSEENIKHEYKKIS
>Mature_280_residues
TSDIEGKIAIYLAAKKLDGLSLKTLLNYKYNLAIFADYLRKPLATINAMDLRIFLAQRCKKMKASSVNGQISILKSFFGW
LHMEEYIPKNPSLKLKQTKQPKRVRRALNQEELELLRQACKTNREKALLEFLISTGCRLSEVVGIDKNDIDWNEMSLHVI
GKGNKERKVYFDVKTKILLKKYLAIRNDITPALFVASKGTHARLGGRSIQREIKKIAKRVGTEKSIYPHLFRHSFATGKI
NSGMPLPVLQHIMGHENPATTQIYAELSEENIKHEYKKIS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=31.1864406779661, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=28.0276816608997, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32140; Mature: 32009

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDIEGKIAIYLAAKKLDGLSLKTLLNYKYNLAIFADYLRKPLATINAMDLRIFLAQRC
CCCCCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKMKASSVNGQISILKSFFGWLHMEEYIPKNPSLKLKQTKQPKRVRRALNQEELELLRQA
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHCCHHHHHHHHHH
CKTNREKALLEFLISTGCRLSEVVGIDKNDIDWNEMSLHVIGKGNKERKVYFDVKTKILL
HHCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEHHHHHHH
KKYLAIRNDITPALFVASKGTHARLGGRSIQREIKKIAKRVGTEKSIYPHLFRHSFATGK
HHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
INSGMPLPVLQHIMGHENPATTQIYAELSEENIKHEYKKIS
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSDIEGKIAIYLAAKKLDGLSLKTLLNYKYNLAIFADYLRKPLATINAMDLRIFLAQRC
CCCCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKMKASSVNGQISILKSFFGWLHMEEYIPKNPSLKLKQTKQPKRVRRALNQEELELLRQA
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHCCHHHHHHHHHH
CKTNREKALLEFLISTGCRLSEVVGIDKNDIDWNEMSLHVIGKGNKERKVYFDVKTKILL
HHCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEHHHHHHH
KKYLAIRNDITPALFVASKGTHARLGGRSIQREIKKIAKRVGTEKSIYPHLFRHSFATGK
HHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
INSGMPLPVLQHIMGHENPATTQIYAELSEENIKHEYKKIS
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]