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The map label for this gene is uvrB [H]

Identifier: 152977385

GI number: 152977385

Start: 3765971

End: 3767947

Strand: Reverse

Name: uvrB [H]

Synonym: Bcer98_3710

Alternate gene names: 152977385

Gene position: 3767947-3765971 (Counterclockwise)

Preceding gene: 152977386

Following gene: 152977384

Centisome position: 92.19

GC content: 40.67

Gene sequence:

>1977_bases
GTGGAACGTGAATTTGAAATTGTCTCAGAATACTCCCCGCAGGGTGATCAGCCGAAAGCAATCGAGCAGCTTGTCAAGGG
AATTCAAAACGGTAAGAGACATCAAGTGTTGCTTGGAGCGACAGGAACGGGTAAAACATTTACAATTTCGAATGTAATTA
AAGAAGTGAAAAAGCCGACACTTGTTATGGCTCATAATAAAACGTTAGCAGGACAACTGTATAGCGAGCTAAAAGATTTC
TTTCCAAACAATGCAGTTGAGTATTTCGTTAGTTATTATGATTATTATCAACCGGAAGCATATGTACCACAAACCGATAC
GTTTATTGAAAAAGATGCACAAATTAATGATGAAATTGATAAGCTGCGCCACTCGGCAACGTCGGCTTTATTTGAGCGTG
ATGATGTCATTATTGTCGCAAGTGTATCTTGCATTTATGGTTTAGGTTCTCCAGAAGAGTATCGTGAGCTTGTCGTTTCA
CTGCGCGTTGGCATGGAGAAAGATCGCAACCAGTTGCTGCGCGAGCTCGTTGATGTACAGTATGGACGCAATGATATTGA
TTTTCAGCGCGGAACGTTTCGCGTTCGCGGCGATGTCGTAGAGATTTTCCCAGCATCTCTTGATGAACATTGCATCAGAA
TCGAGTTTTTTGGAGATGAAATTGATCGCATTCGAGAAGTGGATGCATTAACAGGTGAAGTATTGGCAGAACGTGAACAT
GTAGCGATCTTTCCAGCATCTCACTTCGTTACACGTGAAGAGAAGATGAAAGTCGCGATTGAAAATATTGAAAAAGAATT
AGAAGAACGTTTAAAAGAATTAAATGAGCAAGGGAAACTATTAGAAGCGCAGCGCATCGAGCAGCGGACGCGTTATGATT
TAGAAATGATGCGTGAGATGGGATTTTGCTCAGGGATTGAAAACTACTCTCGTCATTTAACACTCCGTCCTGCTGGTTCA
ACGCCATATACATTATTAGATTATTTTCCTAAGGACTTTCTAATCGTAATGGATGAATCTCATGTAACGGTTCCGCAAGT
AAGAGCGATGTATAATGGCGACCAGGCGCGTAAGCAAGTGCTTGTTGACCATGGGTTCCGCTTACCTTCAGCTTTAGATA
ATAGACCGCTTAAGTTTGAAGAGTTTGAAGAGAAAGCAAATCAAATTATATATGTTTCGGCAACGCCAGGTCCATATGAG
TTAGAGCATGCACCAGAAGTTGTAGAGCAAATTATTCGTCCAACCGGGCTCTTAGATCCGAAAATTGAAGTAAGACCAAT
TGAAGGACAGATTGATGACTTATTAGGAGAAATACAAGAGCGAATTGCGAAAAATGAGCGCGTTTTAATTACGACATTAA
CGAAGAAAATGTCAGAGGATTTAACAGATTACTTAAAGGATGTTGGGATTAAGGTAAATTATCTTCATTCTGAAATTAAA
ACGCTTGAGCGAATTGAAATCATTCGTGATCTTCGTCTTGGCAAGTTCGACGTACTTGTTGGAATTAACTTATTGCGAGA
AGGTCTTGATATTCCAGAAGTATCACTTGTTGCGATTTTAGATGCGGATAAAGAAGGATTTTTGCGCTCAGAGCGATCAC
TCATTCAAACGATTGGCCGTGCTGCGCGTAATGAGAACGGTCACGTTATTATGTATGCAGATCATATAACAAAATCGATG
CAAATCGCCATTGATGAAACGAAACGTCGTCGTGAAAAACAAGAGGCTTACAATAAAGAGCATGGCATCACACCAAAAAC
AATTCAAAAAGAAGTGCGCGATGTGATTCGTGCGACAGTAGCGGCGGAAGAAACAGAAGTATATGAAGCAACGGCAATGA
AGAAAATGACAAAGAAAGAACGAGAAAAAACGATTGCGAAGATGGAAGCAGAAATGAAGGAAGCAGCAAAAGCTTTAGAT
TTCGAGCGTGCGGCTGAGCTAAGAGATTTAATACTAGAACTAAAAGCGGAAGGGTGA

Upstream 100 bases:

>100_bases
TTGTCGAAAACTTTACCGAATATTTGTTCGTTTTCTTGGTTTTTTTATGGGCATTCGTGGTAAAATGGGAATACAGATTT
TTTAGAGGAGGTCGGATTTG

Downstream 100 bases:

>100_bases
AGAGAGTGAGCAAAGACCATATCGTTGTAAAAGGTGCGAGAGCACATAACTTAAAAAATATTGATGTAACCATTCCGAGA
AATCAACTTGTTGTTGTGAC

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MEREFEIVSEYSPQGDQPKAIEQLVKGIQNGKRHQVLLGATGTGKTFTISNVIKEVKKPTLVMAHNKTLAGQLYSELKDF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDAQINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGSPEEYRELVVS
LRVGMEKDRNQLLRELVDVQYGRNDIDFQRGTFRVRGDVVEIFPASLDEHCIRIEFFGDEIDRIREVDALTGEVLAEREH
VAIFPASHFVTREEKMKVAIENIEKELEERLKELNEQGKLLEAQRIEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGS
TPYTLLDYFPKDFLIVMDESHVTVPQVRAMYNGDQARKQVLVDHGFRLPSALDNRPLKFEEFEEKANQIIYVSATPGPYE
LEHAPEVVEQIIRPTGLLDPKIEVRPIEGQIDDLLGEIQERIAKNERVLITTLTKKMSEDLTDYLKDVGIKVNYLHSEIK
TLERIEIIRDLRLGKFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNENGHVIMYADHITKSM
QIAIDETKRRREKQEAYNKEHGITPKTIQKEVRDVIRATVAAEETEVYEATAMKKMTKKEREKTIAKMEAEMKEAAKALD
FERAAELRDLILELKAEG

Sequences:

>Translated_658_residues
MEREFEIVSEYSPQGDQPKAIEQLVKGIQNGKRHQVLLGATGTGKTFTISNVIKEVKKPTLVMAHNKTLAGQLYSELKDF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDAQINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGSPEEYRELVVS
LRVGMEKDRNQLLRELVDVQYGRNDIDFQRGTFRVRGDVVEIFPASLDEHCIRIEFFGDEIDRIREVDALTGEVLAEREH
VAIFPASHFVTREEKMKVAIENIEKELEERLKELNEQGKLLEAQRIEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGS
TPYTLLDYFPKDFLIVMDESHVTVPQVRAMYNGDQARKQVLVDHGFRLPSALDNRPLKFEEFEEKANQIIYVSATPGPYE
LEHAPEVVEQIIRPTGLLDPKIEVRPIEGQIDDLLGEIQERIAKNERVLITTLTKKMSEDLTDYLKDVGIKVNYLHSEIK
TLERIEIIRDLRLGKFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNENGHVIMYADHITKSM
QIAIDETKRRREKQEAYNKEHGITPKTIQKEVRDVIRATVAAEETEVYEATAMKKMTKKEREKTIAKMEAEMKEAAKALD
FERAAELRDLILELKAEG
>Mature_658_residues
MEREFEIVSEYSPQGDQPKAIEQLVKGIQNGKRHQVLLGATGTGKTFTISNVIKEVKKPTLVMAHNKTLAGQLYSELKDF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDAQINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGSPEEYRELVVS
LRVGMEKDRNQLLRELVDVQYGRNDIDFQRGTFRVRGDVVEIFPASLDEHCIRIEFFGDEIDRIREVDALTGEVLAEREH
VAIFPASHFVTREEKMKVAIENIEKELEERLKELNEQGKLLEAQRIEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGS
TPYTLLDYFPKDFLIVMDESHVTVPQVRAMYNGDQARKQVLVDHGFRLPSALDNRPLKFEEFEEKANQIIYVSATPGPYE
LEHAPEVVEQIIRPTGLLDPKIEVRPIEGQIDDLLGEIQERIAKNERVLITTLTKKMSEDLTDYLKDVGIKVNYLHSEIK
TLERIEIIRDLRLGKFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNENGHVIMYADHITKSM
QIAIDETKRRREKQEAYNKEHGITPKTIQKEVRDVIRATVAAEETEVYEATAMKKMTKKEREKTIAKMEAEMKEAAKALD
FERAAELRDLILELKAEG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=666, Percent_Identity=58.8588588588589, Blast_Score=782, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 75618; Mature: 75618

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEREFEIVSEYSPQGDQPKAIEQLVKGIQNGKRHQVLLGATGTGKTFTISNVIKEVKKPT
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHCCCE
LVMAHNKTLAGQLYSELKDFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDAQINDEID
EEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHH
KLRHSATSALFERDDVIIVASVSCIYGLGSPEEYRELVVSLRVGMEKDRNQLLRELVDVQ
HHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YGRNDIDFQRGTFRVRGDVVEIFPASLDEHCIRIEFFGDEIDRIREVDALTGEVLAEREH
CCCCCCCCCCCEEEEECCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
VAIFPASHFVTREEKMKVAIENIEKELEERLKELNEQGKLLEAQRIEQRTRYDLEMMREM
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GFCSGIENYSRHLTLRPAGSTPYTLLDYFPKDFLIVMDESHVTVPQVRAMYNGDQARKQV
HHHCCCCHHHCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHH
LVDHGFRLPSALDNRPLKFEEFEEKANQIIYVSATPGPYELEHAPEVVEQIIRPTGLLDP
HHHCCCCCCHHCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCC
KIEVRPIEGQIDDLLGEIQERIAKNERVLITTLTKKMSEDLTDYLKDVGIKVNYLHSEIK
CEEEEECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
TLERIEIIRDLRLGKFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
AARNENGHVIMYADHITKSMQIAIDETKRRREKQEAYNKEHGITPKTIQKEVRDVIRATV
HHCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAEETEVYEATAMKKMTKKEREKTIAKMEAEMKEAAKALDFERAAELRDLILELKAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEREFEIVSEYSPQGDQPKAIEQLVKGIQNGKRHQVLLGATGTGKTFTISNVIKEVKKPT
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHCCCE
LVMAHNKTLAGQLYSELKDFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDAQINDEID
EEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHH
KLRHSATSALFERDDVIIVASVSCIYGLGSPEEYRELVVSLRVGMEKDRNQLLRELVDVQ
HHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YGRNDIDFQRGTFRVRGDVVEIFPASLDEHCIRIEFFGDEIDRIREVDALTGEVLAEREH
CCCCCCCCCCCEEEEECCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
VAIFPASHFVTREEKMKVAIENIEKELEERLKELNEQGKLLEAQRIEQRTRYDLEMMREM
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GFCSGIENYSRHLTLRPAGSTPYTLLDYFPKDFLIVMDESHVTVPQVRAMYNGDQARKQV
HHHCCCCHHHCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHH
LVDHGFRLPSALDNRPLKFEEFEEKANQIIYVSATPGPYELEHAPEVVEQIIRPTGLLDP
HHHCCCCCCHHCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCC
KIEVRPIEGQIDDLLGEIQERIAKNERVLITTLTKKMSEDLTDYLKDVGIKVNYLHSEIK
CEEEEECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
TLERIEIIRDLRLGKFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
AARNENGHVIMYADHITKSMQIAIDETKRRREKQEAYNKEHGITPKTIQKEVRDVIRATV
HHCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAEETEVYEATAMKKMTKKEREKTIAKMEAEMKEAAKALDFERAAELRDLILELKAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]