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The map label for this gene is trxB [H]

Identifier: 152977376

GI number: 152977376

Start: 3756251

End: 3757207

Strand: Reverse

Name: trxB [H]

Synonym: Bcer98_3701

Alternate gene names: 152977376

Gene position: 3757207-3756251 (Counterclockwise)

Preceding gene: 152977377

Following gene: 152977375

Centisome position: 91.93

GC content: 39.6

Gene sequence:

>957_bases
GTGTCAGAAGAAAAAATTTATGATGTCATTATTATTGGTGCTGGACCAGCTGGGATGACAGCTGCAGTTTATACATCTCG
TGCGAATTTAAGTACACTTATGTTAGAACGTGGTATTCCAGGCGGACAAATGGCAAATACAGAAGAGGTAGAGAACTATC
CAGGTTATGAATCCATTTTAGGGCCGGATTTATCCAATAAAATGTTTGAGCACGCAAAGAAATTTGGTGCGGAATACGCA
TATGGTGACGTAAAAGAAGTCATCGATGGAAAAGAATATAAAACAATTATAGCAGGTAAAAAAGAGTACAAAGCACGTGC
CATTATCATTGCAAGTGGGGCAGAGTATAAAAAACTTGGTGTTCCAGGTGAAAAAGAACTTGGGGGACGCGGTGTATCTT
ACTGCGCAGTATGTGATGGTGCATTCTTTAAAGAGAAAGAACTTGTTGTTATCGGTGGTGGAGACTCAGCGGTTGAAGAG
GGTGTATATTTAACACGCTTCGCTTCAAAAGTAACAATCATTCATCGTCGCGATGCTCTTCGGGCACAGAAAATCCTGCA
AGACCGCGCTTTCCAAAATGAGAAAATAGACTTCATTTGGAATCACACTGTAAAACAAATTAACGAGGAAAACGGTAAAG
TAGGTAGTGTTACAATTGTAGATGTGAACACTGGTGAAGAAACAGAATTTAAAGCGGACGGTGTCTTCGTTTATATCGGT
ATGTTACCATTATCAAAACCATTTGCTGCATTAGGTATTACAAATGAAAATGGTTATATTGAAACAAATGAGCGCATGGA
AACGAAAGTACCTGGTATCTTCGCAGCTGGCGATATTCGTGAAAAAATGCTTCGCCAAATTGTTACAGCAACTGGCGACG
GTAGTATCGCAGCACAAAGCGTACAGCACTATGTAGAAGAGTTATTAGAGGAATTAAACACTGTAACGGAAAAATAA

Upstream 100 bases:

>100_bases
AAGCAGTAAGACGTACACATGCATAGGCATATCACTAGGAAAAAGCAAATGCTAACAGTATAATGAGGGTAAGTTGTAGG
TATGAATAGGAGTGAATAGT

Downstream 100 bases:

>100_bases
AAAGTACGATTTTTTTAGACGAAAGTGATCTGCAAATGATAGCTTTCGTCTTTTCATTTTTACTCAAAATGTCAAATGTT
TGTAAAAAAATGTTTGGATT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMLERGIPGGQMANTEEVENYPGYESILGPDLSNKMFEHAKKFGAEYA
YGDVKEVIDGKEYKTIIAGKKEYKARAIIIASGAEYKKLGVPGEKELGGRGVSYCAVCDGAFFKEKELVVIGGGDSAVEE
GVYLTRFASKVTIIHRRDALRAQKILQDRAFQNEKIDFIWNHTVKQINEENGKVGSVTIVDVNTGEETEFKADGVFVYIG
MLPLSKPFAALGITNENGYIETNERMETKVPGIFAAGDIREKMLRQIVTATGDGSIAAQSVQHYVEELLEELNTVTEK

Sequences:

>Translated_318_residues
MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMLERGIPGGQMANTEEVENYPGYESILGPDLSNKMFEHAKKFGAEYA
YGDVKEVIDGKEYKTIIAGKKEYKARAIIIASGAEYKKLGVPGEKELGGRGVSYCAVCDGAFFKEKELVVIGGGDSAVEE
GVYLTRFASKVTIIHRRDALRAQKILQDRAFQNEKIDFIWNHTVKQINEENGKVGSVTIVDVNTGEETEFKADGVFVYIG
MLPLSKPFAALGITNENGYIETNERMETKVPGIFAAGDIREKMLRQIVTATGDGSIAAQSVQHYVEELLEELNTVTEK
>Mature_317_residues
SEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMLERGIPGGQMANTEEVENYPGYESILGPDLSNKMFEHAKKFGAEYAY
GDVKEVIDGKEYKTIIAGKKEYKARAIIIASGAEYKKLGVPGEKELGGRGVSYCAVCDGAFFKEKELVVIGGGDSAVEEG
VYLTRFASKVTIIHRRDALRAQKILQDRAFQNEKIDFIWNHTVKQINEENGKVGSVTIVDVNTGEETEFKADGVFVYIGM
LPLSKPFAALGITNENGYIETNERMETKVPGIFAAGDIREKMLRQIVTATGDGSIAAQSVQHYVEELLEELNTVTEK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=38.6292834890966, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=33.1189710610932, Blast_Score=155, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=39.297124600639, Blast_Score=211, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=37.5, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34815; Mature: 34684

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMLERGIPGGQMANTEEVENYPGYESIL
CCCCEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHC
GPDLSNKMFEHAKKFGAEYAYGDVKEVIDGKEYKTIIAGKKEYKARAIIIASGAEYKKLG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCEEECC
VPGEKELGGRGVSYCAVCDGAFFKEKELVVIGGGDSAVEEGVYLTRFASKVTIIHRRDAL
CCCCHHCCCCCCEEEEEECCCCCCCCCEEEEECCCHHHHCCEEEEEHHHEEEEEEHHHHH
RAQKILQDRAFQNEKIDFIWNHTVKQINEENGKVGSVTIVDVNTGEETEFKADGVFVYIG
HHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCEEEEEEEEECCCCCCEEECCCEEEEEE
MLPLSKPFAALGITNENGYIETNERMETKVPGIFAAGDIREKMLRQIVTATGDGSIAAQS
ECCCCCCCEEEEEECCCCEEECCCCHHHCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHH
VQHYVEELLEELNTVTEK
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMLERGIPGGQMANTEEVENYPGYESIL
CCCEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHC
GPDLSNKMFEHAKKFGAEYAYGDVKEVIDGKEYKTIIAGKKEYKARAIIIASGAEYKKLG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCEEECC
VPGEKELGGRGVSYCAVCDGAFFKEKELVVIGGGDSAVEEGVYLTRFASKVTIIHRRDAL
CCCCHHCCCCCCEEEEEECCCCCCCCCEEEEECCCHHHHCCEEEEEHHHEEEEEEHHHHH
RAQKILQDRAFQNEKIDFIWNHTVKQINEENGKVGSVTIVDVNTGEETEFKADGVFVYIG
HHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCEEEEEEEEECCCCCCEEECCCEEEEEE
MLPLSKPFAALGITNENGYIETNERMETKVPGIFAAGDIREKMLRQIVTATGDGSIAAQS
ECCCCCCCEEEEEECCCCEEECCCCHHHCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHH
VQHYVEELLEELNTVTEK
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]