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The map label for this gene is bdhA [H]

Identifier: 152977336

GI number: 152977336

Start: 3719458

End: 3720480

Strand: Reverse

Name: bdhA [H]

Synonym: Bcer98_3661

Alternate gene names: 152977336

Gene position: 3720480-3719458 (Counterclockwise)

Preceding gene: 152977337

Following gene: 152977335

Centisome position: 91.03

GC content: 37.73

Gene sequence:

>1023_bases
ATGAAGGCTGCAGTATGGTATGGTGAAAAAGATATTCGTATTGAGGAAAGAGAAGTGAAAGAATTACAACCCAATGATGT
GAAAGTTAAAGTAGCATGGACTGGTATTTGTGGTTCTGATTTACATGCATACTTGCATCCGGATTCAGTGCCAATGAATA
GGAATATGGTACTCGGACATGAGTTTTCTGGTGAAATTGTAGAGGTAGGTTCTCATGTTACGAAATTTAAAGAAGGTGAC
AGAGTATGTATCTATCCAATGATGCTTAAAGATCCTTCAAATGCTGAAATTGAACGTTTCATCACTTTAGACGCGGTTGG
AGCACAAATCGACGGAGGGTTTGCAGAATACGCGATACTTCCACAAAAAACGATTTTTAAAATTCCAGATACTTTACCAC
TAGAATTAGCAGCAATGGTAGAACCAGCAGCTGTATCTTTTCAATCAGTTAAGGATTCAAATGTAAAAGAAGGAGATACT
ATTGTTGTCTATGGCGCAGGTCCTATCGGGCTATTTGCTGTATTAGGGGCAAAAGCTGCAGGTGTTTCTAATATTATTGT
TGTCGATTTATTGGATAGTCGACTCGACAAAGCAACTGAATTGGGTGCAACACACGTCTTTAATGCTAGAGAAGTGAACC
CTGTTGAAGAAATTCGTAAATTATTCCCAGATGGAGCAGATGTTGTATTTGAAGCTGCAGGTGTTGAGTCAACATTTAAT
CAAGCCATTCAATCAACTAAAGTTCGTGGCACAATGATGGTTATCAGCTTTCACACCCAGGATATCCAATTTAATGCTCC
TTCATCCCTACTCTTTAGCGGCGTAAAATTAATGGGATCTGTGGGATATAGCAATGAAACTTATAACGAGGTCATTGAAT
TACTTGCTAATGGAAGATTACCGGCGCAATCAATTATTACAAGTAAAGTTGATATAGATAATATTGCTGAACAAGGCTTT
GAAGCATTAATTCATGATAAGTCTCAAGCAAAGATTCTAGTTAAATTAAGTGGCGCACATTAA

Upstream 100 bases:

>100_bases
GCAAAAGAAAATTGCTTTCATGTTTTAAAACATGAATTACAATCTAAAGTTACATGAAAAATTATATATAATATTTGAAT
GATTTAAAGGAGGATTTTTT

Downstream 100 bases:

>100_bases
TTATATTGTGGATAAATGAACTTGCGACGTGTAGAAAATTTCGTTCCTTGTTAATTAGATCTAGGCAGTAATGATAGGGC
GTATCCATAAAATAAGAGTG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Acetoin reductase/2,3-butanediol dehydrogenase; AR/BDH [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKAAVWYGEKDIRIEEREVKELQPNDVKVKVAWTGICGSDLHAYLHPDSVPMNRNMVLGHEFSGEIVEVGSHVTKFKEGD
RVCIYPMMLKDPSNAEIERFITLDAVGAQIDGGFAEYAILPQKTIFKIPDTLPLELAAMVEPAAVSFQSVKDSNVKEGDT
IVVYGAGPIGLFAVLGAKAAGVSNIIVVDLLDSRLDKATELGATHVFNAREVNPVEEIRKLFPDGADVVFEAAGVESTFN
QAIQSTKVRGTMMVISFHTQDIQFNAPSSLLFSGVKLMGSVGYSNETYNEVIELLANGRLPAQSIITSKVDIDNIAEQGF
EALIHDKSQAKILVKLSGAH

Sequences:

>Translated_340_residues
MKAAVWYGEKDIRIEEREVKELQPNDVKVKVAWTGICGSDLHAYLHPDSVPMNRNMVLGHEFSGEIVEVGSHVTKFKEGD
RVCIYPMMLKDPSNAEIERFITLDAVGAQIDGGFAEYAILPQKTIFKIPDTLPLELAAMVEPAAVSFQSVKDSNVKEGDT
IVVYGAGPIGLFAVLGAKAAGVSNIIVVDLLDSRLDKATELGATHVFNAREVNPVEEIRKLFPDGADVVFEAAGVESTFN
QAIQSTKVRGTMMVISFHTQDIQFNAPSSLLFSGVKLMGSVGYSNETYNEVIELLANGRLPAQSIITSKVDIDNIAEQGF
EALIHDKSQAKILVKLSGAH
>Mature_340_residues
MKAAVWYGEKDIRIEEREVKELQPNDVKVKVAWTGICGSDLHAYLHPDSVPMNRNMVLGHEFSGEIVEVGSHVTKFKEGD
RVCIYPMMLKDPSNAEIERFITLDAVGAQIDGGFAEYAILPQKTIFKIPDTLPLELAAMVEPAAVSFQSVKDSNVKEGDT
IVVYGAGPIGLFAVLGAKAAGVSNIIVVDLLDSRLDKATELGATHVFNAREVNPVEEIRKLFPDGADVVFEAAGVESTFN
QAIQSTKVRGTMMVISFHTQDIQFNAPSSLLFSGVKLMGSVGYSNETYNEVIELLANGRLPAQSIITSKVDIDNIAEQGF
EALIHDKSQAKILVKLSGAH

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=332, Percent_Identity=28.9156626506024, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI4501929, Length=370, Percent_Identity=27.8378378378378, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI156523966, Length=350, Percent_Identity=28.8571428571429, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI4501939, Length=350, Percent_Identity=28.8571428571429, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4501933, Length=370, Percent_Identity=27.8378378378378, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI34577061, Length=367, Percent_Identity=27.7929155313352, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI262073058, Length=370, Percent_Identity=27.2972972972973, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI71743840, Length=371, Percent_Identity=27.7628032345013, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI71565152, Length=378, Percent_Identity=25.3968253968254, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI71565154, Length=277, Percent_Identity=27.4368231046931, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI194239674, Length=177, Percent_Identity=29.3785310734463, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI13236495, Length=177, Percent_Identity=29.3785310734463, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788073, Length=337, Percent_Identity=32.3442136498516, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1790045, Length=341, Percent_Identity=30.4985337243402, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787863, Length=333, Percent_Identity=31.2312312312312, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788407, Length=338, Percent_Identity=27.5147928994083, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788075, Length=337, Percent_Identity=27.893175074184, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082125, Length=352, Percent_Identity=28.6931818181818, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI226510992, Length=336, Percent_Identity=25, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790718, Length=342, Percent_Identity=25.4385964912281, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786825, Length=394, Percent_Identity=23.3502538071066, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081918, Length=327, Percent_Identity=25.6880733944954, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994910, Length=359, Percent_Identity=28.4122562674095, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787572, Length=273, Percent_Identity=28.9377289377289, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=309, Percent_Identity=31.3915857605178, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17562878, Length=312, Percent_Identity=33.6538461538462, Blast_Score=147, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI25146526, Length=371, Percent_Identity=26.6846361185984, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71997431, Length=373, Percent_Identity=26.5415549597855, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988145, Length=339, Percent_Identity=26.8436578171091, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17565904, Length=341, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=301, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=301, Percent_Identity=26.2458471760797, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319955, Length=322, Percent_Identity=34.472049689441, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322619, Length=322, Percent_Identity=34.472049689441, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319257, Length=377, Percent_Identity=29.973474801061, Blast_Score=165, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6319258, Length=375, Percent_Identity=32.2666666666667, Blast_Score=162, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6323099, Length=325, Percent_Identity=32, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320033, Length=372, Percent_Identity=25, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=324, Percent_Identity=24.6913580246914, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=272, Percent_Identity=25.7352941176471, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=325, Percent_Identity=22.4615384615385, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=353, Percent_Identity=24.0793201133144, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319949, Length=254, Percent_Identity=27.5590551181102, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI17737897, Length=330, Percent_Identity=30.9090909090909, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17137530, Length=330, Percent_Identity=30.6060606060606, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17737895, Length=288, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221457811, Length=312, Percent_Identity=23.7179487179487, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45550770, Length=312, Percent_Identity=23.7179487179487, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45551930, Length=312, Percent_Identity=23.7179487179487, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.4 [H]

Molecular weight: Translated: 36947; Mature: 36947

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVWYGEKDIRIEEREVKELQPNDVKVKVAWTGICGSDLHAYLHPDSVPMNRNMVLGH
CCCEEEECCCCCEECHHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEE
EFSGEIVEVGSHVTKFKEGDRVCIYPMMLKDPSNAEIERFITLDAVGAQIDGGFAEYAIL
CCCCCHHHHCCHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEEEECCCEECCCEEEEEEC
PQKTIFKIPDTLPLELAAMVEPAAVSFQSVKDSNVKEGDTIVVYGAGPIGLFAVLGAKAA
CCCCEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCC
GVSNIIVVDLLDSRLDKATELGATHVFNAREVNPVEEIRKLFPDGADVVFEAAGVESTFN
CCCCEEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHH
QAIQSTKVRGTMMVISFHTQDIQFNAPSSLLFSGVKLMGSVGYSNETYNEVIELLANGRL
HHHHHHCCCEEEEEEEEEECEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
PAQSIITSKVDIDNIAEQGFEALIHDKSQAKILVKLSGAH
CHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
>Mature Secondary Structure
MKAAVWYGEKDIRIEEREVKELQPNDVKVKVAWTGICGSDLHAYLHPDSVPMNRNMVLGH
CCCEEEECCCCCEECHHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEE
EFSGEIVEVGSHVTKFKEGDRVCIYPMMLKDPSNAEIERFITLDAVGAQIDGGFAEYAIL
CCCCCHHHHCCHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEEEECCCEECCCEEEEEEC
PQKTIFKIPDTLPLELAAMVEPAAVSFQSVKDSNVKEGDTIVVYGAGPIGLFAVLGAKAA
CCCCEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCC
GVSNIIVVDLLDSRLDKATELGATHVFNAREVNPVEEIRKLFPDGADVVFEAAGVESTFN
CCCCEEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHH
QAIQSTKVRGTMMVISFHTQDIQFNAPSSLLFSGVKLMGSVGYSNETYNEVIELLANGRL
HHHHHHCCCEEEEEEEEEECEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
PAQSIITSKVDIDNIAEQGFEALIHDKSQAKILVKLSGAH
CHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]