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The map label for this gene is pheS [H]

Identifier: 152976946

GI number: 152976946

Start: 3316229

End: 3317263

Strand: Reverse

Name: pheS [H]

Synonym: Bcer98_3249

Alternate gene names: 152976946

Gene position: 3317263-3316229 (Counterclockwise)

Preceding gene: 152976947

Following gene: 152976945

Centisome position: 81.17

GC content: 39.03

Gene sequence:

>1035_bases
ATGGAAGCACGTTTAAAAGAGCTAAAGCAAAAAGCGTTAAAGCTTATTGAAGAAGCAAAAGAGCTAAAGAGTTTAAACGA
CGTACGCGTAGCGTATTTAGGTAAAAAAGGCCCGATTACAGAAGTATTACGCGGCATGGGGAAATTATCCCCAGAAGAGC
GTCCACGTATGGGAGCATTAGTAAATGAAGTGCGTGAAGCAATTCAAACTCGTCTAGAAGAAAAAGTGAGCAACTTAGAA
AAAGCAGTAATGGAAGCGAAACTAGCTTCTGAAACAATTGATGTTACACTGCCAGGTCGTCCTGTTGAAACAGGTTGTCA
CCATCCGTTAACAGCTGTTGTTGAACAAATTGAAGATGTATTTATCGGTATGGGTTATGAAGTAGCTGAAGGAACAGAAG
TAGAAAAAGACTACTACAATTTCGAAGCATTAAACTTACCGAAAGATCACCCAGCACGTGATATGCAAGATACATTCTAT
ATTACAGAAGAAACGTTACTACGTACACATACATCTTCTGTGCAAGCACGTACAATGGAAAACAATAAAGAAAAAGGTCC
GATTAAAATTATTTGTCCGGGTAAAGTATATCGCCGTGATGATGATGATGCGACACACTCACATCAGTTCATGCAAATTG
AAGGTCTTGTAATTGATAAAAATATTCGTATGAGTGATTTGAAAGGTACACTTCAAGTATTCGTGAAAAAGATGTTCGGT
GAAGATCGTGAAATTCGTCTTCGTCCAAGTTTCTTCCCATTCACAGAGCCATCTGTAGAGATGGATATTTCTTGTATGAT
GTGTCATGGTAAAGGTTGCGGCACTTGTAAAGGAACTGGCTGGATTGAAATTTTAGGCGCAGGTATGGTTCACCCGAACG
TACTTGAAATGGCTGGTTATGATTCAAAAGAATATCAAGGTTTTGCATTCGGTATGGGTGCAGAGCGTATCGCAATGTTG
AAATACGGCGTAGATGACATTCGTCATTTCTATACAAATGATGTACGTTTCTTACAACAATTCAAACGAGCGTAA

Upstream 100 bases:

>100_bases
TGGACAGACTTGTTCTGTCAATTTAGGGTGGTACCGCGAATTTACCTCGTCCCTTTTTGGGAGCGAGGTTTTTTTATTTT
TAAAATTAGGAGGGTTCCAA

Downstream 100 bases:

>100_bases
GGGAAGGAGAGGATAAGTATGTTCGTATCATATCGTTGGTTACAAGAGTATGTAGATATTAAAGATGTAACAGCACAAGA
GTTAGCAGACAAAATCACGA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MEARLKELKQKALKLIEEAKELKSLNDVRVAYLGKKGPITEVLRGMGKLSPEERPRMGALVNEVREAIQTRLEEKVSNLE
KAVMEAKLASETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFY
ITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFG
EDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAML
KYGVDDIRHFYTNDVRFLQQFKRA

Sequences:

>Translated_344_residues
MEARLKELKQKALKLIEEAKELKSLNDVRVAYLGKKGPITEVLRGMGKLSPEERPRMGALVNEVREAIQTRLEEKVSNLE
KAVMEAKLASETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFY
ITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFG
EDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAML
KYGVDDIRHFYTNDVRFLQQFKRA
>Mature_344_residues
MEARLKELKQKALKLIEEAKELKSLNDVRVAYLGKKGPITEVLRGMGKLSPEERPRMGALVNEVREAIQTRLEEKVSNLE
KAVMEAKLASETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFY
ITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFG
EDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAML
KYGVDDIRHFYTNDVRFLQQFKRA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=291, Percent_Identity=30.2405498281787, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI4758340, Length=276, Percent_Identity=28.9855072463768, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1788007, Length=340, Percent_Identity=50.5882352941176, Blast_Score=351, Evalue=5e-98,
Organism=Caenorhabditis elegans, GI17508957, Length=274, Percent_Identity=29.1970802919708, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32563657, Length=274, Percent_Identity=29.1970802919708, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32566635, Length=245, Percent_Identity=34.2857142857143, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321087, Length=272, Percent_Identity=30.1470588235294, Blast_Score=135, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6325304, Length=271, Percent_Identity=28.4132841328413, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI18858079, Length=274, Percent_Identity=30.6569343065693, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17137424, Length=293, Percent_Identity=26.962457337884, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 39050; Mature: 39050

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARLKELKQKALKLIEEAKELKSLNDVRVAYLGKKGPITEVLRGMGKLSPEERPRMGAL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHH
VNEVREAIQTRLEEKVSNLEKAVMEAKLASETIDVTLPGRPVETGCHHPLTAVVEQIEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
FIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTME
HHCCCEEECCCCCCHHHHCCCEEECCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHH
NNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFG
CCCCCCCEEEEECCHHCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHC
EDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGY
CCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHCCC
DSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
CCCCCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEARLKELKQKALKLIEEAKELKSLNDVRVAYLGKKGPITEVLRGMGKLSPEERPRMGAL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHH
VNEVREAIQTRLEEKVSNLEKAVMEAKLASETIDVTLPGRPVETGCHHPLTAVVEQIEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
FIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTME
HHCCCEEECCCCCCHHHHCCCEEECCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHH
NNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFG
CCCCCCCEEEEECCHHCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHC
EDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGY
CCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHCCC
DSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
CCCCCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA