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The map label for this gene is nadA

Identifier: 152976844

GI number: 152976844

Start: 3191915

End: 3193021

Strand: Reverse

Name: nadA

Synonym: Bcer98_3143

Alternate gene names: 152976844

Gene position: 3193021-3191915 (Counterclockwise)

Preceding gene: 152976845

Following gene: 152976843

Centisome position: 78.13

GC content: 38.3

Gene sequence:

>1107_bases
ATGAGTATTTTAGAAAAAGTACAGCCAATTGAAACGATGTTACCAGCGCGTTATTACACGATGTCAACGGAAGATATGGA
AAAGCGTGTTCGTGAAATTAAAGAAAAAATGGGAAAAATGTTATGTATCCCATGTCATCATTATCAAAAGGATGAAGTGG
TGCAGTTTTCAGATGCTATAGGGGATTCATTGCAACTTGCACAAGTTGCAGCGCGCAATAAAGAGGCAAAATATATCGTA
TTTTGCGGTGTGCATTTTATGGCAGAAACAGCGGATATGTTAACGACGGACGAGCAAGTTGTAATATTGCCTGATATGCG
AGCCGGCTGTTCGATGGCAGATATGGCGGATATTGAACAAACAGAACGAGCGTGGCGAGAGCTTACAACATTATTTGGAG
ATACAATGATTCCGTTAACATATGTAAACTCGACGGCAGCAATTAAAGCTTTTTGCGGTCGAAATGGCGGGGCAACCGTT
ACGTCTTCGAATGCAAAAAAAATGGTATCTTGGGCATTTACGCAGAAAGAACGATTAGTTTTTTTACCAGATCAGCATTT
GGGAAGAAATACAGCGTACGATTTAGGGATTGAACTTAATCAAATGGCTGTTTGGAATCCGAATACAGACTCATTAGAAT
ATAGCGGGAATCTAGAGGATATAAAGGTGATTTTGTGGAAAGGTCATTGTTCCGTGCATCAAAACTTTACAGTGAAGAAT
ATTGAGAGCTTGCGCAAAAGTCATCCTAATATGAATATTATCGTTCATCCAGAGTGTTGTTATGAAGTGGTTCAAGCTTC
TGATTATGCGGGATCGACAAAATATATTATTGATACGATTGAACAAGCACCATCTAGTAGTAAGTGGGCCATTGGTACAG
AAATGAATTTAGTAAATCGGCTGATTCAAAAACATTCTGATAAGGAGATTATTTCACTAAATCCTTTTATGTGTCCATGT
TTAACGATGAATCGTATTGATTTACCACATTTACTTTGGGCGCTAGAATCAATAGAACGTGGTGAACAGGTGAATGTAAT
TCAAGTGGATAAGCAAGTAACAAAAGATGCAGTGTTGGCATTAAATCGTATGTTAGAGCGCGTTTAA

Upstream 100 bases:

>100_bases
TTATATTTCACTTGGAGCATTAACGCATTCAGTGAAAGCACTCGATATTAGTTTCAATATTGAATCGTAAGAAAAGTGAC
TTAGAGGGAGAGAGACGTAT

Downstream 100 bases:

>100_bases
AAGTAGCGGGGTTCCCGTTGCTTTTTTCCTGCATATAATCATAATTATGAGGCAAATGACATACATTGTGTTGAGAGAAT
CATTGTGCTTTTTTTGTTTA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSILEKVQPIETMLPARYYTMSTEDMEKRVREIKEKMGKMLCIPCHHYQKDEVVQFSDAIGDSLQLAQVAARNKEAKYIV
FCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWRELTTLFGDTMIPLTYVNSTAAIKAFCGRNGGATV
TSSNAKKMVSWAFTQKERLVFLPDQHLGRNTAYDLGIELNQMAVWNPNTDSLEYSGNLEDIKVILWKGHCSVHQNFTVKN
IESLRKSHPNMNIIVHPECCYEVVQASDYAGSTKYIIDTIEQAPSSSKWAIGTEMNLVNRLIQKHSDKEIISLNPFMCPC
LTMNRIDLPHLLWALESIERGEQVNVIQVDKQVTKDAVLALNRMLERV

Sequences:

>Translated_368_residues
MSILEKVQPIETMLPARYYTMSTEDMEKRVREIKEKMGKMLCIPCHHYQKDEVVQFSDAIGDSLQLAQVAARNKEAKYIV
FCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWRELTTLFGDTMIPLTYVNSTAAIKAFCGRNGGATV
TSSNAKKMVSWAFTQKERLVFLPDQHLGRNTAYDLGIELNQMAVWNPNTDSLEYSGNLEDIKVILWKGHCSVHQNFTVKN
IESLRKSHPNMNIIVHPECCYEVVQASDYAGSTKYIIDTIEQAPSSSKWAIGTEMNLVNRLIQKHSDKEIISLNPFMCPC
LTMNRIDLPHLLWALESIERGEQVNVIQVDKQVTKDAVLALNRMLERV
>Mature_367_residues
SILEKVQPIETMLPARYYTMSTEDMEKRVREIKEKMGKMLCIPCHHYQKDEVVQFSDAIGDSLQLAQVAARNKEAKYIVF
CGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWRELTTLFGDTMIPLTYVNSTAAIKAFCGRNGGATVT
SSNAKKMVSWAFTQKERLVFLPDQHLGRNTAYDLGIELNQMAVWNPNTDSLEYSGNLEDIKVILWKGHCSVHQNFTVKNI
ESLRKSHPNMNIIVHPECCYEVVQASDYAGSTKYIIDTIEQAPSSSKWAIGTEMNLVNRLIQKHSDKEIISLNPFMCPCL
TMNRIDLPHLLWALESIERGEQVNVIQVDKQVTKDAVLALNRMLERV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=354, Percent_Identity=25.7062146892655, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_BACCN (A7GTA8)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376361.1
- ProteinModelPortal:   A7GTA8
- SMR:   A7GTA8
- STRING:   A7GTA8
- EnsemblBacteria:   EBBACT00000036098
- GeneID:   5344330
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_3143
- eggNOG:   COG0379
- GeneTree:   EBGT00050000002444
- HOGENOM:   HBG291157
- OMA:   GTELNLV
- ProtClustDB:   PRK09375
- BioCyc:   BCER315749:BCER98_3143-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00569
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 41733; Mature: 41601

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: BINDING 46-46 BINDING 63-63 BINDING 141-141 BINDING 162-162 BINDING 256-256 BINDING 273-273

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILEKVQPIETMLPARYYTMSTEDMEKRVREIKEKMGKMLCIPCHHYQKDEVVQFSDAI
CCHHHHHCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHC
GDSLQLAQVAARNKEAKYIVFCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQ
CCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TERAWRELTTLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKKMVSWAFTQKERLV
HHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCEE
FLPDQHLGRNTAYDLGIELNQMAVWNPNTDSLEYSGNLEDIKVILWKGHCSVHQNFTVKN
ECCCHHCCCCCEEECCEEECEEEEECCCCCCEEECCCCCEEEEEEEECCCCCCCCCCHHH
IESLRKSHPNMNIIVHPECCYEVVQASDYAGSTKYIIDTIEQAPSSSKWAIGTEMNLVNR
HHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCHHHHHHH
LIQKHSDKEIISLNPFMCPCLTMNRIDLPHLLWALESIERGEQVNVIQVDKQVTKDAVLA
HHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
LNRMLERV
HHHHHHCC
>Mature Secondary Structure 
SILEKVQPIETMLPARYYTMSTEDMEKRVREIKEKMGKMLCIPCHHYQKDEVVQFSDAI
CHHHHHCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHC
GDSLQLAQVAARNKEAKYIVFCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQ
CCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TERAWRELTTLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKKMVSWAFTQKERLV
HHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCEE
FLPDQHLGRNTAYDLGIELNQMAVWNPNTDSLEYSGNLEDIKVILWKGHCSVHQNFTVKN
ECCCHHCCCCCEEECCEEECEEEEECCCCCCEEECCCCCEEEEEEEECCCCCCCCCCHHH
IESLRKSHPNMNIIVHPECCYEVVQASDYAGSTKYIIDTIEQAPSSSKWAIGTEMNLVNR
HHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCHHHHHHH
LIQKHSDKEIISLNPFMCPCLTMNRIDLPHLLWALESIERGEQVNVIQVDKQVTKDAVLA
HHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
LNRMLERV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA