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The map label for this gene is dtd [H]

Identifier: 152976824

GI number: 152976824

Start: 3167606

End: 3168046

Strand: Reverse

Name: dtd [H]

Synonym: Bcer98_3122

Alternate gene names: 152976824

Gene position: 3168046-3167606 (Counterclockwise)

Preceding gene: 152976825

Following gene: 152976823

Centisome position: 77.51

GC content: 39.68

Gene sequence:

>441_bases
ATGAGAGTTGTCTTACAGCGATCAAAGGAAGCGTCCGTCACAGTAGATGGTGAGATTGTGGGACAAATTCCGTTTGGCTT
AACATTACTAGTTGGCATTACGCATGAAGATACAGAACAAGATGCAGCTTACATTGCTGAAAAAATTGCGAACTTACGTA
TTTTTGAAGATGAGAACGGCAAAATGAACCATTCTATACTCGATGTAAAAGGACAAGTTTTATCCATCTCGCAATTTACA
TTATACGGGGATTGTCGTAAAGGAAGACGCCCAAACTTTATGAATGCTGCGAAACCTGACTATGCAGAGCGCTTATACGA
TTTCTTTAACGAAGAAATTCGTAAACAAGGGCTGCACGTAGAAACAGGTAAATTCGGAGCAATGATGGACGTTTCTTTAG
TAAACGATGGTCCGGTGACCTTAATTGTAGAAAGTAAATAG

Upstream 100 bases:

>100_bases
GTAACTTACAACATTTGAAAAAGGTAGTAGAGCGTATTAAACAAGTTCCAGAAATTTATGCAGTACGCCGTATGATGCAT
TAATAGGGAGTGTATAACAT

Downstream 100 bases:

>100_bases
TGTTTTGGAAGAAGAGAGGAGTATGTGAGCCTCTCTTTTTTTATAATTTCTTTTAATGGTATATTTTTCTAATTATTGTT
ATGATATTTGTGAAAATACA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEQDAAYIAEKIANLRIFEDENGKMNHSILDVKGQVLSISQFT
LYGDCRKGRRPNFMNAAKPDYAERLYDFFNEEIRKQGLHVETGKFGAMMDVSLVNDGPVTLIVESK

Sequences:

>Translated_146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEQDAAYIAEKIANLRIFEDENGKMNHSILDVKGQVLSISQFT
LYGDCRKGRRPNFMNAAKPDYAERLYDFFNEEIRKQGLHVETGKFGAMMDVSLVNDGPVTLIVESK
>Mature_146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEQDAAYIAEKIANLRIFEDENGKMNHSILDVKGQVLSISQFT
LYGDCRKGRRPNFMNAAKPDYAERLYDFFNEEIRKQGLHVETGKFGAMMDVSLVNDGPVTLIVESK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=44.2953020134228, Blast_Score=116, Evalue=8e-27,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=47.9166666666667, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=46.9798657718121, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.2162162162162, Blast_Score=116, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=43.5374149659864, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16351; Mature: 16351

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEQDAAYIAEKIANLRIFEDENG
CCEEEECCCCCEEEECCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCC
KMNHSILDVKGQVLSISQFTLYGDCRKGRRPNFMNAAKPDYAERLYDFFNEEIRKQGLHV
CCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGKFGAMMDVSLVNDGPVTLIVESK
ECCCCCCEEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEQDAAYIAEKIANLRIFEDENG
CCEEEECCCCCEEEECCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCC
KMNHSILDVKGQVLSISQFTLYGDCRKGRRPNFMNAAKPDYAERLYDFFNEEIRKQGLHV
CCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGKFGAMMDVSLVNDGPVTLIVESK
ECCCCCCEEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA