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The map label for this gene is cymR [H]

Identifier: 152976812

GI number: 152976812

Start: 3151616

End: 3152032

Strand: Reverse

Name: cymR [H]

Synonym: Bcer98_3110

Alternate gene names: 152976812

Gene position: 3152032-3151616 (Counterclockwise)

Preceding gene: 152976814

Following gene: 152976811

Centisome position: 77.12

GC content: 40.53

Gene sequence:

>417_bases
ATGAAAATTTCAACAAAAGGCCGCTATGGTTTAACGATTATGATCGATCTTGCGAAAAAGTTTGGTGAAGGACCGATTTC
ATTAAAATCAATTGCTAAAGCGCACGATTTATCTGAGCATTATTTAGAGCAATTAATTTCCCCGCTTCGCAATGCTCGTC
TTGTAAAAAGTACGCGCGGGGCATATGGTGGTTATGTATTGTCTGATCAACCAGCTAATATAACGGCAGGCGATGTAATT
CGTGTGTTGGAAGGGCCAATTAGCGTCGTTGAGATGCTAGAGGAGGAAGAGCCCGCACAGCGTCAACTATGGATGCGTGT
TCGTGATGCAGTACAAGAAGTATTAGATAGTACAACATTGGAAGATTTAGTACGCTATGAGGAAGAAAATAATGGGGGTT
ATATGTTTTACATTTAA

Upstream 100 bases:

>100_bases
CTATATTATGCTATAATTTCATAGGATTTTAAATTGTGTTCTTTTGATAAATAAGCGATAACCAAATAGAAGTGACATTT
TGAAAAGAGGTGCGAAATAG

Downstream 100 bases:

>100_bases
TTCCTTGTGAAACGATTTGGAAAGAAGGAGATTGAATGGAACGCATTTACTTAGATCATGCAGCAACATCTAAAGTTCAT
CCAGAAGTGGTCGAAAAGAT

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAKAHDLSEHYLEQLISPLRNARLVKSTRGAYGGYVLSDQPANITAGDVI
RVLEGPISVVEMLEEEEPAQRQLWMRVRDAVQEVLDSTTLEDLVRYEEENNGGYMFYI

Sequences:

>Translated_138_residues
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAKAHDLSEHYLEQLISPLRNARLVKSTRGAYGGYVLSDQPANITAGDVI
RVLEGPISVVEMLEEEEPAQRQLWMRVRDAVQEVLDSTTLEDLVRYEEENNGGYMFYI
>Mature_138_residues
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAKAHDLSEHYLEQLISPLRNARLVKSTRGAYGGYVLSDQPANITAGDVI
RVLEGPISVVEMLEEEEPAQRQLWMRVRDAVQEVLDSTTLEDLVRYEEENNGGYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=32.8358208955224, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15548; Mature: 15548

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAKAHDLSEHYLEQLISPLRNARLVKSTRG
CCCCCCCCCCHHHHEEHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCC
AYGGYVLSDQPANITAGDVIRVLEGPISVVEMLEEEEPAQRQLWMRVRDAVQEVLDSTTL
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHH
EDLVRYEEENNGGYMFYI
HHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAKAHDLSEHYLEQLISPLRNARLVKSTRG
CCCCCCCCCCHHHHEEHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCC
AYGGYVLSDQPANITAGDVIRVLEGPISVVEMLEEEEPAQRQLWMRVRDAVQEVLDSTTL
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHH
EDLVRYEEENNGGYMFYI
HHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]