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The map label for this gene is aroE

Identifier: 152976764

GI number: 152976764

Start: 3105557

End: 3106390

Strand: Reverse

Name: aroE

Synonym: Bcer98_3060

Alternate gene names: 152976764

Gene position: 3106390-3105557 (Counterclockwise)

Preceding gene: 152976765

Following gene: 152976763

Centisome position: 76.01

GC content: 38.73

Gene sequence:

>834_bases
ATGAAACAATTATATGGTGTAATCGGAAATCCAATTGGACATTCCTTATCACCGCTTATGCATAATGATGCGTTTGAACA
TTTAGGAATAGATGCTCATTATCATGCGTTTCTTGTAGAAGAAGAGATGCTAGGGGAAGCTGTGAAAGGGTTAAAGGCGT
TAGGAGTTTCAGGGATCAATGTAACGACTCCACATAAAGTTGCTATTATGAAATATTTAGATGAAATCGATCCGTTAGCA
AAGCAAATCGGTGCAGTAAATACTGTTGTTCATCGAAACGGCAAGCTTGTTGGTTATAATACAGATGGAATTGGGTATGT
TCGTTCTTTGCAGGCTATTAGTAAAGAACCCTTACGTCACAAACGTATGTTATTACTCGGTGCAGGTGGTGCATGTCGTG
CTATTTATTGTTCGCTAGTAGCTGCAGGAGTAAAAGAAATCGATATTGCCAACCGGACGGTAGAAACAGCAAAGCAGTTG
ATTGCAAGTAGCAAAGAACGGGTTGTTTCAAAGGCGCTTTCACTAGAGAAAGCGACGGAAGCACAAGAGAATTATGATGT
GCTGATTCAAACGACAACGATAGGTATGCATCCACATGTACAACATACGCCAATGCAAATTGGCTCTTTAAAACAAGGGG
CAATTGTTTCTGATATTATTTATAATCCTTTTGAAACGAAGTTCTTACATGATGCAAAATTGAGTGGAGCGATTGTTCAA
AACGGTATTGATATGTTTGTTTATCAAGGGGCACTTGCCTTTGAGATGTGGACTGGAATGATGCCAGACATTAATAGAAT
GAAACAATTAGTAATAAGAAAGCTTGGAGGATAA

Upstream 100 bases:

>100_bases
GGGTTACTGTGAACGAACCAGGAGCAAAAATTGTTGCTCATATACCAAAAGGAGTTAGTGTTTCATTACGTAAATCTTTA
ATTTAAATGGAGAGGGATTT

Downstream 100 bases:

>100_bases
TGATATGTTAACAGGAAAACAAAAAAGATTTTTACGTGCAAAGGCGCATCATTTAACACCGATTTTTCAAGTAGGAAAAG
GTGGCGTAAATGAAAATATG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKQLYGVIGNPIGHSLSPLMHNDAFEHLGIDAHYHAFLVEEEMLGEAVKGLKALGVSGINVTTPHKVAIMKYLDEIDPLA
KQIGAVNTVVHRNGKLVGYNTDGIGYVRSLQAISKEPLRHKRMLLLGAGGACRAIYCSLVAAGVKEIDIANRTVETAKQL
IASSKERVVSKALSLEKATEAQENYDVLIQTTTIGMHPHVQHTPMQIGSLKQGAIVSDIIYNPFETKFLHDAKLSGAIVQ
NGIDMFVYQGALAFEMWTGMMPDINRMKQLVIRKLGG

Sequences:

>Translated_277_residues
MKQLYGVIGNPIGHSLSPLMHNDAFEHLGIDAHYHAFLVEEEMLGEAVKGLKALGVSGINVTTPHKVAIMKYLDEIDPLA
KQIGAVNTVVHRNGKLVGYNTDGIGYVRSLQAISKEPLRHKRMLLLGAGGACRAIYCSLVAAGVKEIDIANRTVETAKQL
IASSKERVVSKALSLEKATEAQENYDVLIQTTTIGMHPHVQHTPMQIGSLKQGAIVSDIIYNPFETKFLHDAKLSGAIVQ
NGIDMFVYQGALAFEMWTGMMPDINRMKQLVIRKLGG
>Mature_277_residues
MKQLYGVIGNPIGHSLSPLMHNDAFEHLGIDAHYHAFLVEEEMLGEAVKGLKALGVSGINVTTPHKVAIMKYLDEIDPLA
KQIGAVNTVVHRNGKLVGYNTDGIGYVRSLQAISKEPLRHKRMLLLGAGGACRAIYCSLVAAGVKEIDIANRTVETAKQL
IASSKERVVSKALSLEKATEAQENYDVLIQTTTIGMHPHVQHTPMQIGSLKQGAIVSDIIYNPFETKFLHDAKLSGAIVQ
NGIDMFVYQGALAFEMWTGMMPDINRMKQLVIRKLGG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1787983, Length=279, Percent_Identity=36.9175627240143, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1789675, Length=272, Percent_Identity=32.7205882352941, Blast_Score=120, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6320332, Length=272, Percent_Identity=34.1911764705882, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROE_BACCN (A7GT28)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376281.1
- ProteinModelPortal:   A7GT28
- SMR:   A7GT28
- STRING:   A7GT28
- EnsemblBacteria:   EBBACT00000037551
- GeneID:   5346628
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_3060
- eggNOG:   COG0169
- GeneTree:   EBGT00050000000826
- HOGENOM:   HBG553408
- OMA:   GMHPRVE
- ProtClustDB:   PRK00258
- BioCyc:   BCER315749:BCER98_3060-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00222
- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR00507

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N

EC number: =1.1.1.25

Molecular weight: Translated: 30239; Mature: 30239

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: ACT_SITE 66-66

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLYGVIGNPIGHSLSPLMHNDAFEHLGIDAHYHAFLVEEEMLGEAVKGLKALGVSGIN
CCCHHHHHCCCCCCCCCHHHHCCHHHHCCCCCHHHHEEHHHHHHHHHHHHHHHHCCCCCC
VTTPHKVAIMKYLDEIDPLAKQIGAVNTVVHRNGKLVGYNTDGIGYVRSLQAISKEPLRH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHHHCHHHH
KRMLLLGAGGACRAIYCSLVAAGVKEIDIANRTVETAKQLIASSKERVVSKALSLEKATE
HEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQENYDVLIQTTTIGMHPHVQHTPMQIGSLKQGAIVSDIIYNPFETKFLHDAKLSGAIVQ
CCCCCEEEEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCCHHHH
NGIDMFVYQGALAFEMWTGMMPDINRMKQLVIRKLGG
CCCCEEHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQLYGVIGNPIGHSLSPLMHNDAFEHLGIDAHYHAFLVEEEMLGEAVKGLKALGVSGIN
CCCHHHHHCCCCCCCCCHHHHCCHHHHCCCCCHHHHEEHHHHHHHHHHHHHHHHCCCCCC
VTTPHKVAIMKYLDEIDPLAKQIGAVNTVVHRNGKLVGYNTDGIGYVRSLQAISKEPLRH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHHHCHHHH
KRMLLLGAGGACRAIYCSLVAAGVKEIDIANRTVETAKQLIASSKERVVSKALSLEKATE
HEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQENYDVLIQTTTIGMHPHVQHTPMQIGSLKQGAIVSDIIYNPFETKFLHDAKLSGAIVQ
CCCCCEEEEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCCHHHH
NGIDMFVYQGALAFEMWTGMMPDINRMKQLVIRKLGG
CCCCEEHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA