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The map label for this gene is dppE [H]

Identifier: 152974036

GI number: 152974036

Start: 200876

End: 202477

Strand: Direct

Name: dppE [H]

Synonym: Bcer98_0190

Alternate gene names: 152974036

Gene position: 200876-202477 (Clockwise)

Preceding gene: 152974035

Following gene: 152974038

Centisome position: 4.91

GC content: 33.15

Gene sequence:

>1602_bases
ATGAAGAAGATTTTACTTTTTGCCATTATGACAGTTTTAGCGATTGCTTCTGTCGGCTGCGGTAAGAAAGAAGCGTCAAA
GGCAAGTGCAGATAAGGGGGATCGCTTAGTCACAAATATTAGTAGTGACCCATATACACTTGATTCAGCAATTGCGACAG
ATAGTACGTCAGGTTATGTAATTGAACATTTATTTAGTGGTCTATATACAAAGGATGCGAATGGAAAATATCAAAATGAG
TTGGCAGAGAAAGAAGAAGTAAATGTAGATGGAACAGAATATACAATTCATTTAAAGAAAGATATGAAATGGTCAGATGG
TTCACCTATTACGGCTAATGATTTTGAATTTGCATGGAAGCGTATATTAAATCCTAAAACAGGCTCTATGAATGCAACAG
AAATGTATTTTATTAAGGGTGCAGAAGCGTATAATACTGGAAAAGGTGAAGAAGGACAAGTAGGTATTCAAGCGGTAGAT
TCGCAAACTTTAAAAGTAACGCTTGAACATCCAGTTGCATCTATCAAACAACAATTAGCGAATTCTTTATTTATTCCACT
TTCAAAAAAATCTATCGATGATAAAAATAAGTTAAAAACAAGTCCAAAAGAATTACTTACAAACGGACCGTTCAAATTAA
AAGAGTGGAAGCATAACCAAGCAATTATTTTAGAGAAGAACAAAGAGTTTCATGATAAAAAAGTAACATTAAAAGAATTG
GAGTTTCGTATTATTCCAGATACTAATACGGCATATCAATTGTATAAATCGAAAGAACTAGACTTATTAAGCGGCTTGCC
ACAAGAGATGGTTGAAAAAGAAAAAAGAAATAAAGAATATAAACGTATGGCAGGATTTTCATCTTATATTTATTCATTTA
ATGTTGAAAAAGAACCGTTTACCAATGCGAAAATACGAAAAGCATTTGCGTTAGCACTTGATCGTAAATTTATTGTTGAA
AAATTGTATAAAGGGAATGCACAAGAAGCATATGCTTTTGTTCCAGAAGGAGCGAAAACACAGAGTGGCCGTGATTTCCG
TAAAGAAAAAGGGGATTATTTAAAATTTGACCCAGTAGAAGCGAAAAAATTATTAGAAGAAGGCATGAAAGAACAAGGAT
GGACAGAGCTTCCTCAAGTAACATTGAAGTATACAACAGATACACAACATAAAAAAGTAGCAGAAGCAATGCAAGAAATG
TTCAAGAAAAATCTTGGTGTGGATGTAAAACTAGAAAATAAAGAGTGGAAAAGTTACATTGATACGTATAAACAAAGTGA
CTTTCAATTAGCTTATATGGGATGGGGCGGAGCTGTAGATCCAATTAAAAAACTTGAATTATATGCAGGTGATGGACCGA
ATAACTATGCAAAATGGCATAATAAAGAATTTGATACTTTAATAAAAGAAGCGGAAGTTGAAAGAGATGAAGAAAAGCGC
TTTGATTTGTTGCATAAAGCAGAAGATATTATGTTTGCTGAAACGCCATTAATCCCAATCTTATTCCCATCATCATCCTA
TTTACAAAAAGAATCAGTGTCTGGGGTTCAGTATGATGTTGAAGGTAAACCAGATTTACGTTATGTAAAAATCAAGAAAT
AA

Upstream 100 bases:

>100_bases
TTTGGAGATACGGATGAAGTATTCCGTAATCCACAACATTCTTATACAAAAACATTGTTAGAATCGACACCAAAAATTTC
AGGCTAAAGGAGAATGTAGA

Downstream 100 bases:

>100_bases
TACAAAATAAAGAAGTAGGCATTTGCCTACTTCTTTATTTTGCTTCCTTCTTATATTCTTTCTTCGTTCCATCAGAGAAG
ACAACTTCTAATTCGAATTT

Product: extracellular solute-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MKKILLFAIMTVLAIASVGCGKKEASKASADKGDRLVTNISSDPYTLDSAIATDSTSGYVIEHLFSGLYTKDANGKYQNE
LAEKEEVNVDGTEYTIHLKKDMKWSDGSPITANDFEFAWKRILNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQAVD
SQTLKVTLEHPVASIKQQLANSLFIPLSKKSIDDKNKLKTSPKELLTNGPFKLKEWKHNQAIILEKNKEFHDKKVTLKEL
EFRIIPDTNTAYQLYKSKELDLLSGLPQEMVEKEKRNKEYKRMAGFSSYIYSFNVEKEPFTNAKIRKAFALALDRKFIVE
KLYKGNAQEAYAFVPEGAKTQSGRDFRKEKGDYLKFDPVEAKKLLEEGMKEQGWTELPQVTLKYTTDTQHKKVAEAMQEM
FKKNLGVDVKLENKEWKSYIDTYKQSDFQLAYMGWGGAVDPIKKLELYAGDGPNNYAKWHNKEFDTLIKEAEVERDEEKR
FDLLHKAEDIMFAETPLIPILFPSSSYLQKESVSGVQYDVEGKPDLRYVKIKK

Sequences:

>Translated_533_residues
MKKILLFAIMTVLAIASVGCGKKEASKASADKGDRLVTNISSDPYTLDSAIATDSTSGYVIEHLFSGLYTKDANGKYQNE
LAEKEEVNVDGTEYTIHLKKDMKWSDGSPITANDFEFAWKRILNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQAVD
SQTLKVTLEHPVASIKQQLANSLFIPLSKKSIDDKNKLKTSPKELLTNGPFKLKEWKHNQAIILEKNKEFHDKKVTLKEL
EFRIIPDTNTAYQLYKSKELDLLSGLPQEMVEKEKRNKEYKRMAGFSSYIYSFNVEKEPFTNAKIRKAFALALDRKFIVE
KLYKGNAQEAYAFVPEGAKTQSGRDFRKEKGDYLKFDPVEAKKLLEEGMKEQGWTELPQVTLKYTTDTQHKKVAEAMQEM
FKKNLGVDVKLENKEWKSYIDTYKQSDFQLAYMGWGGAVDPIKKLELYAGDGPNNYAKWHNKEFDTLIKEAEVERDEEKR
FDLLHKAEDIMFAETPLIPILFPSSSYLQKESVSGVQYDVEGKPDLRYVKIKK
>Mature_533_residues
MKKILLFAIMTVLAIASVGCGKKEASKASADKGDRLVTNISSDPYTLDSAIATDSTSGYVIEHLFSGLYTKDANGKYQNE
LAEKEEVNVDGTEYTIHLKKDMKWSDGSPITANDFEFAWKRILNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQAVD
SQTLKVTLEHPVASIKQQLANSLFIPLSKKSIDDKNKLKTSPKELLTNGPFKLKEWKHNQAIILEKNKEFHDKKVTLKEL
EFRIIPDTNTAYQLYKSKELDLLSGLPQEMVEKEKRNKEYKRMAGFSSYIYSFNVEKEPFTNAKIRKAFALALDRKFIVE
KLYKGNAQEAYAFVPEGAKTQSGRDFRKEKGDYLKFDPVEAKKLLEEGMKEQGWTELPQVTLKYTTDTQHKKVAEAMQEM
FKKNLGVDVKLENKEWKSYIDTYKQSDFQLAYMGWGGAVDPIKKLELYAGDGPNNYAKWHNKEFDTLIKEAEVERDEEKR
FDLLHKAEDIMFAETPLIPILFPSSSYLQKESVSGVQYDVEGKPDLRYVKIKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=528, Percent_Identity=30.3030303030303, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1789397, Length=484, Percent_Identity=31.8181818181818, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI87081878, Length=534, Percent_Identity=29.5880149812734, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1789966, Length=471, Percent_Identity=27.6008492569002, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787052, Length=502, Percent_Identity=25.4980079681275, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787762, Length=486, Percent_Identity=25.1028806584362, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787551, Length=555, Percent_Identity=20.9009009009009, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789887, Length=404, Percent_Identity=23.7623762376238, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60780; Mature: 60780

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLFAIMTVLAIASVGCGKKEASKASADKGDRLVTNISSDPYTLDSAIATDSTSGYV
CCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEECCCCCEECCHHHCCCCCCCHH
IEHLFSGLYTKDANGKYQNELAEKEEVNVDGTEYTIHLKKDMKWSDGSPITANDFEFAWK
HHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHH
RILNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQAVDSQTLKVTLEHPVASIKQQLA
HHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHHH
NSLFIPLSKKSIDDKNKLKTSPKELLTNGPFKLKEWKHNQAIILEKNKEFHDKKVTLKEL
HHEEEECCCCCCCCHHHHCCCHHHHHCCCCCEEEECCCCCEEEEECCCCCCCHHCEEEHE
EFRIIPDTNTAYQLYKSKELDLLSGLPQEMVEKEKRNKEYKRMAGFSSYIYSFNVEKEPF
EEEEECCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCC
TNAKIRKAFALALDRKFIVEKLYKGNAQEAYAFVPEGAKTQSGRDFRKEKGDYLKFDPVE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECCHH
AKKLLEEGMKEQGWTELPQVTLKYTTDTQHKKVAEAMQEMFKKNLGVDVKLENKEWKSYI
HHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHH
DTYKQSDFQLAYMGWGGAVDPIKKLELYAGDGPNNYAKWHNKEFDTLIKEAEVERDEEKR
HHHCCCCCEEEEECCCCCCCCHHHEEEEECCCCCCCHHCCCCHHHHHHHHHHCCCCHHHH
FDLLHKAEDIMFAETPLIPILFPSSSYLQKESVSGVQYDVEGKPDLRYVKIKK
HHHHHHHHHHEEECCCEEEEEECCCHHHHHHCCCCCEEECCCCCCEEEEEEEC
>Mature Secondary Structure
MKKILLFAIMTVLAIASVGCGKKEASKASADKGDRLVTNISSDPYTLDSAIATDSTSGYV
CCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEECCCCCEECCHHHCCCCCCCHH
IEHLFSGLYTKDANGKYQNELAEKEEVNVDGTEYTIHLKKDMKWSDGSPITANDFEFAWK
HHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHH
RILNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQAVDSQTLKVTLEHPVASIKQQLA
HHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHHH
NSLFIPLSKKSIDDKNKLKTSPKELLTNGPFKLKEWKHNQAIILEKNKEFHDKKVTLKEL
HHEEEECCCCCCCCHHHHCCCHHHHHCCCCCEEEECCCCCEEEEECCCCCCCHHCEEEHE
EFRIIPDTNTAYQLYKSKELDLLSGLPQEMVEKEKRNKEYKRMAGFSSYIYSFNVEKEPF
EEEEECCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCC
TNAKIRKAFALALDRKFIVEKLYKGNAQEAYAFVPEGAKTQSGRDFRKEKGDYLKFDPVE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECCHH
AKKLLEEGMKEQGWTELPQVTLKYTTDTQHKKVAEAMQEMFKKNLGVDVKLENKEWKSYI
HHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHH
DTYKQSDFQLAYMGWGGAVDPIKKLELYAGDGPNNYAKWHNKEFDTLIKEAEVERDEEKR
HHHCCCCCEEEEECCCCCCCCHHHEEEEECCCCCCCHHCCCCHHHHHHHHHHCCCCHHHH
FDLLHKAEDIMFAETPLIPILFPSSSYLQKESVSGVQYDVEGKPDLRYVKIKK
HHHHHHHHHHEEECCCEEEEEECCCHHHHHHCCCCCEEECCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]