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The map label for this gene is glmS [H]

Identifier: 152974003

GI number: 152974003

Start: 164263

End: 166131

Strand: Direct

Name: glmS [H]

Synonym: Bcer98_0152

Alternate gene names: 152974003

Gene position: 164263-166131 (Clockwise)

Preceding gene: 152974002

Following gene: 152974004

Centisome position: 4.02

GC content: 38.68

Gene sequence:

>1869_bases
ATGAGATTGGACGAGGTCGTTACATGTTCGCAGGGCAATGTAAGCATTTGTAACGGCGACTTAAACATGTGTGGAATTGT
AGGATTTATTGGAGAGAAAGATGCAAAGGAAATTTTATTAAAAGGTTTAGAGAAGCTAGAATACCGTGGATATGATTCAG
CAGGTATTGCAGTACAGACAGAGAACGGTGTTGTTGTGTACAAAGAAAAAGGTCGTATTGCAAAACTTCGTGAAATCGTA
GATGAAAATGTAGCAACAAGCGTGGGAATCGGTCATACACGTTGGGCAACACATGGTGTTCCAAGTAAAGTAAATGCGCA
TCCGCATCAAAGTACATCAAAACGCTTTACGCTAGTTCATAATGGTGTAATTGAAAACTATGAATTAGTGAAGAACGAAT
ATTTACAAGATGTAACGTTTGTAAGTGAAACAGATACAGAAGTTATCGTTCAACTTATTGAACAACAAGTAAATACAGGT
TTAAATGTAGAAGAGGCGTTCCGTAAAGTTTTATCTCTTTTACATGGTTCTTATGCAATTGGTTTACTTGATGCTGAAAA
TCCAAACATGATTTATGTTGCTAAAAACAAAAGCCCGCTATTAGTAGGTGTTGGCGACAACTTTAAAGTTGTTGCGAGCG
ATGCAATGGCGATGTTACAAGTTACAGATCAATTTATCGAATTAATGGATAAAGAAGTCGTAATCGTAACAAAAGAAAGC
ATTACAATTAAAAACTTACAAGGTGAAACGATTGAACGTGCGCCATTTACAGCGGAATTAGATGCAAGTGATATTGAAAA
AGGAACATATCCTCACTTCATGCTGAAAGAAATTGATGAGCAACCACTTGTAATCCGTAATATTATTCAAAAGTATCAAG
ATGAAAATGGCGAGATTGAATTAGATGAAGAGATTCGCAGTGCTATTTTAGCGAGCGATCGCATTTATATCATTGCATGT
GGCACAAGTTATCATGCAGGTCTTGTTGGAAAGCAATTTATTGAGAAATTTGCAAAAGTACCTGTAGAAGTGCATGTCGC
AAGTGAATTCTCGTATAATATGCCACTATTAACAGAAAAACCTTTCTTCATTTACATTTCACAAAGTGGTGAAACAGCAG
ATAGCCGTGCCGTACTTGTGCAAACAAATGAAATGGGTCATAAAGCATTAACAATCACAAATGTACCAGGTTCAACACTT
TCTCGTGAAGCTGATTACACGCTTCCTTTATATGCGGGGCCTGAAATCGCAGTTGCTTCTACAAAAGCATATACAGCACA
ACTTGCCGTACTTGCAATCTTAGCAGCTGACATTGCAAAAGCAAAAGGTGAAGTTCTTGATTTTGACTTAACACACGAAT
TAGGACTTGTAGCAAATGCAATGGAAGTACTTTGTGATCAAAAAGAAGAAATGGATGCACTGGCAAAACAATTCCTAGCA
ACAACACGCAACTGTTTCTTTATCGGACGTAGCGTAGACTTCTATGTAGGTTTAGAAGGGGCGTTAAAGCTAAAAGAAAT
CTCTTACATCCAAGCTGAAGGATTTGCTGGAGGAGAGTTAAAGCATGGTACAATTGCGTTAATTGAAAAAGGTACACCAG
TTATCGCACTTGCTACACAAGAGCACGTAAACCTAGGAATTCGTGGTAACGTAAAAGAAGTAGTAGCGCGCGGTGCAAAC
CCATGCATCATCTCTATGAAAGGCTTAGAAATGGAAGGCGACAGCTTCGTACTACCAGCTGTACACGAAGCACTAGCACC
ACTTGTAGCCGTAGTTCCATTACAACTGATCTCATACTACGCAGCACTTCACCGCGAGTGTGACGTTGATAAGCCGCGTA
ACTTAGCTAAATCTGTTACTGTTGAGTAA

Upstream 100 bases:

>100_bases
GTATAAATGTTATACGGACTGGAAACCAATCGAGAGGAAGGTGAAAGCCGTTACAGATTTACAGAGCTAGCAATATGTAA
TCCGTTTTTTATGAAAAATA

Downstream 100 bases:

>100_bases
GGGATTGGAGAGTTAGTGTTTGTTGTGTTGATTTGTAAAAAAGATTAATCATTTGAAACAAAGTTCGGTTATTTAAAATA
TAGATTGATAATTTATAATA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MRLDEVVTCSQGNVSICNGDLNMCGIVGFIGEKDAKEILLKGLEKLEYRGYDSAGIAVQTENGVVVYKEKGRIAKLREIV
DENVATSVGIGHTRWATHGVPSKVNAHPHQSTSKRFTLVHNGVIENYELVKNEYLQDVTFVSETDTEVIVQLIEQQVNTG
LNVEEAFRKVLSLLHGSYAIGLLDAENPNMIYVAKNKSPLLVGVGDNFKVVASDAMAMLQVTDQFIELMDKEVVIVTKES
ITIKNLQGETIERAPFTAELDASDIEKGTYPHFMLKEIDEQPLVIRNIIQKYQDENGEIELDEEIRSAILASDRIYIIAC
GTSYHAGLVGKQFIEKFAKVPVEVHVASEFSYNMPLLTEKPFFIYISQSGETADSRAVLVQTNEMGHKALTITNVPGSTL
SREADYTLPLYAGPEIAVASTKAYTAQLAVLAILAADIAKAKGEVLDFDLTHELGLVANAMEVLCDQKEEMDALAKQFLA
TTRNCFFIGRSVDFYVGLEGALKLKEISYIQAEGFAGGELKHGTIALIEKGTPVIALATQEHVNLGIRGNVKEVVARGAN
PCIISMKGLEMEGDSFVLPAVHEALAPLVAVVPLQLISYYAALHRECDVDKPRNLAKSVTVE

Sequences:

>Translated_622_residues
MRLDEVVTCSQGNVSICNGDLNMCGIVGFIGEKDAKEILLKGLEKLEYRGYDSAGIAVQTENGVVVYKEKGRIAKLREIV
DENVATSVGIGHTRWATHGVPSKVNAHPHQSTSKRFTLVHNGVIENYELVKNEYLQDVTFVSETDTEVIVQLIEQQVNTG
LNVEEAFRKVLSLLHGSYAIGLLDAENPNMIYVAKNKSPLLVGVGDNFKVVASDAMAMLQVTDQFIELMDKEVVIVTKES
ITIKNLQGETIERAPFTAELDASDIEKGTYPHFMLKEIDEQPLVIRNIIQKYQDENGEIELDEEIRSAILASDRIYIIAC
GTSYHAGLVGKQFIEKFAKVPVEVHVASEFSYNMPLLTEKPFFIYISQSGETADSRAVLVQTNEMGHKALTITNVPGSTL
SREADYTLPLYAGPEIAVASTKAYTAQLAVLAILAADIAKAKGEVLDFDLTHELGLVANAMEVLCDQKEEMDALAKQFLA
TTRNCFFIGRSVDFYVGLEGALKLKEISYIQAEGFAGGELKHGTIALIEKGTPVIALATQEHVNLGIRGNVKEVVARGAN
PCIISMKGLEMEGDSFVLPAVHEALAPLVAVVPLQLISYYAALHRECDVDKPRNLAKSVTVE
>Mature_622_residues
MRLDEVVTCSQGNVSICNGDLNMCGIVGFIGEKDAKEILLKGLEKLEYRGYDSAGIAVQTENGVVVYKEKGRIAKLREIV
DENVATSVGIGHTRWATHGVPSKVNAHPHQSTSKRFTLVHNGVIENYELVKNEYLQDVTFVSETDTEVIVQLIEQQVNTG
LNVEEAFRKVLSLLHGSYAIGLLDAENPNMIYVAKNKSPLLVGVGDNFKVVASDAMAMLQVTDQFIELMDKEVVIVTKES
ITIKNLQGETIERAPFTAELDASDIEKGTYPHFMLKEIDEQPLVIRNIIQKYQDENGEIELDEEIRSAILASDRIYIIAC
GTSYHAGLVGKQFIEKFAKVPVEVHVASEFSYNMPLLTEKPFFIYISQSGETADSRAVLVQTNEMGHKALTITNVPGSTL
SREADYTLPLYAGPEIAVASTKAYTAQLAVLAILAADIAKAKGEVLDFDLTHELGLVANAMEVLCDQKEEMDALAKQFLA
TTRNCFFIGRSVDFYVGLEGALKLKEISYIQAEGFAGGELKHGTIALIEKGTPVIALATQEHVNLGIRGNVKEVVARGAN
PCIISMKGLEMEGDSFVLPAVHEALAPLVAVVPLQLISYYAALHRECDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=33.5766423357664, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI4826742, Length=690, Percent_Identity=33.3333333333333, Blast_Score=328, Evalue=7e-90,
Organism=Escherichia coli, GI1790167, Length=616, Percent_Identity=41.5584415584416, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI87082251, Length=304, Percent_Identity=22.3684210526316, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788651, Length=242, Percent_Identity=26.4462809917355, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532899, Length=721, Percent_Identity=28.9875173370319, Blast_Score=256, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17539970, Length=436, Percent_Identity=35.5504587155963, Blast_Score=228, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17532897, Length=445, Percent_Identity=33.9325842696629, Blast_Score=216, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6322745, Length=428, Percent_Identity=33.6448598130841, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6323731, Length=373, Percent_Identity=29.4906166219839, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=37.5609756097561, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21357745, Length=691, Percent_Identity=32.8509406657019, Blast_Score=341, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 68092; Mature: 68092

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDEVVTCSQGNVSICNGDLNMCGIVGFIGEKDAKEILLKGLEKLEYRGYDSAGIAVQT
CCCCCEEEECCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEE
ENGVVVYKEKGRIAKLREIVDENVATSVGIGHTRWATHGVPSKVNAHPHQSTSKRFTLVH
CCCEEEEECCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
NGVIENYELVKNEYLQDVTFVSETDTEVIVQLIEQQVNTGLNVEEAFRKVLSLLHGSYAI
CCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEE
GLLDAENPNMIYVAKNKSPLLVGVGDNFKVVASDAMAMLQVTDQFIELMDKEVVIVTKES
EEEECCCCCEEEEECCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECC
ITIKNLQGETIERAPFTAELDASDIEKGTYPHFMLKEIDEQPLVIRNIIQKYQDENGEIE
EEEECCCCCCEECCCCEEECCHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCEE
LDEEIRSAILASDRIYIIACGTSYHAGLVGKQFIEKFAKVPVEVHVASEFSYNMPLLTEK
EHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECC
PFFIYISQSGETADSRAVLVQTNEMGHKALTITNVPGSTLSREADYTLPLYAGPEIAVAS
CEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCEEEEE
TKAYTAQLAVLAILAADIAKAKGEVLDFDLTHELGLVANAMEVLCDQKEEMDALAKQFLA
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TTRNCFFIGRSVDFYVGLEGALKLKEISYIQAEGFAGGELKHGTIALIEKGTPVIALATQ
HCCCEEEEECCEEEEEECCCCEEEEHEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEH
EHVNLGIRGNVKEVVARGANPCIISMKGLEMEGDSFVLPAVHEALAPLVAVVPLQLISYY
HHEEECCCCCHHHHHHCCCCCEEEEEECCEECCCCEECHHHHHHHHHHHHHHHHHHHHHH
AALHRECDVDKPRNLAKSVTVE
HHHHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MRLDEVVTCSQGNVSICNGDLNMCGIVGFIGEKDAKEILLKGLEKLEYRGYDSAGIAVQT
CCCCCEEEECCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEE
ENGVVVYKEKGRIAKLREIVDENVATSVGIGHTRWATHGVPSKVNAHPHQSTSKRFTLVH
CCCEEEEECCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
NGVIENYELVKNEYLQDVTFVSETDTEVIVQLIEQQVNTGLNVEEAFRKVLSLLHGSYAI
CCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEE
GLLDAENPNMIYVAKNKSPLLVGVGDNFKVVASDAMAMLQVTDQFIELMDKEVVIVTKES
EEEECCCCCEEEEECCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECC
ITIKNLQGETIERAPFTAELDASDIEKGTYPHFMLKEIDEQPLVIRNIIQKYQDENGEIE
EEEECCCCCCEECCCCEEECCHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCEE
LDEEIRSAILASDRIYIIACGTSYHAGLVGKQFIEKFAKVPVEVHVASEFSYNMPLLTEK
EHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECC
PFFIYISQSGETADSRAVLVQTNEMGHKALTITNVPGSTLSREADYTLPLYAGPEIAVAS
CEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCEEEEE
TKAYTAQLAVLAILAADIAKAKGEVLDFDLTHELGLVANAMEVLCDQKEEMDALAKQFLA
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TTRNCFFIGRSVDFYVGLEGALKLKEISYIQAEGFAGGELKHGTIALIEKGTPVIALATQ
HCCCEEEEECCEEEEEECCCCEEEEHEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEH
EHVNLGIRGNVKEVVARGANPCIISMKGLEMEGDSFVLPAVHEALAPLVAVVPLQLISYY
HHEEECCCCCHHHHHHCCCCCEEEEEECCEECCCCEECHHHHHHHHHHHHHHHHHHHHHH
AALHRECDVDKPRNLAKSVTVE
HHHHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]