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The map label for this gene is rocF [H]

Identifier: 152973999

GI number: 152973999

Start: 159090

End: 159983

Strand: Direct

Name: rocF [H]

Synonym: Bcer98_0147

Alternate gene names: 152973999

Gene position: 159090-159983 (Clockwise)

Preceding gene: 152973998

Following gene: 152974000

Centisome position: 3.89

GC content: 37.58

Gene sequence:

>894_bases
ATGAAGAAAGAAATTTCAATTATTGGAGTTCCAATGGATTTAGGACAACTGCGTCGCGGAGTTGATATGGGGGCAAGTGC
CATTCGTTATGCAGGAGTAATTGAAAGAATTGAGCACATTGGATATGACGTGAAAGATATTGGGGATATACATATTGATA
GAGAGAAAGAGGTAGATGGAAATACAAAATTAAGAAACCTTACACAAGTTGTAAAAGTTTGTAATGAATTAGCAAGTAAA
GTTGATCATATTATAGAAGAAGATCGTTTTCCGCTTGTACTAGGCGGCGATCATAGTATAGCGATTGGGACACTTGCAGG
GGTAGCAAAACATTATAAAAATTTGGGTGTGATTTGGTATGATGCACACGGTGATCTAAATACAGAAGAAACTTCACCGT
CTGGAAATATTCATGGCATGTCGCTTGCTGCAAGTTTAGGATATGGACATCCTTCACTCGTCAATTTATATGAAGCGTAT
CCAAAGGTCAAAAAGGAAAACATCGTAATTATCGGTGCACGCGCATTAGATGAAGGAGAAAAAGAATTTATCCGTAATGA
AGGAATTAAAGTATTTACAATGCATGAAATTGATCGTATGGGTATGACGGCTGTTATGGAAGAAACGATTTCTTATTTAT
CACATACAGATGGTGTTCACTTATCTTTAGATTTAGATGGTTTGGATCCACATGATGCACCGGGGGTTGGCACACCTGTA
ATTGGTGGTCTATCCTATCGTGAAAGTCATTTAGCAATGGAAATGTTAGCTGAAGCTGACATAATTACGTCCGCCGAATT
TGTGGAAGTAAATCCAATTTTAGATGAGAGAAATAAAACTGCAACGACGGCTGTTGCATTAATGGGTTCTTTGTTCGGTG
AAAAACTGAAATAA

Upstream 100 bases:

>100_bases
GTGAATAAGGTGTATATCCATACAAAAAAATGTAGAGTTGAGTCAGACTATATAAAAGATTTAAAATATTTAGCGAAGGC
ATAAAAGGGGGATACTATCG

Downstream 100 bases:

>100_bases
ATGTAAGAAAAGCGGCTGAAATGCTGCTTTTTTTATTTTAAAATAGGAGTATAATAATGAGTTATATTGTACGTTATATT
ATAAAAGTTCGACATCTTAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKKEISIIGVPMDLGQLRRGVDMGASAIRYAGVIERIEHIGYDVKDIGDIHIDREKEVDGNTKLRNLTQVVKVCNELASK
VDHIIEEDRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPSLVNLYEAY
PKVKKENIVIIGARALDEGEKEFIRNEGIKVFTMHEIDRMGMTAVMEETISYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIITSAEFVEVNPILDERNKTATTAVALMGSLFGEKLK

Sequences:

>Translated_297_residues
MKKEISIIGVPMDLGQLRRGVDMGASAIRYAGVIERIEHIGYDVKDIGDIHIDREKEVDGNTKLRNLTQVVKVCNELASK
VDHIIEEDRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPSLVNLYEAY
PKVKKENIVIIGARALDEGEKEFIRNEGIKVFTMHEIDRMGMTAVMEETISYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIITSAEFVEVNPILDERNKTATTAVALMGSLFGEKLK
>Mature_297_residues
MKKEISIIGVPMDLGQLRRGVDMGASAIRYAGVIERIEHIGYDVKDIGDIHIDREKEVDGNTKLRNLTQVVKVCNELASK
VDHIIEEDRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPSLVNLYEAY
PKVKKENIVIIGARALDEGEKEFIRNEGIKVFTMHEIDRMGMTAVMEETISYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIITSAEFVEVNPILDERNKTATTAVALMGSLFGEKLK

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=300, Percent_Identity=40.6666666666667, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI4502215, Length=300, Percent_Identity=38.3333333333333, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI37537722, Length=300, Percent_Identity=26.3333333333333, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1789306, Length=278, Percent_Identity=25.5395683453237, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71996843, Length=236, Percent_Identity=36.864406779661, Blast_Score=151, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6325146, Length=320, Percent_Identity=31.875, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24638886, Length=310, Percent_Identity=31.2903225806452, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32425; Mature: 32425

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEISIIGVPMDLGQLRRGVDMGASAIRYAGVIERIEHIGYDVKDIGDIHIDREKEVDG
CCCCEEEEECCCCHHHHHHCHHCCHHHHHHHHHHHHHHHCCCCHHHCCCEEECCCCCCCC
NTKLRNLTQVVKVCNELASKVDHIIEEDRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHPSLVNLYEAYPKVKKENIVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHEECCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHCCCHH
KEFIRNEGIKVFTMHEIDRMGMTAVMEETISYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIITSAEFVEVNPILDERNKTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKEISIIGVPMDLGQLRRGVDMGASAIRYAGVIERIEHIGYDVKDIGDIHIDREKEVDG
CCCCEEEEECCCCHHHHHHCHHCCHHHHHHHHHHHHHHHCCCCHHHCCCEEECCCCCCCC
NTKLRNLTQVVKVCNELASKVDHIIEEDRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHPSLVNLYEAYPKVKKENIVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHEECCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHCCCHH
KEFIRNEGIKVFTMHEIDRMGMTAVMEETISYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIITSAEFVEVNPILDERNKTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]