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The map label for this gene is folB [H]

Identifier: 152973921

GI number: 152973921

Start: 78657

End: 79019

Strand: Direct

Name: folB [H]

Synonym: Bcer98_0068

Alternate gene names: 152973921

Gene position: 78657-79019 (Clockwise)

Preceding gene: 152973920

Following gene: 152973922

Centisome position: 1.92

GC content: 35.54

Gene sequence:

>363_bases
TTGGATAAAATTTATATTCATGATATGGAATTTTACGGCTATCACGGGGTGTTTCCGGAAGAGAATAAATTAGGACAAAG
ATTTAAGGTAGATTTAACGGTAGAACTAGATTTAAAAAAAGCTGGTGAAAGTGACAACTTAGAGCATTCTGTCAATTATG
GAAAGCTGTTTGAATTGTGTAGACAGATTGTAGAAGAACGAACATATAAACTTGTGGAAAGTATAGCGGAAAATATAGCT
GCAAATATATTGGAACAGTATGGAAGTGTGATGCGTTGCACAGTAAAAGTTATCAAACCTGATCCTCCCATACCAGGACA
TTATCGTTCTGTAGCGGTAGAAATAACGAGAGAACGAACATGA

Upstream 100 bases:

>100_bases
GATTGCTAAAGGTTGTGAAATGATTCGTGTTCATGATGTGAAAGAAATGGCCCGTATGGCAAAGATGATGGATGCAATGA
TTGGCAAGGGGGGAAAGTGA

Downstream 100 bases:

>100_bases
AAAATACAGTTTATATTGCTTTAGGATCGAATATTGGTGATCGCTATACGTACTTAACGCAAGCGGTTGATTTATTGGAT
AAGAATTCTAATGTTCAAGT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKKAGESDNLEHSVNYGKLFELCRQIVEERTYKLVESIAENIA
ANILEQYGSVMRCTVKVIKPDPPIPGHYRSVAVEITRERT

Sequences:

>Translated_120_residues
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKKAGESDNLEHSVNYGKLFELCRQIVEERTYKLVESIAENIA
ANILEQYGSVMRCTVKVIKPDPPIPGHYRSVAVEITRERT
>Mature_120_residues
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKKAGESDNLEHSVNYGKLFELCRQIVEERTYKLVESIAENIA
ANILEQYGSVMRCTVKVIKPDPPIPGHYRSVAVEITRERT

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13906; Mature: 13906

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKKAGESDNLEHSVNYGKLFELC
CCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RQIVEERTYKLVESIAENIAANILEQYGSVMRCTVKVIKPDPPIPGHYRSVAVEITRERT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKKAGESDNLEHSVNYGKLFELC
CCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RQIVEERTYKLVESIAENIAANILEQYGSVMRCTVKVIKPDPPIPGHYRSVAVEITRERT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]