Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 152973919

GI number: 152973919

Start: 76949

End: 77806

Strand: Direct

Name: pabC [H]

Synonym: Bcer98_0066

Alternate gene names: 152973919

Gene position: 76949-77806 (Clockwise)

Preceding gene: 152973918

Following gene: 152973920

Centisome position: 1.88

GC content: 34.27

Gene sequence:

>858_bases
ATGTTAATTTATGTGAATGGTACATATGTAGAAGATACGGAAGCGAAAATCTCTCCGTATGATCACGGGTACCTGTATGG
ACTTGGTGTTTTTGAGACATTTCGCATTTATAATGGGCATCCGTTTCTATTAGATGATCATTATGAACGTTTAATGGATG
CTCTTGCTGCTCTGCAAATCGAATGGGATATGAAGAAAGGAGATATGCTTACTATCCTTAAAGAGTTGCTTTTAAGGAAC
GAATTAAAGCATGCTTATATTCGTTTTAATGTATCAGCTGGTATAGATGAAATAGGATTACAAACAGGCGTATACAAAAA
TCCATCTGTCATTGTATTTATCAAACCTTTAACCCCTCCAGATATAGTAGTAGAAAAGGAAGGGGTTATTTTAAAACAGG
TGCGAAATACACCAGAGGGAAATTTCCGTTTGAAATCGCATCATTATTTAAATAATATTTTAGGAAAACGTGAAATTGGC
AATGCAACGAATAGAGAAGGAATCTTCTTTACGAAGGAAGGTTACGTAGCAGAAGGAATTGTTTCAAATATTTTCTTTGT
AAAAGAAGGAGCTTTATATACGCCTTCTCTTCATACAGGAATTCTAAATGGAATTACTCGTGCATTTATTATAAAAGTTG
CCCAAATGTTAAATATAAAAGTAAAAGAAGGCTTATTTACAAAAGAAGAATTACTTACAGCGGAAGAAGTGTTTGTAACA
AATTCGATTCAAGAAATTGTGCCGCTTCTCCATATAGAAGGAAGAGATTTCCCGGGGAAAGAGGGAGAGATTACAAAAAA
ATTAATTGGTGTATATGAGATGCATAGAGAGAATCTTTGGAGCCGAAATGAATTGTAG

Upstream 100 bases:

>100_bases
CGATTGAAGGCGTGCAGTTTCATCCGGAATCGATAATGACTTCTCATGGAAAAGAGCTATTGGAAAACTTTATTCAGAAA
TATAGCTCGAGTGCAGTGTC

Downstream 100 bases:

>100_bases
AGGGGAGATATAGAACTTGAAATGGAACTATGATTTGCGCTGTGGTGAATATACATTAAATTTAAATGAAAAAACATTAG
TCATGGGGATTTTGAATGTA

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLIYVNGTYVEDTEAKISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYERLMDALAALQIEWDMKKGDMLTILKELLLRN
ELKHAYIRFNVSAGIDEIGLQTGVYKNPSVIVFIKPLTPPDIVVEKEGVILKQVRNTPEGNFRLKSHHYLNNILGKREIG
NATNREGIFFTKEGYVAEGIVSNIFFVKEGALYTPSLHTGILNGITRAFIIKVAQMLNIKVKEGLFTKEELLTAEEVFVT
NSIQEIVPLLHIEGRDFPGKEGEITKKLIGVYEMHRENLWSRNEL

Sequences:

>Translated_285_residues
MLIYVNGTYVEDTEAKISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYERLMDALAALQIEWDMKKGDMLTILKELLLRN
ELKHAYIRFNVSAGIDEIGLQTGVYKNPSVIVFIKPLTPPDIVVEKEGVILKQVRNTPEGNFRLKSHHYLNNILGKREIG
NATNREGIFFTKEGYVAEGIVSNIFFVKEGALYTPSLHTGILNGITRAFIIKVAQMLNIKVKEGLFTKEELLTAEEVFVT
NSIQEIVPLLHIEGRDFPGKEGEITKKLIGVYEMHRENLWSRNEL
>Mature_285_residues
MLIYVNGTYVEDTEAKISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYERLMDALAALQIEWDMKKGDMLTILKELLLRN
ELKHAYIRFNVSAGIDEIGLQTGVYKNPSVIVFIKPLTPPDIVVEKEGVILKQVRNTPEGNFRLKSHHYLNNILGKREIG
NATNREGIFFTKEGYVAEGIVSNIFFVKEGALYTPSLHTGILNGITRAFIIKVAQMLNIKVKEGLFTKEELLTAEEVFVT
NSIQEIVPLLHIEGRDFPGKEGEITKKLIGVYEMHRENLWSRNEL

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=293, Percent_Identity=28.3276450511945, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787338, Length=237, Percent_Identity=25.7383966244726, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 32545; Mature: 32545

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00014 ER_TARGET ; PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYVNGTYVEDTEAKISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYERLMDALAALQI
CEEEEECEEEECCCCCCCCCCCCEEEEEHHHEEEEEECCCCEEECHHHHHHHHHHHHEEE
EWDMKKGDMLTILKELLLRNELKHAYIRFNVSAGIDEIGLQTGVYKNPSVIVFIKPLTPP
EECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHCCCCCCCCCEEEEEECCCCC
DIVVEKEGVILKQVRNTPEGNFRLKSHHYLNNILGKREIGNATNREGIFFTKEGYVAEGI
CEEEECCCCHHHHHHCCCCCCEEECHHHHHHHHHCCHHCCCCCCCCCEEEECCCCCHHHH
VSNIFFVKEGALYTPSLHTGILNGITRAFIIKVAQMLNIKVKEGLFTKEELLTAEEVFVT
HHHEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHH
NSIQEIVPLLHIEGRDFPGKEGEITKKLIGVYEMHRENLWSRNEL
CCHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLIYVNGTYVEDTEAKISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYERLMDALAALQI
CEEEEECEEEECCCCCCCCCCCCEEEEEHHHEEEEEECCCCEEECHHHHHHHHHHHHEEE
EWDMKKGDMLTILKELLLRNELKHAYIRFNVSAGIDEIGLQTGVYKNPSVIVFIKPLTPP
EECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHCCCCCCCCCEEEEEECCCCC
DIVVEKEGVILKQVRNTPEGNFRLKSHHYLNNILGKREIGNATNREGIFFTKEGYVAEGI
CEEEECCCCHHHHHHCCCCCCEEECHHHHHHHHHCCHHCCCCCCCCCEEEECCCCCHHHH
VSNIFFVKEGALYTPSLHTGILNGITRAFIIKVAQMLNIKVKEGLFTKEELLTAEEVFVT
HHHEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHH
NSIQEIVPLLHIEGRDFPGKEGEITKKLIGVYEMHRENLWSRNEL
CCHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]